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Baisong Lu PhD

TitleAssociate Professor
InstitutionWake Forest School of Medicine
DepartmentWake Forest Institute for Regenerative Medicine
Address
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    R01HD058058     (LU, BAISONG)Jul 27, 2009 - Jun 30, 2012
    NIH
    Mitochondrial generation of superoxide in male reproduction
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lu Z, Yao X, Lyu P, Yadav M, Yoo K, Atala A, Lu B. Lentiviral Capsid-Mediated Streptococcus pyogenes Cas9 Ribonucleoprotein Delivery for Efficient and Safe Multiplex Genome Editing. CRISPR J. 2021 Mar 16. PMID: 33733873.
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    2. Yao X, Lyu P, Yoo K, Yadav MK, Singh R, Atala A, Lu B. Engineered extracellular vesicles as versatile ribonucleoprotein delivery vehicles for efficient and safe CRISPR genome editing. J Extracell Vesicles. 2021 Mar; 10(5):e12076. PMID: 33747370.
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    3. Gonzalez-Armenta JL, Li N, Lee RL, Lu B, Molina AJA. Heterochronic Parabiosis: Old Blood Induces Changes in Mitochondrial Structure and Function of Young Mice. J Gerontol A Biol Sci Med Sci. 2021 Feb 25; 76(3):434-439. PMID: 33377482.
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    4. Lyu P, Lu Z, Cho SI, Yadav M, Yoo KW, Atala A, Kim JS, Lu B. Adenine Base Editor Ribonucleoproteins Delivered by Lentivirus-Like Particles Show High On-Target Base Editing and Undetectable RNA Off-Target Activities. CRISPR J. 2021 Feb; 4(1):69-81. PMID: 33616436.
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    5. Lu Z, Priya Rajan SA, Song Q, Zhao Y, Wan M, Aleman J, Skardal A, Bishop C, Atala A, Lu B. 3D scaffold-free microlivers with drug metabolic function generated by lineage-reprogrammed hepatocytes from human fibroblasts. Biomaterials. 2021 02; 269:120668. PMID: 33461059.
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    6. Lyu P, Yoo KW, Yadav MK, Atala A, Aartsma-Rus A, Putten MV, Duan D, Lu B. Sensitive and reliable evaluation of single-cut sgRNAs to restore dystrophin by a GFP-reporter assay. PLoS One. 2020; 15(9):e0239468. PMID: 32970732.
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    7. Javidi-Parsijani P, Lyu P, Makani V, Sarhan WM, Yoo KW, El-Korashi L, Atala A, Lu B. CRISPR/Cas9 increases mitotic gene conversion in human cells. Gene Ther. 2020 06; 27(6):281-296. PMID: 32020049.
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    8. Lyu P, Javidi-Parsijani P, Atala A, Lu B. Delivering Cas9/sgRNA ribonucleoprotein (RNP) by lentiviral capsid-based bionanoparticles for efficient 'hit-and-run' genome editing. Nucleic Acids Res. 2019 09 26; 47(17):e99. PMID: 31299082.
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    9. Lu B, Javidi-Parsijani P, Makani V, Mehraein-Ghomi F, Sarhan WM, Sun D, Yoo KW, Atala ZP, Lyu P, Atala A. Delivering SaCas9 mRNA by lentivirus-like bionanoparticles for transient expression and efficient genome editing. Nucleic Acids Res. 2019 05 07; 47(8):e44. PMID: 30759231.
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    10. Yoo KW, Li N, Makani V, Singh RN, Atala A, Lu B. Large-Scale Preparation of Extracellular Vesicles Enriched with Specific microRNA. Tissue Eng Part C Methods. 2018 11; 24(11):637-644. PMID: 30306827.
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    11. Jiang Y, Liu C, Lei B, Xu X, Lu B. Mitochondria-targeted antioxidant SkQ1 improves spermatogenesis in Immp2l mutant mice. Andrologia. 2018 Mar; 50(2). PMID: 28703400.
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    12. Javidi-Parsijani P, Niu G, Davis M, Lu P, Atala A, Lu B. No evidence of genome editing activity from Natronobacterium gregoryi Argonaute (NgAgo) in human cells. PLoS One. 2017; 12(5):e0177444. PMID: 28494027.
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    13. Li X, Li Y, Liu C, Jin M, Lu B. Oocyte-Specific Expression of Mouse MEX3C652AA in the Ovary and Its Potential Role in Regulating Maternal Fos mRNA. Biol Reprod. 2016 05; 94(5):115. PMID: 27053362.
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    14. Pan C, Jia W, Lu B, Bishop CE. Expression of TAT recombinant Oct4, Sox2, Lin28, and Nanog proteins from baculovirus-infected Sf9 insect cells. Gene. 2015 Feb 10; 556(2):245-8. PMID: 25476026.
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    15. Bharadwaj MS, Zhou Y, Molina AJ, Criswell T, Lu B. Examination of bioenergetic function in the inner mitochondrial membrane peptidase 2-like (Immp2l) mutant mice. Redox Biol. 2014; 2:1008-15. PMID: 25460737.
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    16. Han C, Jiao Y, Zhao Q, Lu B. Mex3c mutation reduces adiposity partially through increasing physical activity. J Endocrinol. 2014 Jun; 221(3):457-68. PMID: 24741071.
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    17. Lu B, Atala A. Small molecules and small molecule drugs in regenerative medicine. Drug Discov Today. 2014 Jun; 19(6):801-8. PMID: 24252867.
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    18. Han C, Zhao Q, Lu B. The role of nitric oxide signaling in food intake; insights from the inner mitochondrial membrane peptidase 2 mutant mice. Redox Biol. 2013; 1:498-507. PMID: 24251118.
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    19. Hicks AN, Lorenzetti D, Gilley J, Lu B, Andersson KE, Miligan C, Overbeek PA, Oppenheim R, Bishop CE. Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo. PLoS One. 2012; 7(10):e47869. PMID: 23082226.
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    20. Jiao Y, George SK, Zhao Q, Hulver MW, Hutson SM, Bishop CE, Lu B. Mex3c mutation reduces adiposity and increases energy expenditure. Mol Cell Biol. 2012 Nov; 32(21):4350-62. PMID: 22927639.
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    21. Zhao Q, Lu B, George SK, Yoo JJ, Atala A. Safeguarding pluripotent stem cells for cell therapy with a non-viral, non-integrating episomal suicide construct. Biomaterials. 2012 Oct; 33(29):7261-71. PMID: 22795541.
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    22. George SK, Jiao Y, Bishop CE, Lu B. Oxidative stress is involved in age-dependent spermatogenic damage of Immp2l mutant mice. Free Radic Biol Med. 2012 Jun 1-15; 52(11-12):2223-33. PMID: 22569411.
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    23. Jiao Y, Bishop CE, Lu B. Mex3c regulates insulin-like growth factor 1 (IGF1) expression and promotes postnatal growth. Mol Biol Cell. 2012 Apr; 23(8):1404-13. PMID: 22357625.
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    24. George SK, Jiao Y, Bishop CE, Lu B. Mitochondrial peptidase IMMP2L mutation causes early onset of age-associated disorders and impairs adult stem cell self-renewal. Aging Cell. 2011 Aug; 10(4):584-94. PMID: 21332923.
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    25. Soler R, Füllhase C, Lu B, Bishop CE, Andersson KE. Bladder dysfunction in a new mutant mouse model with increased superoxide--lack of nitric oxide? J Urol. 2010 Feb; 183(2):780-5. PMID: 20022053.
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    26. Lu B, Poirier C, Gaspar T, Gratzke C, Harrison W, Busija D, Matzuk MM, Andersson KE, Overbeek PA, Bishop CE. A mutation in the inner mitochondrial membrane peptidase 2-like gene (Immp2l) affects mitochondrial function and impairs fertility in mice. Biol Reprod. 2008 Apr; 78(4):601-10. PMID: 18094351.
      Citations:    
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