Platelet Glycoprotein GPIb-IX Complex
"Platelet Glycoprotein GPIb-IX Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides, GPIb alpha, GPIb beta, and GPIX. Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin. Congenital deficiency of the GPIb-IX complex results in Bernard-Soulier syndrome. The platelet glycoprotein GPV associates with GPIb-IX and is also absent in Bernard-Soulier syndrome.
| Descriptor ID |
D019038
|
| MeSH Number(s) |
D12.776.395.550.625.460 D12.776.395.550.625.800.780 D12.776.543.550.625.460 D12.776.543.550.625.800.780 D12.776.543.750.705.675.568
|
| Concept/Terms |
CD42d Antigen- CD42d Antigen
- Antigen, CD42d
- CD42d Antigens
- Antigens, CD42d
CD42b Antigens- CD42b Antigens
- Glycoprotein Ib alpha
- CD42b Antigen
- Antigen, CD42b
- Antigens, CD42b
CD42c Antigens- CD42c Antigens
- Glycoprotein Ib beta
- CD42c Antigen
- Antigen, CD42c
- Antigens, CD42c
|
Below are MeSH descriptors whose meaning is more general than "Platelet Glycoprotein GPIb-IX Complex".
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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