Valproate prevents dysregulation of spinal glutamate and reduces the development of hypersensitivity in rats after peripheral nerve injury.
Yoshizumi M, Eisenach JC, Hayashida K. Valproate prevents dysregulation of spinal glutamate and reduces the development of hypersensitivity in rats after peripheral nerve injury. J Pain. 2013 Nov; 14(11):1485-91.