"Integrin alpha2beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.
| Descriptor ID |
D038982
|
| MeSH Number(s) |
D12.776.395.550.625.298 D12.776.543.550.625.298 D12.776.543.750.072.200 D12.776.543.750.705.408.530.249 D12.776.543.750.705.408.850.199 D12.776.543.750.705.675.352 D12.776.543.750.705.876.280
|
| Concept/Terms |
Integrin alpha2beta1- Integrin alpha2beta1
- alpha2beta1, Integrin
- VLA-2
- VLA 2
- Glycoprotein Ia-IIa
- Glycoprotein Ia IIa
- alpha2beta1Integrin
- Very Late Antigen-2
- Late Antigen-2, Very
- Very Late Antigen 2
- CD49b-CD29
- CD49b CD29
- Platelet Membrane Glycoprotein Heterodimer Ia-IIa
- Platelet Membrane Glycoprotein Heterodimer Ia IIa
|
Below are MeSH descriptors whose meaning is more general than "Integrin alpha2beta1".
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