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TanYa M. Gwathmey-Williams PhD

TitleAssociate Professor
InstitutionWake Forest School of Medicine
DepartmentSurgery, Hypertension
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Files DC, Gibbs KW, Schaich CL, Collins SP, Gwathmey TM, Casey JD, Self WH, Chappell MC. A Pilot Study to Assess the Circulating Renin-Angiotensin-System in COVID-19 Acute Respiratory Failure. Am J Physiol Lung Cell Mol Physiol. 2021 05 19. PMID: 34009036.
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    2. Chappell MC, Pirro NT, South AM, Gwathmey TM. Concerns on the Specificity of Commercial ELISAs for the Measurement of Angiotensin (1-7) and Angiotensin II in Human Plasma. Hypertension. 2021 03 03; 77(3):e29-e31. PMID: 33399002.
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    3. Fatima Ryalat, N Cruz-Diaz, W Graham, T Gwathmey-Williams, PE Gallagher, E A Tallant, LM Yamaleyeva, DI Diz. Sex And Age Specific Circulating Aldosterone Changes In Transgenic Hypertensive (mRen2)27 Rats And Hannover Sprague Dawley (SD) Rats And Its Association With Blood Pressure And Cardiac Function. Hypertension. 2020; 76(Suppl_1):AP045. View Publication.
    4. South AM, Shaltout HA, Gwathmey TM, Jensen ET, Nixon PA, Diz DI, Chappell MC, Washburn LK. Lower urinary a-Klotho is associated with lower angiotensin-(1-7) and higher blood pressure in young adults born preterm with very low birthweight. J Clin Hypertens (Greenwich). 2020 06; 22(6):1033-1040. PMID: 32475043.
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    5. Gwathmey TM and Ard J. Nutritional Influences on Blood Pressure. Nutrition Guide for Physicians and Related Healthcare Professionals 3rd Edition. Springer, New York. Editors: Wilson, Temple and Bray . 2020.
    6. TanYa M. Gwathmey, Allyn C. Howlett . Instruction Across an Educational Spectrum as a Tool for Building Teaching Skills in the Biomedical Sciences. FASEB J. 2018; 32(1):lb228. View Publication.
    7. TanYa M Gwathmey, Lillian Zerihun, Stephen W Simington, Mark C Chappell, Lisa K Washburn . Antenatal Betamethasone Exposure Increases Oxidative Stress in African-American Adolescents Born Prematurely. Circulation. 2018; 127(suppl_12):AP241. View Publication.
    8. Sierra A. Nance, A’ja V. Duncan, Kristen G. Hairston, TanYa M. Gwathmey . Cardiometabolic Status in Obese African American Women is Linked to Glycative Stress. FASEB J. 2017; 31(1):31.5. View Publication.
    9. Sierra A. Nance, A’ja V. Duncan, TanYa M. Gwathmey, Kristen G. Hairston . Soluble Dietary Fiber in Obesity-Associated Inflammation and Oxidative Stress in African American Women. FASEB J. 2017; 31(1):434.2. View Publication.
    10. Lillian M. Zerihun, Patricia A. Nixon, Lisa K. Washburn, TanYa M. Gwathmey . Racial Differences in Serum Cystatin-C Following Antenatal Corticosteroid Exposure. FASEB J. 2017; 31(1):lb825. View Publication.
    11. Wilson BA, Cruz-Diaz N, Su Y, Rose JC, Gwathmey TM, Chappell MC. Angiotensinogen import in isolated proximal tubules: evidence for mitochondrial trafficking and uptake. Am J Physiol Renal Physiol. 2017 05 01; 312(5):F879-F886. PMID: 27903492.
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    12. Rodriguez CJ, Gwathmey TM, Jin Z, Schwartz J, Beech BM, Sacco RL, Di Tullio MR, Homma S. Perceived Discrimination and Nocturnal Blood Pressure Dipping Among Hispanics: The Influence of Social Support and Race. Psychosom Med. 2016 09; 78(7):841-50. PMID: 27136505.
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    13. Gwathmey TM, Tallant EA, Howlett AC, Diz DI. Programs to Recruit and Retain a More Diverse Workforce in Biomedical Sciences Research. J Best Pract Health Prof Divers. 2016; 9(1):1188-1194. PMID: 28868526.
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    14. Wilson BA, Nautiyal M, Gwathmey TM, Rose JC, Chappell MC. Evidence for a mitochondrial angiotensin-(1-7) system in the kidney. Am J Physiol Renal Physiol. 2016 04 01; 310(7):F637-F645. PMID: 26697984.
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    15. Bryan A Wilson, Nancy T Pirro, TanYa M Gwathmey, James C Rose, Mark C Chappell . A Mitochondrial Renin-Angiotensin System: Internalization of Angiotensinogen. Hypertension. 2015; 66(suppl_1):A020. View Publication.
    16. Tannan SC, Pappou IP, Gwathmey FW, Freilich AM, Chhabra AB. The Extended Flexor Carpi Radialis Approach for Concurrent Carpal Tunnel Release and Volar Plate Osteosynthesis for Distal Radius Fracture. J Hand Surg Am. 2015 Oct; 40(10):2026-2031.e1. PMID: 26304737.
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    17. Gwathmey TM, Willis MS, Tatreau J, Wang S, McCudden CR. Clinical Relevance of Trace Bands on Serum Electrophoresis in Patients Without a History of Gammopathy. EJIFCC. 2015 Mar; 26(2):114-24. PMID: 27683487.
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    18. Wilson BA, Cruz-Diaz N, Marshall AC, Pirro NT, Su Y, Gwathmey TM, Rose JC, Chappell MC. An angiotensin-(1-7) peptidase in the kidney cortex, proximal tubules, and human HK-2 epithelial cells that is distinct from insulin-degrading enzyme. Am J Physiol Renal Physiol. 2015 Mar 15; 308(6):F594-601. PMID: 25568136.
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    19. Washburn LK, Brosnihan KB, Chappell MC, Diz DI, Gwathmey TM, Nixon PA, Russell GB, Snively BM, O'Shea TM. The renin-angiotensin-aldosterone system in adolescent offspring born prematurely to mothers with preeclampsia. J Renin Angiotensin Aldosterone Syst. 2015 Sep; 16(3):529-38. PMID: 24737639.
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    20. TanYa Gwathmey, Mark Chappell, Patricia Nixon, Lisa Washburn . Prenatal steroid exposure promotes expression of renal injury indices in African American females. FASEB J. 2014; 28(1):1134.11. View Publication.
    21. TanYa M Gwathmey, Patricia Nixon, Mark Chappell, Lisa Washburn . 25-Hydroxyvitamin D and Body Mass Index in Female Adolescents. FASEB J. 2012; 26(1):1093.15. View Publication.
    22. Gwathmey TM, Alzayadneh EM, Pendergrass KD, Chappell MC. Novel roles of nuclear angiotensin receptors and signaling mechanisms. . 2012 Mar 01; 302(5):R518-30. PMID: 22170620.
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    23. TanYa M Gwathmey, Patricia A Nixon, T. Michael O’Shea, K. Bridget Brosnihan, Mark C Chappell, Lisa K Washburn. Premature Birth is Associated With Higher Diastolic Blood Pressure and Reduced Vitamin D in African American Adolescents. Hypertension. 2011; 58(5):e165; P498. View Publication.
    24. Gwathmey TM, Shaltout HA, Rose JC, Diz DI, Chappell MC. Glucocorticoid-induced fetal programming alters the functional complement of angiotensin receptor subtypes within the kidney. Hypertension. 2011 Mar; 57(3):620-6. PMID: 21220702.
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    25. Gwathmey TM, Westwood BM, Pirro NT, Tang L, Rose JC, Diz DI, Chappell MC. Nuclear angiotensin-(1-7) receptor is functionally coupled to the formation of nitric oxide. Am J Physiol Renal Physiol. 2010 Nov; 299(5):F983-90. PMID: 20810609.
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    26. TanYa M. Gwathmey, Hossam A. Shaltout, Patricia A. Nixon, James C. Rose, Lisa K. Washburn, Mark C. Chappell . Sex and Racial Background Influence Angiotensin Peptide Metabolism in Young Adults. FASEB J. 2010; 24(1):1024.31. View Publication.
    27. TanYa M. Gwathmey, Hossam A. Shaltout, Patricia A. Nixon, James C. Rose, Lisa K. Washburn, Mark C. Chappell . Antenatal Steroid Exposure is Associated with Reduced Urinary ACE2 Activity in Adolescents. FASEB J. 2010; 24(1):605.1. View Publication.
    28. Bryan Anthony Wilson , TanYa Gwathmey, Nancy Pirro, Mark C Chappell . Evidence for Protein Kinase C Dependent Stimulation of Reactive Oxygen Species in Isolated Nuclei of Renal Epithelial Cells. FASEB J. 2010; 24(1):1059.3. View Publication.
    29. Brian Westwood, TanYa Gwathmey, Hossam Shaltout, Debra Diz, James Rose, Mark Chappell . Immunocytochemical Distribution of the Ang-(1–7)/Mas Receptor in the Sheep Kidney. FASEB J. 2010; 24(1):605.6. View Publication.
    30. Gwathmey TM, Pendergrass KD, Reid SD, Rose JC, Diz DI, Chappell MC. Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus. Hypertension. 2010 Jan; 55(1):166-71. PMID: 19948986.
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    31. Pendergrass KD, Gwathmey TM, Michalek RD, Grayson JM, Chappell MC. The angiotensin II-AT1 receptor stimulates reactive oxygen species within the cell nucleus. Biochem Biophys Res Commun. 2009 Jun 26; 384(2):149-54. PMID: 19409874.
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    32. TanYa M. Gwathmey, Karl D. Pendergrass, Nancy T. Pirro, Hossam A. Shaltout, Sean D. Reid, James C. Rose, Mark C. Chappell . Nuclear AT2 receptors mediate angiotensin II-dependent generation of nitric oxide. FASEB J. 2009; 23(1):606.9. View Publication.
    33. Karl D Pendergrass, TanYa M Gwathmey, Jason M Grayson, Mark C Chappell . Protein Kinase C and PI3 Kinase Mediate Ang II-Dependent Generation of Reactive Oxygen Species in Renal Nuclei. FASEB J. 2009; 23(1):803.7. View Publication.
    34. Gwathmey TM, Shaltout HA, Pendergrass KD, Pirro NT, Figueroa JP, Rose JC, Diz DI, Chappell MC. Nuclear angiotensin II type 2 (AT2) receptors are functionally linked to nitric oxide production. Am J Physiol Renal Physiol. 2009 Jun; 296(6):F1484-93. PMID: 19244399.
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    35. Karl D Pendergrass, TanYa M Gwathmey, Ryan D Michalek, Jason M Grayson, Mark C Chappell. Nuclear Angiotensin II AT1 Receptors Mediate the Formation of Reactive Oxygen Species. Hypertension. 2008; 52(4):e48;066. View Publication.
    36. TanYa M Gwathmey, Karl D Pendergrass, Sean D Reid, James C Rose, Mark C Chappell. Evidence that the ACE2-Angiotensin-(1–7) Pathway Counterbalances Angiotensin II-Induced Formation of Reactive Oxygen Species in Renal Nuclei. Hypertension. 2008; 52(4):e124-e125; LB030. View Publication.
    37. TanYa M. Gwathmey, Hossam A Shaltout, Patricia A Nixon, T. Michael O’Shea, James C Rose, Lisa K Washburn, Mark C Chappell . Gender differences in urinary ACE and ACE2 activities in adolescents. FASEB J. 2008; 22(1):940.6. View Publication.
    38. TanYa M. Gwathmey, Hossam A Shaltout, Debra I Diz, Jorge P Figueroa, James C Rose, Mark C Chappell . Steroid - induced fetal programming alters angiotensin II receptor subtype expression in the sheep kidney. FASEB J. 2008; 22(1):735.15. View Publication.
    39. TanYa M Gwathmey, Debra I Diz, Nancy T Pirro, Jorge Figueroa, James C Rose, Mark C Chappell. Nuclear Angiotensin II-Type 2 Receptors Are Differentially Expressed in the Sheep Kidney. Hypertension. 2007; 50(4):e97;P6. View Publication.
    40. Gwathmey TM, Ignotz GG, Mueller JL, Manjunath P, Suarez SS. Bovine seminal plasma proteins PDC-109, BSP-A3, and BSP-30-kDa share functional roles in storing sperm in the oviduct. Biol Reprod. 2006 Oct; 75(4):501-7. PMID: 16790686.
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    41. Gwathmey TM, Ignotz GG, Suarez SS. PDC-109 (BSP-A1/A2) promotes bull sperm binding to oviductal epithelium in vitro and may be involved in forming the oviductal sperm reservoir. Biol Reprod. 2003 Sep; 69(3):809-15. PMID: 12748117.
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    42. Ignotz GG, Lo MC, Perez CL, Gwathmey TM, Suarez SS. Characterization of a fucose-binding protein from bull sperm and seminal plasma that may be responsible for formation of the oviductal sperm reservoir. Biol Reprod. 2001 Jun; 64(6):1806-11. PMID: 11369612.
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    43. Gwathmey T, Blackmore PF, Mahony MC. Progesterone-induced calcium influx in cynomolgus monkey (Macaca fascicularis) spermatozoa. J Androl. 2000 Jul-Aug; 21(4):534-40. PMID: 10901439.
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    44. Mahony MC, Gwathmey T. Protein tyrosine phosphorylation during hyperactivated motility of cynomolgus monkey (Macaca fascicularis) spermatozoa. Biol Reprod. 1999 May; 60(5):1239-43. PMID: 10208990.
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