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Hossam A. Shaltout PhD

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentObstetrics and Gynecology
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    Other Positions
    TitleProfessor
    InstitutionWake Forest School of Medicine
    DepartmentSurgery, Hypertension


    Collapse Research 
    Collapse research activities and funding
    P01HL051952     (FERRARIO, CARLOS M)Apr 1, 1994 - Mar 31, 2021
    NIH
    Vaso-Hormonal Mechanisms in Hypertension
    Role: Co-Investigator
    P01HD047584     (ROSE, JAMES C.)Jul 1, 2004 - Jul 31, 2017
    NIH
    Prenatal Events-Postnatal Consequences
    Role: Co-Investigator
    U01DK073974     (KOCH, KENNETH L)Apr 15, 2006 - Aug 31, 2021
    NIH
    Subtypes of Gastroparesis
    Role: Co-Investigator
    R01HL087103     (SHIVELY, CAROL A.)Dec 1, 2006 - Mar 31, 2020
    NIH
    Dietary Mitigation of Psychosocial Stress Effects on CVD Risk
    Role: Co-Investigator
         (Fortunato, John)Jan 1, 2011 - Dec 31, 2013
    AHA
    Elevated Supine MAP in Children with Cardiovascular Dysautonomia
    Role: Co-Investigator
         (Brinkley, Tin)Jan 1, 2013 - Dec 31, 2014
    AHA
    Exercise, Weight loss, and Arterial Stiffness in Obese, Older Adults
    Role: Co-Investigator
         (Tegeler, Charles)Jul 1, 2014 - Oct 31, 2015
    DOD
    HIRREM for Mitigation of PTSD Symptoms in Military Personnel
    Role: Co-Investigator
         (Shaltout, Hossam)Jan 1, 2016 - Dec 31, 2021
    AHA
    Comprehensive assessment of vascular and autonomic function in children with low vitamin D
    Role: Principal Investigator
    R01AG057013     (DELBONO, OSVALDO)Sep 1, 2017 - May 31, 2022
    NIH
    The Role of the Sympathetic Nervous System in the Onset and Development of Sarcopenia
    Role: Co-Investigator
    R01HL146818     (CHAPPELL, MARK C)Aug 15, 2019 - Jul 31, 2024
    NIH
    Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm
    Role: Principal Investigator
    R01DK124639     (SHIVELY, CAROL A.)Apr 1, 2020 - Mar 31, 2024
    NIH
    Psychosocial Stress Effects on Regenerative Medicine Therapies for Lower Urinary Tract Disorders in Nonhuman Primates
    Role: Co-Investigator
    R01AG066910     (BRINKLEY, TINA E)Apr 15, 2020 - Dec 31, 2024
    NIH
    The POINTER Neurovascular Ancillary Study
    Role: Principal Investigator
    K23HL148394     (SOUTH, ANDREW MICHAEL)Aug 3, 2020 - Jun 30, 2025
    NIH
    The role of angiotensin-(1-7) in hypertension and hypertension-induced heart and kidney damage
    Role: Mentor
    R01HL158622     (JURASCHEK, STEPHEN P)Jul 20, 2021 - May 31, 2026
    NIH
    Prognostic Implications of Home-Based Blood Pressure Monitoring in Older Adults
    Role: Co-Investigator
    K01AG073581     (SCHAICH, CHRISTOPHER)Aug 15, 2021 - Apr 30, 2025
    NIH
    Cardiac Autonomic Function, Cognitive Performance, and Neurocognitive Outcomes
    Role: Mentor
    R01AG071545     (DELBONO, OSVALDO)Feb 15, 2022 - Jan 31, 2027
    NIH
    Role of Central Autonomic Relays in Aging Sarcopenia
    Role: Co-Investigator
    1P01CA269048-01A1     (Donny, Eric and Sutfin, Erin)May 3, 2023 - Apr 30, 2028
    NIH
    MARVEL: A Multidisciplinary Assessment of Risks from Vaping during Early Life
    Role Description: OVERALL Adolescence is a critical time of development where teens increase their identification with peers, establish their independence and autonomy, and some begin experimenting with substances, including vaping products. Project MARVEL takes a multidisciplinary approach to assess the impact of youth vaping on health with projects that address vaping behavior, dependence, well-being, brain structure and function, respiratory health, and how to inform adolescents about the health harms to stem the epidemic of youth vaping.
    Role: Co-Lead Project 2

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Brouwer ECJ, Floyd WN, Jensen ET, O'Connell N, Shaltout HA, Washburn LK, South AM. Risk of Obesity and Unhealthy Central Adiposity in Adolescents Born Preterm With Very Low Birthweight Compared to Term-Born Peers. Child Obes. 2024 Feb 22. PMID: 38387005.
      Citations:    
    2. Schiff AF, Deines D, Jensen ET, O'Connell N, Perry CJ, Shaltout HA, Washburn LK, South AM. Duration of Simultaneous Exposure to High-Risk and Lower-Risk Nephrotoxic Antimicrobials in the Neonatal Intensive Care Unit (NICU) and Future Adolescent Kidney Health. J Pediatr. 2024 Jan; 264:113730. PMID: 37722552.
      Citations:    
    3. Tegeler CL, Munger Clary H, Shaltout HA, Simpson SL, Gerdes L, Tegeler CH. Cereset Research Standard Operating Procedures for Insomnia: A Randomized, Controlled Clinical Trial. Glob Adv Integr Med Health. 2023; 12:27536130221147475. PMID: 36816469.
      Citations:    
    4. Riojas AM, Reeves KD, Shade RE, Puppala SR, Christensen CL, Birnbaum S, Glenn JP, Li C, Shaltout H, Hall-Ursone S, Cox LA. Blood pressure and the kidney cortex transcriptome response to high-sodium diet challenge in female nonhuman primates. Physiol Genomics. 2022 Nov 01; 54(11):443-454. PMID: 36062883.
      Citations:    
    5. Angelica M. Riojas, Kimberly D. Spradling-Reeves, Robert E. Shade, Sobha R. Puppala, Clinton L. Christensen, Shifra Birnbaum, Jeremy P. Glenn, Cun Li, Hossam Shaltout, Shannan Hall-Ursone and Laura A. Cox. Blood pressure and the kidney cortex transcriptome response to high sodium diet challenge in female nonhuman primates. Journal of Clinical and Translational Science. 2022; 6(s1):58-59. View Publication.
    6. Koch KL, Van Natta M, Parkman HP, Grover M, Abell TL, McCallum RW, Shaltout HA, Sarosiek I, Farrugia G, Shulman RJ, Tonascia J, Miriel L, Hamilton F, Pasricha PJ. Effect of liquid and solid test meals on symptoms and gastric myoelectrical activity in patients with gastroparesis and functional dyspepsia. Neurogastroenterol Motil. 2023 Feb; 35(2):e14376. PMID: 35411675.
      Citations:    
    7. Silverstein-Metzler MG, Frye BM, Justice JN, Clarkson TB, Appt SE, Jeffrey Carr J, Register TC, Albu-Shamah M, Shaltout HA, Shively CA. Psychosocial stress increases risk for type 2 diabetes in female cynomolgus macaques consuming a western diet. Psychoneuroendocrinology. 2022 May; 139:105706. PMID: 35259592.
      Citations:    
    8. Fortunato JE, Laurienti PJ, Wagoner AL, Shaltout HA, Diz DI, Silfer JL, Burdette JH. Children with chronic nausea and orthostatic intolerance have unique brain network organization: A case-control trial. Neurogastroenterol Motil. 2021 Oct 04; e14271. PMID: 34606665.
      Citations:    
    9. Ryalat, F; Shaltout, HA; Diz, DI; Wolfe, SQ. HYPERTENSION. Sex Differences In Augmentation Index And Aortic Pulse Pressure Among Patients Diagnosed With Acute Primary Intracerebral Hemorrhage. 2021; 78 Suppl_1:AP150. View Publication.
    10. Hossam A Shaltout. Supplementation Improves Measures Of Arterial Stiffness And Vascular Function In Adolescents Suffering From Orthostatic Intolerance. Hypertension. 2021; 78(Suppl_1):AP223. View Publication.
    11. Hossam A Shaltout, Catherine Tegeler, Lindsay Howard, Kenzie Brown, Faiza Asif-Fraz, Dawn Kellar and Charles H Tegeler. Use Of A Noninvasive, Closed-loop, Allostatic, Neurotechnology Reduced Blood Pressure And Improved Sleep In Heterogeneous Cohort. Hypertension. 2021; 78(Suppl_1):AP205. View Publication.
    12. Catherine Tegeler, Lindsay Howard, Kenzie L Brown, Faiza Asif-Fraz, Dawn C Kellar, Hossam A Shaltout and Charles H Tegeler. Improvement Of Autonomic Function, Sleep, Depression, Anxiety, And Stress In Military Personnel With Traumatic Stress After Use Of A Closed Loop Neurotechnology. Hypertension. 2021; 78(Suppl_1):AP206. View Publication.
    13. Karere GM, Cox LA, Bishop AC, South AM, Shaltout HA, Mercado-Deane MG, Cuda S. Sex Differences in MicroRNA Expression and Cardiometabolic Risk Factors in Hispanic Adolescents with Obesity. J Pediatr. 2021 Apr 06. PMID: 33831442.
      Citations:    
    14. Cohen JB, South AM, Shaltout HA, Sinclair MR, Sparks MA. Renin-angiotensin system blockade in the COVID-19 pandemic. Clin Kidney J. 2021 Mar; 14(Suppl 1):i48-i59. PMID: 33796285.
      Citations:    
    15. Shively CA, Appt SE, Chen H, Day SM, Frye BM, Shaltout HA, Silverstein-Metzler MG, Snyder-Mackler N, Uberseder B, Vitolins MZ, Register TC. Mediterranean diet, stress resilience, and aging in nonhuman primates. Neurobiol Stress. 2020 Nov; 13:100254. PMID: 33344709.
      Citations:    
    16. Tegeler CL, Shaltout HA, Lee SW, Simpson SL, Gerdes L, Tegeler CH. High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM) improves symptoms and autonomic function for insomnia: A randomized, placebo-controlled clinical trial. Brain Behav. 2020 11; 10(11):e01826. PMID: 32940419.
      Citations:    
    17. Hossam A Shaltout. Vitamin D Supplementation Improves Autonomic Response To Head Up Tilt In Adolescents Suffering From Orthostatic Intolerance. Hypertension. 2020; 76(Suppl_1):AP198. View Publication.
    18. South AM, Shaltout HA, Gwathmey TM, Jensen ET, Nixon PA, Diz DI, Chappell MC, Washburn LK. Lower urinary a-Klotho is associated with lower angiotensin-(1-7) and higher blood pressure in young adults born preterm with very low birthweight. J Clin Hypertens (Greenwich). 2020 06; 22(6):1033-1040. PMID: 32475043.
      Citations:    
    19. CH Tegeler, CL Tegeler, LJ Howard, KL Brown, DC Kellar, L Gerdes, HA Shaltout. A Pilot, Placebo-controlled Trial of Closed-Loop, Artificial Intelligence Driven, Acoustic Neuromodulation for Insomnia. Sleep. 2020; 43(Suppl_1):A200; 0523. View Publication.
    20. CL Tegeler, LJ Howard, KL Brown, DC Kellar, HA Shaltout, L Gerdes, CH Tegeler. Exploratory Use of Artificial Intelligence Driven Acoustic Neuromodulation Improved Sleep, Depression, Anxiety, and Stress in Adults with Persisting Post-Concussion Symptoms. Sleep. 2020; 43(Suppl_1): A207–A208; 0542. View Publication.
    21. CL Tegeler, LJ Howard, KL Brown, DC Kellar, HA Shaltout, L Gerdes, CH Tegeler. Exploratory Study of Closed-Loop, Artificial Intelligence Driven Neurotechnology Improves Self-Reported Symptoms of Insomnia, Stress, and Anxiety in First Responders. Sleep. 2020; 43(Suppl_1):A207; 0541. View Publication.
    22. Tegeler CL, Shaltout HA, Lee SW, Simpson SL, Gerdes L, Tegeler CH. Pilot Trial of a Noninvasive Closed-Loop Neurotechnology for Stress-Related Symptoms in Law Enforcement: Improvements in Self-Reported Symptoms and Autonomic Function. Glob Adv Health Med. 2020; 9:2164956120923288. PMID: 32426179.
      Citations:    
    23. South AM, Shaltout HA, Nixon PA, Diz DI, Jensen ET, O'Shea TM, Chappell MC, Washburn LK. Association of circulating uric acid and angiotensin-(1-7) in relation to higher blood pressure in adolescents and the influence of preterm birth. J Hum Hypertens. 2020 12; 34(12):818-825. PMID: 32346123.
      Citations:    
    24. Schaich CL, Malaver D, Chen H, Shaltout HA, Zeki Al Hazzouri A, Herrington DM, Hughes TM. Association of Heart Rate Variability With Cognitive Performance: The Multi-Ethnic Study of Atherosclerosis. J Am Heart Assoc. 2020 04 07; 9(7):e013827. PMID: 32200711.
      Citations:    
    25. Brown CL, Myers K, South AM, Shaltout HA, Jensen ET, Nixon PA, Washburn LK. Influence of race on the effect of premature birth on salivary cortisol response to stress in adolescents. Pediatr Res. 2020 05; 87(6):1100-1105. PMID: 31783400.
      Citations:    
    26. Nixon PA, Shaltout HA, South AM, Jensen ET, O'Shea TM, Brown CL, Washburn LK. Antenatal Steroid Exposure, Aerobic Fitness, and Physical Activity in Adolescents Born Preterm with Very Low Birth Weight. J Pediatr. 2019 12; 215:98-106.e2. PMID: 31604627.
      Citations:    
    27. Hossam A Shaltout. Vitamin D Supplementation Improves Vascular Function in Adolescents Suffering from Orthostatic Intolerance. Hypertension. 2019; 74(Suppl_1):AP2062. View Publication.
    28. Adler-Neal AL, Waugh CE, Garland EL, Shaltout HA, Diz DI, Zeidan F. The Role of Heart Rate Variability in Mindfulness-Based Pain Relief. J Pain. 2020 Mar - Apr; 21(3-4):306-323. PMID: 31377215.
      Citations:    
    29. Wagoner AL, Olson JD, Westwood BM, Fortunato JE, Diz DI, Shaltout HA. Children with orthostatic intolerance exhibit elevated markers of inflammation in the dorsal medulla. . 2019 08 01; 317(2):H323-H329. PMID: 31225987.
      Citations:    
    30. Yamaleyeva LM, Brosnihan KB, Elsangeedy E, McGee C, Shi S, Caudell D, Miller C, Varagic J, Bader M, Dechend R, Shaltout HA. Systemic Outcomes of (Pyr1)-Apelin-13 Infusion at Mid-Late Pregnancy in a Rat Model with Preeclamptic Features. Sci Rep. 2019 06 12; 9(1):8579. PMID: 31189936.
      Citations:    
    31. Hendricks AS, Lawson MJ, Figueroa JP, Chappell MC, Diz DI, Shaltout HA. Central ANG-(1-7) infusion improves blood pressure regulation in antenatal betamethasone-exposed sheep and reveals sex-dependent effects on oxidative stress. . 2019 06 01; 316(6):H1458-H1467. PMID: 30951367.
      Citations:    
    32. Nautiyal M, Shaltout HA, Chappell MC, Diz DI. Comparison of Candesartan and Angiotensin-(1-7) Combination to Mito-TEMPO Treatment for Normalizing Blood Pressure and Sympathovagal Balance in (mREN2)27 Rats. J Cardiovasc Pharmacol. 2019 03; 73(3):143-148. PMID: 30540685.
      Citations:    
    33. AlFadly ED, Elzahhar PA, Tramarin A, Elkazaz S, Shaltout H, Abu-Serie MM, Janockova J, Soukup O, Ghareeb DA, El-Yazbi AF, Rafeh RW, Bakkar NZ, Kobeissy F, Iriepa I, Moraleda I, Saudi MNS, Bartolini M, Belal ASF. Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase. Eur J Med Chem. 2019 Apr 01; 167:161-186. PMID: 30771604.
      Citations:    
    34. South AM, Shaltout HA, Washburn LK, Hendricks AS, Diz DI, Chappell MC. Fetal programming and the angiotensin-(1-7) axis: a review of the experimental and clinical data. Clin Sci (Lond). 2019 01 15; 133(1):55-74. PMID: 30622158.
      Citations:    
    35. Chris Schaich, Diego Malaver, Hossam A Shaltout, Adina Zeki Al Hazzouri, David M Herrington, Timothy M Hughes. Heart Rate Variability is Associated with Future Global Cognitive Performance: the Multi-Ethnic Study of Atherosclerosis. Hypertension. 2018; 72(Suppl_1):AP301. View Publication.
    36. Hossam A Shaltout, Patricia A Nixon, Mark C Chappell, Debra I Diz, Andrew M South, Elizabeth T Jensen, Lisa K Washburn. Impaired Autonomic Function in Young Adults Born Preterm With Very Low Birth Weight is Associated With Elevated Serum Uric Acid Levels. Hypertension. 2018; 72(Suppl_1):Abstract 135. View Publication.
    37. Hossam A Shaltout. Vitamin D Supplementation Improves Cardiovascular Response to Head Up Tilt in Adolescents Suffering from Syncope. Hypertension. 2018; 72(Suppl_1):AP396. View Publication.
    38. Andrew M South, Patricia A Nixon, Mark C Chappell, Debra I Diz, Elizabeth T Jensen, Hossam A Shaltout, Lisa K Washburn. Preterm Birth is Associated with Increased Blood Pressure and Increased Urinary Angiotensinogen in Young Adults. Hypertension. 2018; 72(Suppl_1):AP306. View Publication.
    39. South AM, Nixon PA, Chappell MC, Diz DI, Russell GB, Shaltout HA, O'Shea TM, Washburn LK. Obesity is Associated with Higher Blood Pressure and Higher Levels of Angiotensin II but Lower Angiotensin-(1-7) in Adolescents Born Preterm. J Pediatr. 2019 02; 205:55-60.e1. PMID: 30404738.
      Citations:    
    40. South AM, Nixon PA, Chappell MC, Diz DI, Russell GB, Jensen ET, Shaltout HA, O'Shea TM, Washburn LK. Association between preterm birth and the renin-angiotensin system in adolescence: influence of sex and obesity. J Hypertens. 2018 10; 36(10):2092-2101. PMID: 29846325.
      Citations:    
    41. Hendricks AS, Shaltout HA, Westwood BM, Chappell MC, Diz DI. Sex-dependent expression of brain medullary MAP and PI3 kinases in adult sheep with antenatal betamethasone exposure. Clin Sci (Lond). 2018 09 14; 132(17):1953-1962. PMID: 30026259.
      Citations:    
    42. South AM, Nixon PA, Chappell MC, Diz DI, Russell GB, Jensen ET, Shaltout HA, O'Shea TM, Washburn LK. Renal function and blood pressure are altered in adolescents born preterm. Pediatr Nephrol. 2019 01; 34(1):137-144. PMID: 30112655.
      Citations:    
    43. Wagoner AL, Tarbell SE, Shaltout HA, Diz DI, Weese-Mayer DE, Fortunato JE. Chronic nausea and orthostatic intolerance: Diagnostic utility of orthostatic challenge duration, Nausea Profile Questionnaire, and neurohumoral measures. Neurogastroenterol Motil. 2018 11; 30(11):e13433. PMID: 30101470.
      Citations:    
    44. Shaltout HA, Lee SW, Tegeler CL, Hirsch JR, Simpson SL, Gerdes L, Tegeler CH. Improvements in Heart Rate Variability, Baroreflex Sensitivity, and Sleep After Use of Closed-Loop Allostatic Neurotechnology by a Heterogeneous Cohort. Front Public Health. 2018; 6:116. PMID: 29922641.
      Citations:    
    45. Alexa S. Hendricks, Hossam A. Shaltout, Mark C. Chappell, Debra I. Diz. Central Effects of Angiotensin-(1-7) Treatment on Medullary MAPK and PI3K Pathways of Antenatal Glucocorticoid Exposed Adult Sheep are Sex Dependent. FASEB J. 2018; 32(1):697.3. View Publication.
    46. Andrew Michael South, Patricia A. Nixon, Mark C. Chappell, Debra I. Diz, Elizabeth T. Jensen, Hossam A. Shaltout, Lisa K. Washburn. Preterm Adolescents Exhibit Higher Blood Pressure and Sodium Retention with Higher Uric Acid and Differential Circulating Renin-Angiotensin System Expression. FASEB J. 2018; 32(1):883.6. View Publication.
    47. Tegeler CL, Gerdes L, Shaltout HA, Cook JF, Simpson SL, Lee SW, Tegeler CH. Successful use of closed-loop allostatic neurotechnology for post-traumatic stress symptoms in military personnel: self-reported and autonomic improvements. Mil Med Res. 2017 12 22; 4(1):38. PMID: 29502530.
      Citations:    
    48. Hossam A Shaltout, Catherine L Tegeler, Charles H Tegeler. Use of a Noninvasive, Closed-loop, Allostatic, Neurotechnology Reduced Blood Pressure and Improved Heart Rate Variability in a Pre-hypertensive Cohort. Hypertension. 2017; 70(Suppl_1):AP485. View Publication.
    49. Catherine L Tegeler, Hossam A Shaltout, Lindsay J Howard, Krystal D Schmidt, Emillee I Garlin, Charles H Tegeler. Improved Heart Rate Variability, and Symptoms of Insomnia and Stress, With Use of a Closed-loop, Allostatic Neurotechnology in Law Enforcement Officers. Hypertension. 2017; 70(Suppl_1):AP484. View Publication.
    50. Charles H Tegeler, Catherine L Tegeler, Hossam A Shaltout. Healing a Broken Heart Using a Closed-loop, Allostatic, Neurotechnology: A Case Study in a Patient Suffering From Takotsubo Syndrome. Hypertension. 2017; 70(Suppl_1):AP483. View Publication.
    51. Chris L Schaich, Hossam A Shaltout, Alex Kovach, Megan Grabenauer, Brian F Thomas, Tina E Brinkley, Barbara J Nicklas, Debra I Diz. Gender-specific Relationships Between Plasma Levels of Endocannabinoids and Vagal and Sympathetic Control of Heart Rate in Normotensive Obese Older Adults. Hypertension. 2017; 70(Suppl_1):AP204. View Publication.
    52. Andrew M South, Patricia A Nixon, Mark C Chappell, Debra I Diz, Gregory B Russell, Elizabeth T Jensen, Hossam A Shaltout, Lisa K Washburn. Obesity and Alterations in Renal Function in Adolescents Born Preterm With Very Low Birth Weight. Hypertension. 2017; 70(Suppl_1):AP123. View Publication.
    53. Alexa S Hendricks, Hossam A Shaltout, Mark C Chappell, Debra I Diz. Central Angiotensin-(1-7) Treatment Attenuates ERK 1/2 Expression and Oxidative Stress in the Dorsal Medulla of Betamethasone-Exposed Sheep That Associates With Improved Blood Pressure and Baroreflex Sensitivity. Hypertension. 2017; 70(Suppl_1):A145. View Publication.
    54. Andrew M South, Patricia A Nixon, Mark C Chappell, Debra I Diz, Gregory B Russell, Elizabeth T Jensen, Hossam A Shaltout, Lisa K Washburn. Influence of Sex and Obesity on the Effect of Preterm Birth on the Renin-angiotensin System in Adolescents. Hypertension. 2017; 70(Suppl_1):A051. View Publication.
    55. Elzahhar PA, Elkazaz S, Soliman R, El-Tombary AA, Shaltout HA, El-Ashmawy IM, Abdel Wahab AE, El-Hawash SA. Design and synthesis of some new 2,3'-bipyridine-5-carbonitriles as potential anti-inflammatory/antimicrobial agents. Future Med Chem. 2017 08; 9(12):1413-1450. PMID: 28771047.
      Citations:    
    56. Washburn LK, Nixon PA, Snively BM, Russell GB, Shaltout HA, South AM, O'Shea TM. Antenatal corticosteroids and cardiometabolic outcomes in adolescents born with very low birth weight. Pediatr Res. 2017 Oct; 82(4):697-703. PMID: 28574979.
      Citations:    
    57. Shaltout HA, Eggebeen J, Marsh AP, Brubaker PH, Laurienti PJ, Burdette JH, Basu S, Morgan A, Dos Santos PC, Norris JL, Morgan TM, Miller GD, Rejeski WJ, Hawfield AT, Diz DI, Becton JT, Kim-Shapiro DB, Kitzman DW. Effects of supervised exercise and dietary nitrate in older adults with controlled hypertension and/or heart failure with preserved ejection fraction. Nitric Oxide. 2017 Sep 30; 69:78-90. PMID: 28549665.
      Citations:    
    58. Tegeler CH, Cook JF, Tegeler CL, Hirsch JR, Shaltout HA, Simpson SL, Fidali BC, Gerdes L, Lee SW. Clinical, hemispheric, and autonomic changes associated with use of closed-loop, allostatic neurotechnology by a case series of individuals with self-reported symptoms of post-traumatic stress. BMC Psychiatry. 2017 04 19; 17(1):141. PMID: 28420362.
      Citations:    
    59. South AM, Nixon PA, Chappell MC, Diz DI, Russell GB, Snively BM, Shaltout HA, Rose JC, O'Shea TM, Washburn LK. Antenatal corticosteroids and the renin-angiotensin-aldosterone system in adolescents born preterm. Pediatr Res. 2017 01; 81(1-1):88-93. PMID: 27636897.
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    60. Nixon PA, Washburn LK, Michael O'Shea T, Shaltout HA, Russell GB, Snively BM, Rose JC. Antenatal steroid exposure and heart rate variability in adolescents born with very low birth weight. Pediatr Res. 2017 01; 81(1-1):57-62. PMID: 27632775.
      Citations:    
    61. Tegeler CH, Tegeler CL, Cook JF, Lee SW, Gerdes L, Shaltout HA, Miles CM, Simpson SL. A Preliminary Study of the Effectiveness of an Allostatic, Closed-Loop, Acoustic Stimulation Neurotechnology in the Treatment of Athletes with Persisting Post-concussion Symptoms. Sports Med Open. 2016 Dec; 2(1):39. PMID: 27747793.
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    62. Yamaleyeva LM, Shaltout HA, Varagic J. Apelin-13 in blood pressure regulation and cardiovascular disease. Curr Opin Nephrol Hypertens. 2016 09; 25(5):396-403. PMID: 27258138.
      Citations:    
    63. Schaich CL, Grabenauer M, Thomas BF, Shaltout HA, Gallagher PE, Howlett AC, Diz DI. Medullary Endocannabinoids Contribute to the Differential Resting Baroreflex Sensitivity in Rats with Altered Brain Renin-Angiotensin System Expression. Front Physiol. 2016; 7:207. PMID: 27375489.
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    64. Chappell MC, Wilson BA, Marshall AC, Azayadneh E, Rose JC, Diz DI and Shaltout HA. The ACE2 – Angiotensin (1-7)-Mas Receptor Axis in the Kidney. In: New Aspects of the Renin Angiotensin System in Cardiovascular and Renal Diseases. Bentham Science Publishers. 2016; 194-216. View Publication.
    65. Fortunato JE, Tegeler CL, Gerdes L, Lee SW, Pajewski NM, Franco ME, Cook JF, Shaltout HA, Tegeler CH. Use of an allostatic neurotechnology by adolescents with postural orthostatic tachycardia syndrome (POTS) is associated with improvements in heart rate variability and changes in temporal lobe electrical activity. Exp Brain Res. 2016 Mar; 234(3):791-8. PMID: 26645307.
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    66. Wagoner AL, Shaltout HA, Fortunato JE, Diz DI. Distinct neurohumoral biomarker profiles in children with hemodynamically defined orthostatic intolerance may predict treatment options. . 2016 Feb 01; 310(3):H416-25. PMID: 26608337.
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    67. Jefferson ME, Nicklas BJ, Chmelo EA, Crotts CI, Shaltout HA, Diz DI, Marsh AP, Brinkley TE. Effects of Resistance Training With and Without Caloric Restriction on Arterial Stiffness in Overweight and Obese Older Adults. Am J Hypertens. 2016 Apr; 29(4):494-500. PMID: 26297029.
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    68. Schaich CL, Shaltout HA, Grabenauer M, Thomas BF, Gallagher PE, Howlett AC, Diz DI. Alterations in the Medullary Endocannabinoid System Contribute to Age-related Impairment of Baroreflex Sensitivity. J Cardiovasc Pharmacol. 2015 May; 65(5):473-9. PMID: 25636077.
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    69. Tegeler CH, Shaltout HA, Tegeler CL, Gerdes L, Lee SW. Rightward dominance in temporal high-frequency electrical asymmetry corresponds to higher resting heart rate and lower baroreflex sensitivity in a heterogeneous population. Brain Behav. 2015 Jun; 5(6):e00343. PMID: 26085968.
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    70. El-Bassossy HM, Shaltout HA. Allopurinol alleviates hypertension and proteinuria in high fructose, high salt and high fat induced model of metabolic syndrome. Transl Res. 2015 May; 165(5):621-30. PMID: 25528722.
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    71. Lee SW, Gerdes L, Tegeler CL, Shaltout HA, Tegeler CH. A bihemispheric autonomic model for traumatic stress effects on health and behavior. Front Psychol. 2014; 5:843. PMID: 25136325.
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    72. Schaich CL, Shaltout HA, Brosnihan KB, Howlett AC, Diz DI. Acute and chronic systemic CB1 cannabinoid receptor blockade improves blood pressure regulation and metabolic profile in hypertensive (mRen2)27 rats. Physiol Rep. 2014 Aug 01; 2(8). PMID: 25168868.
      Citations:    
    73. Fortunato JE, Wagoner AL, Harbinson RL, D'Agostino RB, Shaltout HA, Diz DI. Effect of fludrocortisone acetate on chronic unexplained nausea and abdominal pain in children with orthostatic intolerance. J Pediatr Gastroenterol Nutr. 2014 Jul; 59(1):39-43. PMID: 25222805.
      Citations:    
    74. Tarbell SE, Shaltout HA, Wagoner AL, Diz DI, Fortunato JE. Relationship among nausea, anxiety, and orthostatic symptoms in pediatric patients with chronic unexplained nausea. Exp Brain Res. 2014 Aug; 232(8):2645-50. PMID: 24829068.
      Citations:    
    75. Tegeler CH, Lee SW, Shaltout HA. Significance of right anterior insula activity for mental health intervention. JAMA Psychiatry. 2014 Mar; 71(3):336. PMID: 24599239.
      Citations:    
    76. Chappell MC, Marshall AC, Alzayadneh EM, Shaltout HA, Diz DI. Update on the Angiotensin converting enzyme 2-Angiotensin (1-7)-MAS receptor axis: fetal programing, sex differences, and intracellular pathways. Front Endocrinol (Lausanne). 2014 Jan 09; 4:201. PMID: 24409169.
      Citations:    
    77. Marshall AC, Shaltout HA, Pirro NT, Rose JC, Diz DI, Chappell MC. Enhanced activity of an angiotensin-(1-7) neuropeptidase in glucocorticoid-induced fetal programming. Peptides. 2014 Feb; 52:74-81. PMID: 24355101.
      Citations:    
    78. Marshall AC, Shaltout HA, Pirro NT, Rose JC, Diz DI, Chappell MC. Antenatal betamethasone exposure is associated with lower ANG-(1-7) and increased ACE in the CSF of adult sheep. . 2013 Oct 01; 305(7):R679-88. PMID: 23948771.
      Citations:    
    79. Marshall AC, Shaltout HA, Nautiyal M, Rose JC, Chappell MC, Diz DI. Fetal betamethasone exposure attenuates angiotensin-(1-7)-Mas receptor expression in the dorsal medulla of adult sheep. Peptides. 2013 Jun; 44:25-31. PMID: 23538211.
      Citations:    
    80. Nautiyal M, Shaltout HA, de Lima DC, do Nascimento K, Chappell MC, Diz DI. Response to Angiotensin-(1-7) and Bradykinin in Baroreceptor Reflex Sensitivity in Hypertension. Hypertension. 2013 Feb; 61(2):e20. PMID: 23444463.
      Citations:    
    81. Nautiyal M, Shaltout HA, de Lima DC, do Nascimento K, Chappell MC, Diz DI. Central angiotensin-(1-7) improves vagal function independent of blood pressure in hypertensive (mRen2)27 rats. Hypertension. 2012 Nov; 60(5):1257-65. PMID: 23045456.
      Citations:    
    82. Garcia-Espinosa MA, Shaltout HA, Gallagher PE, Chappell MC, Diz DI. In vivo expression of angiotensin-(1-7) lowers blood pressure and improves baroreflex function in transgenic (mRen2)27 rats. J Cardiovasc Pharmacol. 2012 Aug; 60(2):150-7. PMID: 22526299.
      Citations:    
    83. Shaltout HA, Tooze JA, Rosenberger E, Kemper KJ. Time, touch, and compassion: effects on autonomic nervous system and well-being. Explore (NY). 2012 May-Jun; 8(3):177-84. PMID: 22560756.
      Citations:    
    84. Shaltout HA, Rose JC, Chappell MC, Diz DI. Angiotensin-(1-7) deficiency and baroreflex impairment precede the antenatal Betamethasone exposure-induced elevation in blood pressure. Hypertension. 2012 Feb; 59(2):453-8. PMID: 22215705.
      Citations:    
    85. Kemper KJ, Shaltout HA. Non-verbal communication of compassion: measuring psychophysiologic effects. BMC Complement Altern Med. 2011 Dec 20; 11:132. PMID: 22185349.
      Citations:    
    86. Logan EM, Aileru AA, Shaltout HA, Averill DB, Diz DI. The functional role of PI3K in maintenance of blood pressure and baroreflex suppression in (mRen2)27 and mRen2.Lewis rat. J Cardiovasc Pharmacol. 2011 Oct; 58(4):367-73. PMID: 21697727.
      Citations:    
    87. Fortunato JE, Shaltout HA, Larkin MM, Rowe PC, Diz DI, Koch KL. Fludrocortisone improves nausea in children with orthostatic intolerance (OI). Clin Auton Res. 2011 Dec; 21(6):419-23. PMID: 21796356.
      Citations:    
    88. Arnold AC, Shaltout HA, Gilliam-Davis S, Kock ND, Diz DI. Autonomic control of the heart is altered in Sprague-Dawley rats with spontaneous hydronephrosis. . 2011 Jun; 300(6):H2206-13. PMID: 21460193.
      Citations:    
    89. Shaltout HA, Chappell MC, Rose JC, Diz DI. Exaggerated sympathetic mediated responses to behavioral or pharmacological challenges following antenatal betamethasone exposure. Am J Physiol Endocrinol Metab. 2011 Jun; 300(6):E979-85. PMID: 21386063.
      Citations:    
    90. Diz DI, Arnold AC, Nautiyal M, Isa K, Shaltout HA, Tallant EA. Angiotensin peptides and central autonomic regulation. Curr Opin Pharmacol. 2011 Apr; 11(2):131-7. PMID: 21367658.
      Citations:    
    91. Gwathmey TM, Shaltout HA, Rose JC, Diz DI, Chappell MC. Glucocorticoid-induced fetal programming alters the functional complement of angiotensin receptor subtypes within the kidney. Hypertension. 2011 Mar; 57(3):620-6. PMID: 21220702.
      Citations:    
    92. Arnold AC, Isa K, Shaltout HA, Nautiyal M, Ferrario CM, Chappell MC, Diz DI. Angiotensin-(1-12) requires angiotensin converting enzyme and AT1 receptors for cardiovascular actions within the solitary tract nucleus. . 2010 Sep; 299(3):H763-71. PMID: 20562338.
      Citations:    
    93. Shaltout HA, Rose JC, Figueroa JP, Chappell MC, Diz DI, Averill DB. Acute AT(1)-receptor blockade reverses the hemodynamic and baroreflex impairment in adult sheep exposed to antenatal betamethasone. . 2010 Aug; 299(2):H541-7. PMID: 20543085.
      Citations:    
    94. Garcia-Espinosa MA, Shaltout HA, Olson J, Westwood BM, Robbins ME, Link K, Diz DI. Proton magnetic resonance spectroscopy detection of neurotransmitters in dorsomedial medulla correlate with spontaneous baroreceptor reflex function. Hypertension. 2010 Feb; 55(2):487-93. PMID: 20065146.
      Citations:    
    95. Arnold AC, Shaltout HA, Gallagher PE, Diz DI. Leptin impairs cardiovagal baroreflex function at the level of the solitary tract nucleus. Hypertension. 2009 Nov; 54(5):1001-8. PMID: 19770402.
      Citations:    
    96. Gwathmey TM, Shaltout HA, Pendergrass KD, Pirro NT, Figueroa JP, Rose JC, Diz DI, Chappell MC. Nuclear angiotensin II type 2 (AT2) receptors are functionally linked to nitric oxide production. Am J Physiol Renal Physiol. 2009 Jun; 296(6):F1484-93. PMID: 19244399.
      Citations:    
    97. Shaltout HA, Figueroa JP, Rose JC, Diz DI, Chappell MC. Alterations in circulatory and renal angiotensin-converting enzyme and angiotensin-converting enzyme 2 in fetal programmed hypertension. Hypertension. 2009 Feb; 53(2):404-8. PMID: 19047579.
      Citations:    
    98. Shaltout HA, Westwood BM, Averill DB, Ferrario CM, Figueroa JP, Diz DI, Rose JC, Chappell MC. Angiotensin metabolism in renal proximal tubules, urine, and serum of sheep: evidence for ACE2-dependent processing of angiotensin II. Am J Physiol Renal Physiol. 2007 Jan; 292(1):F82-91. PMID: 16896185.
      Citations:    
    99. Shaltout HA, Abdel-Rahman AA. Mechanism of fatty acids induced suppression of cardiovascular reflexes in rats. J Pharmacol Exp Ther. 2005 Sep; 314(3):1328-37. PMID: 15937146.
      Citations:    
    100. Shaltout HA, Abdel-Rahman AA. Cyclosporine induces progressive attenuation of baroreceptor heart rate response and cumulative pressor response in conscious unrestrained rats. J Pharmacol Exp Ther. 2003 Jun; 305(3):966-73. PMID: 12626637.
      Citations:    
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