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Linda C. McPhail

TitleProfessor Emeritus of Biochemistry, Winston-Salem
InstitutionWake Forest School of Medicine
DepartmentBiochemistry, Winston-Salem
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Liu TF, Brown CM, El Gazzar M, McPhail L, Millet P, Rao A, Vachharajani VT, Yoza BK, McCall CE. Fueling the flame: bioenergy couples metabolism and inflammation. J Leukoc Biol. 2012 Sep; 92(3):499-507. PMID: 22571857.
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    2. Davis NY, McPhail LC, Horita DA. The NOXO1ß PX domain preferentially targets PtdIns(4,5)P2 and PtdIns(3,4,5)P3. J Mol Biol. 2012 Apr 13; 417(5):440-53. PMID: 22342885.
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    3. Mishra M, Byrd MS, Sergeant S, Azad AK, Parsek MR, McPhail L, Schlesinger LS, Wozniak DJ. Pseudomonas aeruginosa Psl polysaccharide reduces neutrophil phagocytosis and the oxidative response by limiting complement-mediated opsonization. Cell Microbiol. 2012 Jan; 14(1):95-106. PMID: 21951860.
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    4. Davis NY, McPhail LC, Horita DA. Backbone 1H, 15N, and 13C resonance assignments for the NOXO1ß PX domain. Biomol NMR Assign. 2011 Oct; 5(2):139-41. PMID: 21188560.
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    5. Lewis EM, Sergeant S, Ledford B, Stull N, Dinauer MC, McPhail LC. Phosphorylation of p22phox on threonine 147 enhances NADPH oxidase activity by promoting p47phox binding. J Biol Chem. 2010 Jan 29; 285(5):2959-67. PMID: 19948736.
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    6. Lewis EM, Singla M, Sergeant S, Koty PP, McPhail LC. X-linked chronic granulomatous disease secondary to skewed X chromosome inactivation in a female with a novel CYBB mutation and late presentation. Clin Immunol. 2008 Nov; 129(2):372-80. PMID: 18774749.
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    7. Shen K, Sergeant S, Hantgan RR, McPhail LC, Horita DA. Mutations in the PX-SH3A linker of p47phox decouple PI(3,4)P2 binding from NADPH oxidase activation. Biochemistry. 2008 Aug 26; 47(34):8855-65. PMID: 18672905.
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    8. Chial HJ, Wu R, Ustach CV, McPhail LC, Mobley WC, Chen YQ. Membrane targeting by APPL1 and APPL2: dynamic scaffolds that oligomerize and bind phosphoinositides. Traffic. 2008 Feb; 9(2):215-29. PMID: 18034774.
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    9. Taylor RM, Lord CI, Riesselman MH, Gripentrog JM, Leto TL, McPhail LC, Berdichevsky Y, Pick E, Jesaitis AJ. Characterization of surface structure and p47phox SH3 domain-mediated conformational changes for human neutrophil flavocytochrome b. Biochemistry. 2007 Dec 11; 46(49):14291-304. PMID: 18004884.
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    10. Lehman N, Ledford B, Di Fulvio M, Frondorf K, McPhail LC, Gomez-Cambronero J. Phospholipase D2-derived phosphatidic acid binds to and activates ribosomal p70 S6 kinase independently of mTOR. FASEB J. 2007 Apr; 21(4):1075-87. PMID: 17242159.
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    11. Sergeant S, McPhail LC. Measurement of phospholipid metabolism in intact neutrophils. Methods Mol Biol. 2007; 412:69-83. PMID: 18453106.
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    12. Taylor RM, Foubert TR, Burritt JB, Baniulis D, McPhail LC, Jesaitis AJ. Anionic amphiphile and phospholipid-induced conformational changes in human neutrophil flavocytochrome b observed by fluorescence resonance energy transfer. Biochim Biophys Acta. 2004 May 27; 1663(1-2):201-13. PMID: 15157622.
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    13. Price MO, McPhail LC, Lambeth JD, Han CH, Knaus UG, Dinauer MC. Creation of a genetic system for analysis of the phagocyte respiratory burst: high-level reconstitution of the NADPH oxidase in a nonhematopoietic system. Blood. 2002 Apr 15; 99(8):2653-61. PMID: 11929750.
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    14. Dechatelet LR, Shirley PS, Wang P, McPhail LC, Gusdon JP. Effects of promethazine hydrochloride on the metabolism of rabbit alveolar macrophages. . 1976 Dec; 153(3):392-5. PMID: 1013149.
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