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One or more keywords matched the following items that are connected to Kucera, Gregory
Item TypeName
Academic Article c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for mitoxantrone- and anisomycin-induced apoptosis in HL-60 cells.
Academic Article Influence of the a-ring on the proton affinity and anticancer properties of the prodigiosins.
Academic Article Thermally inert metal ammines as light-inducible DNA-targeted agents. Synthesis, photochemistry, and photobiology of a prototypical rhodium(III)-intercalator conjugate.
Academic Article Synthesis and cytotoxic activity of two novel 1-dodecylthio-2-decyloxypropyl-3-phosphatidic acid conjugates with gemcitabine and cytosine arabinoside.
Academic Article Perillyl alcohol-mediated inhibition of lung cancer cell line proliferation: potential mechanisms for its chemotherapeutic effects.
Academic Article A novel phospholipid gemcitabine conjugate is able to bypass three drug-resistance mechanisms.
Academic Article Lipid nucleoside conjugates for the treatment of cancer.
Academic Article Synthesis, biological activity, and DNA-damage profile of platinum-threading intercalator conjugates designed to target adenine.
Academic Article Cyclooxygenase inhibition and hyperthermia for the potentiation of the cytotoxic response in ovarian cancer cells.
Academic Article Photoinduced cytotoxicity and thioadduct formation by a prodigiosin analogue.
Academic Article Intraperitoneal hyperthermic chemotherapy using carboplatin: a phase I analysis in ovarian carcinoma.
Academic Article A non-cross-linking platinum-acridine agent with potent activity in non-small-cell lung cancer.
Academic Article Using a build-and-click approach for producing structural and functional diversity in DNA-targeted hybrid anticancer agents.
Academic Article Using fluorescent post-labeling to probe the subcellular localization of DNA-targeted platinum anticancer agents.
Academic Article Effect of the diamine nonleaving group in platinum-acridinylthiourea conjugates on DNA damage and cytotoxicity.
Academic Article Tuning the DNA conformational perturbations induced by cytotoxic platinum-acridine bisintercalators: effect of metal cis/trans isomerism and DNA threading groups.
Academic Article Effect of linkage geometry on biological activity in thiourea- and guanidine-substituted acridines and platinum-acridines.
Academic Article Synthesis and biological evaluation of platinum-acridine hybrid agents modified with bipyridine non-leaving groups.
Academic Article Gold(I) analogues of a platinum-acridine antitumor agent are only moderately cytotoxic but show potent activity against Mycobacterium tuberculosis.
Academic Article Probing platinum-adenine-n3 adduct formation with DNA minor-groove binding agents.
Academic Article Analysis of the DNA damage produced by a platinum-acridine antitumor agent and its effects in NCI-H460 lung cancer cells.
Academic Article Synthesis, aqueous reactivity, and biological evaluation of carboxylic acid ester-functionalized platinum-acridine hybrid anticancer agents.
Academic Article Design of a platinum-acridine-endoxifen conjugate targeted at hormone-dependent breast cancer.
Concept Doxorubicin
Concept Down-Regulation
Concept Cattle
Concept DNA, Bacterial
Concept Drug Screening Assays, Antitumor
Concept Escherichia coli
Concept Vero Cells
Concept Carcinoma, Non-Small-Cell Lung
Concept Caspases
Concept Cell Cycle
Concept Crystallography, X-Ray
Concept Esters
Concept HL-60 Cells
Concept Gold
Concept Cisplatin
Concept Antineoplastic Agents
Concept Blotting, Western
Concept Tumor Cells, Cultured
Concept Caspase 3
Concept Cell-Free System
Concept Valproic Acid
Concept Flavonoids
Concept Mitogen-Activated Protein Kinase 3
Concept Adenocarcinoma
Concept Dinoprostone
Concept Rhodium
Concept Carboxylic Acids
Concept Genes, ras
Concept Paraffin Embedding
Concept Enzyme Activation
Concept Genes, Neoplasm
Concept Infusions, Parenteral
Concept Coordination Complexes
Concept Genes, p53
Concept Drug Synergism
Concept Antineoplastic Agents, Hormonal
Concept Signal Transduction
Concept Cell Proliferation
Concept Apoptosis
Concept Platinum
Concept Mycobacterium tuberculosis
Concept Tissue Fixation
Concept Flow Cytometry
Concept Cell Division
Concept Drug Design
Concept Fluorescent Dyes
Concept Philadelphia Chromosome
Concept Cell Survival
Concept Cytarabine
Concept DNA Fragmentation
Concept Carcinoma, Squamous Cell
Concept Antimetabolites, Antineoplastic
Concept Chelating Agents
Concept Antitubercular Agents
Concept Taxoids
Concept Cell Line
Concept Buffers
Concept 2,2'-Dipyridyl
Concept Deoxycytidine
Concept Base Sequence
Concept Receptors, Estrogen
Concept Cell Line, Tumor
Concept Molecular Sequence Data
Concept DNA Cleavage
Academic Article Investigating the cellular fate of a DNA-targeted platinum-based anticancer agent by orthogonal double-click chemistry.
Academic Article Redesigning the DNA-targeted chromophore in platinum-acridine anticancer agents: a structure-activity relationship study.
Academic Article Design of enzymatically cleavable prodrugs of a potent platinum-containing anticancer agent.
Academic Article Synthesis, reactivity, and biological activity of gold(I) complexes modified with thiourea-functionalized tyrosine kinase inhibitors.
Academic Article Improving nucleoside analogs via lipid conjugation: Is fatter any better?
Academic Article Inhibition of DNA Synthesis by a Platinum-Acridine Hybrid Agent Leads to Potent Cell Kill in Non-Small Cell Lung Cancer.
Academic Article Unusual Reactivity of a Potent Platinum-Acridine Hybrid Antitumor Agent.
Academic Article The novel phospholipid mimetic KPC34 is highly active against preclinical models of Philadelphia chromosome positive acute lymphoblastic leukemia.
Academic Article Dissecting intratumoral myeloid cell plasticity by single cell RNA-seq.
Academic Article Optimization of Tissue Microarrays from Banked Human Formalin-Fixed Paraffin Embedded Tissues in the Cancer Research Setting.
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