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Jaime L. Speiser PhD, MSc

TitleAssociate Professor
InstitutionWake Forest School of Medicine
DepartmentPHS-Biostatistics and Data Science (Public Health Sciences)
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Tavabie OD, Karvellas CJ, Salehi S, Speiser JL, Rose CF, Menon K, Prachalias A, Heneghan MA, Agarwal K, Lee WM, McPhail MJW, Aluvihare VR. A novel microRNA-based prognostic model outperforms standard prognostic models in patients with acetaminophen-induced acute liver failure. J Hepatol. 2021 Apr 12. PMID: 33857547.
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    2. Speiser JL, Callahan KE, Houston DK, Fanning J, Gill TM, Guralnik JM, Newman AB, Pahor M, Rejeski WJ, Miller ME. Machine Learning in Aging: An Example of Developing Prediction Models for Serious Fall Injury in Older Adults. J Gerontol A Biol Sci Med Sci. 2021 Mar 31; 76(4):647-654. PMID: 32498077.
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    3. Speiser JL. A random forest method with feature selection for developing medical prediction models with clustered and longitudinal data. J Biomed Inform. 2021 May; 117:103763. PMID: 33781921.
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    4. Usoh CO, Johnson CP, Speiser JL, Bundy R, Dharod A, Aloi JA. Real-World Efficacy of the Hybrid Closed-Loop System. J Diabetes Sci Technol. 2021 Jan 11; 1932296820985103. PMID: 33430621.
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    5. MacDonald AJ, Speiser JL, Ganger DR, Nilles KM, Orandi BJ, Larson AM, Lee WM, Karvellas CJ. Clinical and Neurologic Outcomes in Acetaminophen-Induced Acute Liver Failure: A 21-Year Multicenter Cohort Study. Clin Gastroenterol Hepatol. 2020 Sep 10. PMID: 32920216.
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    6. Ip EH, Chen SH, Bandeen-Roche K, Speiser JL, Cai L, Houston DK. Longitudinal partially ordered data analysis for preclinical sarcopenia. Stat Med. 2020 10 30; 39(24):3313-3328. PMID: 32652653.
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    7. Karvellas CJ, Speiser JL, Tremblay M, Lee WM, Rose CF. Elevated Serum Liver-Type Fatty Acid Binding Protein Levels in Non-acetaminophen Acute Liver Failure Patients with Organ Dysfunction. Dig Dis Sci. 2021 01; 66(1):273-283. PMID: 32125573.
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    8. Sunkara PR, Islam T, Bose A, Rosenthal GE, Chevli P, Jogu H, Tk LA, Huang CC, Chaudhary D, Beekman D, Dutta A, Menon S, Speiser JL. Impact of structured interdisciplinary bedside rounding on patient outcomes at a large academic health centre. BMJ Qual Saf. 2020 07; 29(7):569-575. PMID: 31810994.
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    9. Palakshappa D, Speiser JL, Rosenthal GE, Vitolins MZ. Food Insecurity Is Associated with an Increased Prevalence of Comorbid Medical Conditions in Obese Adults: NHANES 2007-2014. J Gen Intern Med. 2019 08; 34(8):1486-1493. PMID: 31161567.
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    10. Speiser JL, Miller ME, Tooze J, Ip E. A Comparison of Random Forest Variable Selection Methods for Classification Prediction Modeling. Expert Syst Appl. 2019 Nov 15; 134:93-101. PMID: 32968335.
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    11. Speiser JL, Karvellas CJ, Wolf BJ, Chung D, Koch DG, Durkalski VL. Predicting daily outcomes in acetaminophen-induced acute liver failure patients with machine learning techniques. Comput Methods Programs Biomed. 2019 Jul; 175:111-120. PMID: 31104700.
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    12. Speiser JL, Wolf BJ, Chung D, Karvellas CJ, Koch DG, Durkalski VL. BiMM forest: A random forest method for modeling clustered and longitudinal binary outcomes. Chemometr Intell Lab Syst. 2019 Feb 15; 185:122-134. PMID: 31656362.
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    13. Speiser, J; Wolf, B; Chung, D; Karvellas, C; Koch, D; Durkalski, V. BiMM forest: A random forest method for modeling clustered and longitudinal binary outcomes. Chemom Intell Lab Syst. 2019; (185):122-134.
    14. Palakshappa, D; Speiser, J; Rosenthal, G; Vitolins, M. Food insecurity is associated with an increased risk of comorbid medical conditions in obese individuals. J Gen Intern Med. 2019; 1-8.
    15. Speiser, J; Karvellas, C; Wolf, B; Chung, D; Koch, D; Durkalski, V. Predicting daily outcomes in acetaminophen-induced acute liver failure patients with machine learning techniques. Comput Methods Programs Biomed. 2019; 1(175):111-120.
    16. Speiser, J; Miller, M; Tooze, J; Ip, E. A comparison of random forest variable selection methods for classification modeling. Expert Syst Appl. 2019; 134:93-101.
    17. Speiser JL, Karvellas CJ, Shumilak G, Sligl WI, Mirzanejad Y, Gurka D, Kumar A, Kumar A. Predicting in-hospital mortality in pneumonia-associated septic shock patients using a classification and regression tree: a nested cohort study. J Intensive Care. 2018; 6:66. PMID: 30349726.
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    18. Speiser JL, Wolf BJ, Chung D, Karvellas CJ, Koch DG, Durkalski VL. BiMM tree: A decision tree method for modeling clustered and longitudinal binary outcomes. Commun Stat Simul Comput. 2020; 49(4):1004-1023. PMID: 32377032.
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    19. Speiser, J; Wolf, B; Chung, D; Karvellas, C; Koch, D; Durkalski, V. BiMM tree: A decision tree method for modeling clustered and longitudinal binary outcomes. Commun Stat Simul Comput. 2018; 1-20.
    20. Speiser, J; Karvellas, C; Shumilak, G; Sligl, W; Mirzanejad, Y; Gurka, D; Kumar, A; Kumar, A. Predicting in-hospital mortality in pneumonia-associated septic shock patients using a classification and regression tree: A nested cohort study. J Intensive Care. 2018; 1(6):66-67.
    21. Karvellas CJ, Speiser JL, Tremblay M, Lee WM, Rose CF. The association between FABP7 serum levels with survival and neurological complications in acetaminophen-induced acute liver failure: a nested case-control study. Ann Intensive Care. 2017 Oct 05; 7(1):99. PMID: 28983815.
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    22. Karvellas CJ, Speiser JL, Tremblay M, Lee WM, Rose CF. REPLY. Hepatology. 2017 08; 66(2):670-671. PMID: 28370031.
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    23. O'Connell NS, Dai L, Jiang Y, Speiser JL, Ward R, Wei W, Carroll R, Gebregziabher M. Methods for Analysis of Pre-Post Data in Clinical Research: A Comparison of Five Common Methods. J Biom Biostat. 2017 Feb 24; 8(1):1-8. PMID: 30555734.
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    24. Karvellas CJ, Speiser JL, Tremblay M, Lee WM, Rose CF. Elevated FABP1 serum levels are associated with poorer survival in acetaminophen-induced acute liver failure. Hepatology. 2017 03; 65(3):938-949. PMID: 27859489.
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    25. O'Connell, N; Dai, L; Speiser, J; Ward, R; Wei, W; Carroll, R; Gebregziabher, G. Methods for analysis of pre-post data in clinical research: a comparison of five common methods. J Biom Biostat. 2017; 1(8).
    26. Koch, D; Speiser, J; Durkalski, V, et al. The natural history of severe acute liver injury. Am J Gastroenterol. 2017; 9(112):1389-1396.
    27. Kammerdiener LL, Speiser JL, Aquavella JV, Harissi-Dagher M, Dohlman CH, Chodosh J, Ciolino JB. Protective effect of soft contact lenses after Boston keratoprosthesis. Br J Ophthalmol. 2016 Apr; 100(4):549-52. PMID: 26276169.
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    28. Speiser JL, Lee WM, Karvellas CJ. Predicting outcome on admission and post-admission for acetaminophen-induced acute liver failure using classification and regression tree models. PLoS One. 2015; 10(4):e0122929. PMID: 25885260.
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    29. Leonard AP, Cameron RB, Speiser JL, Wolf BJ, Peterson YK, Schnellmann RG, Beeson CC, Rohrer B. Quantitative analysis of mitochondrial morphology and membrane potential in living cells using high-content imaging, machine learning, and morphological binning. Biochim Biophys Acta. 2015 Feb; 1853(2):348-60. PMID: 25447550.
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    30. Speiser JL, Durkalski VL, Lee WM. Random forest classification of etiologies for an orphan disease. Stat Med. 2015 Feb 28; 34(5):887-99. PMID: 25366667.
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