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One or more keywords matched the following items that are connected to Langefeld, Carl
Item TypeName
Academic Article Genetic linkage and association of Fcgamma receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus.
Academic Article Association of an IL-1A 3'UTR polymorphism with end-stage renal disease and IL-1 alpha expression.
Academic Article Power for genetic association studies with random allele frequencies and genotype distributions.
Academic Article A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity. I. Regulatory FCGR2B polymorphisms and their association with systemic lupus erythematosus.
Academic Article Association analysis of the plasminogen activator inhibitor-1 4G/5G polymorphism in Hispanics and African Americans: the IRAS family study.
Academic Article Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes.
Academic Article Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study.
Academic Article P-selectin gene haplotype associations with albuminuria in the Diabetes Heart Study.
Academic Article Association of protein tyrosine phosphatase-N1 polymorphisms with coronary calcified plaque in the Diabetes Heart Study.
Academic Article The association between innate immunity gene (IRAK1) and C-reactive protein in the Diabetes Heart Study.
Academic Article Associations of adiponectin with body fat distribution and insulin sensitivity in nondiabetic Hispanics and African-Americans.
Academic Article Association of the proprotein convertase subtilisin/kexin-type 2 (PCSK2) gene with type 2 diabetes in an African American population.
Academic Article Comprehensive evaluation of the estrogen receptor alpha gene reveals further evidence for association with type 2 diabetes enriched for nephropathy in an African American population.
Academic Article Association methods in human genetics.
Academic Article Association analysis of the ephrin-B2 gene in African-Americans with end-stage renal disease.
Academic Article Association of polymorphisms in cyclooxygenase (COX)-2 with coronary and carotid calcium in the Diabetes Heart Study.
Academic Article Association of SSTR2 polymorphisms and glucose homeostasis phenotypes: the Insulin Resistance Atherosclerosis Family Study.
Academic Article High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups.
Academic Article Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies.
Academic Article Association of 25-hydroxyvitamin D with blood pressure in predominantly 25-hydroxyvitamin D deficient Hispanic and African Americans.
Academic Article Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD.
Academic Article Chromosome 7p linkage and association study for diabetes related traits and type 2 diabetes in an African-American population enriched for nephropathy.
Academic Article Regional adipose tissue associations with calcified atherosclerotic plaque: African American-diabetes heart study.
Academic Article Genetic factors predisposing to systemic lupus erythematosus and lupus nephritis.
Academic Article Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study.
Academic Article Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans.
Academic Article RGS6 variants are associated with dietary fat intake in Hispanics: the IRAS Family Study.
Academic Article Single-nucleotide polymorphisms in the TNF gene are associated with obesity-related phenotypes in vervet monkeys.
Academic Article Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.
Academic Article Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes.
Academic Article Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.
Academic Article Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21.
Academic Article Genomewide linkage scan for diabetic renal failure and albuminuria: the FIND study.
Academic Article Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes.
Academic Article Meta-analysis of genome-wide linkage scans for renal function traits.
Academic Article Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.
Academic Article Identification of ATPAF1 as a novel candidate gene for asthma in children.
Academic Article Genome-wide association of BMI in African Americans.
Academic Article Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
Academic Article Genetic association and gene-gene interaction analyses in African American dialysis patients with nondiabetic nephropathy.
Academic Article Evaluation of TRAF6 in a large multiancestral lupus cohort.
Academic Article Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap.
Academic Article Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.
Academic Article Immune function genes CD99L2, JARID2 and TPO show association with autism spectrum disorder.
Academic Article Bootstrap aggregating of alternating decision trees to detect sets of SNPs that associate with disease.
Academic Article Brief report: enrichment of associations in genes with fibrosis, apoptosis, and innate immunity functions with cardiac manifestations of neonatal lupus.
Academic Article Informed conditioning on clinical covariates increases power in case-control association studies.
Academic Article Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study.
Academic Article Nucleotide variation, haplotype structure, and association with end-stage renal disease of the human interleukin-1 gene cluster.
Academic Article Renal artery calcified plaque associations with subclinical renal and cardiovascular disease.
Academic Article Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.
Academic Article Association of the mu-opioid receptor gene with type 2 diabetes mellitus in an African American population.
Academic Article Association of proopiomelanocortin gene polymorphisms with obesity in the IRAS family study.
Academic Article Multilocus and interaction-based genome scan for alcoholism risk factors in Caucasian Americans: the COGA study.
Academic Article Association of alpha2-Heremans-Schmid glycoprotein polymorphisms with subclinical atherosclerosis.
Academic Article Association of the estrogen receptor-alpha gene with the metabolic syndrome and its component traits in African-American families: the Insulin Resistance Atherosclerosis Family Study.
Academic Article Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans.
Academic Article Genetic variation in the CRP promoter: association with systemic lupus erythematosus.
Academic Article Association of the distal region of the ectonucleotide pyrophosphatase/phosphodiesterase 1 gene with type 2 diabetes in an African-American population enriched for nephropathy.
Academic Article Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
Academic Article Association of NOS1AP genetic variants with QT interval duration in families from the Diabetes Heart Study.
Academic Article Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study.
Academic Article Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies.
Academic Article Association of arachidonate 12-lipoxygenase genotype variation and glycemic control with albuminuria in type 2 diabetes.
Academic Article Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease.
Academic Article Association of the Kir6.2 E23K variant with reduced acute insulin response in African-Americans.
Academic Article Genome-wide linkage scan in Gullah-speaking African American families with type 2 diabetes: the Sea Islands Genetic African American Registry (Project SuGAR).
Academic Article Association of adiponectin gene polymorphisms with type 2 diabetes in an African American population enriched for nephropathy.
Academic Article Genome-wide association study and follow-up analysis of adiposity traits in Hispanic Americans: the IRAS Family Study.
Academic Article Association of plasma vitamin D levels with adiposity in Hispanic and African Americans.
Academic Article An algorithm for learning maximum entropy probability models of disease risk that efficiently searches and sparingly encodes multilocus genomic interactions.
Academic Article Evaluation of DLG2 as a positional candidate for disposition index in African-Americans from the IRAS Family Study.
Academic Article Dense mapping of MYH9 localizes the strongest kidney disease associations to the region of introns 13 to 15.
Academic Article Association of polymorphisms in the klotho gene with severity of non-diabetic ESRD in African Americans.
Academic Article Candidate genes for non-diabetic ESRD in African Americans: a genome-wide association study using pooled DNA.
Academic Article Genome-wide association study of vitamin D concentrations in Hispanic Americans: the IRAS family study.
Academic Article Association of trypanolytic ApoL1 variants with kidney disease in African Americans.
Academic Article Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus.
Academic Article The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1.
Academic Article A genome-wide association study for diabetic nephropathy genes in African Americans.
Academic Article Association of PNPLA3 with non-alcoholic fatty liver disease in a minority cohort: the Insulin Resistance Atherosclerosis Family Study.
Academic Article Review of the Diabetes Heart Study (DHS) family of studies: a comprehensively examined sample for genetic and epidemiological studies of type 2 diabetes and its complications.
Academic Article Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus.
Academic Article Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups.
Academic Article Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans.
Academic Article Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus.
Academic Article Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome.
Academic Article Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study.
Academic Article A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap.
Academic Article A genome-wide association search for type 2 diabetes genes in African Americans.
Academic Article Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries.
Academic Article Association of APOL1 variants with mild kidney disease in the first-degree relatives of African American patients with non-diabetic end-stage renal disease.
Academic Article Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus.
Academic Article Genome-wide association study of intracranial aneurysms confirms role of Anril and SOX17 in disease risk.
Academic Article Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans.
Academic Article Association between ADIPOQ SNPs with plasma adiponectin and glucose homeostasis and adiposity phenotypes in the IRAS Family Study.
Concept Genetic Association Studies
Concept Genome-Wide Association Study
Academic Article A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
Academic Article Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
Academic Article Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.
Academic Article Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry.
Academic Article Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.
Academic Article PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes.
Academic Article Variants in adiponectin signaling pathway genes show little association with subclinical CVD in the diabetes heart study.
Academic Article Chromosome 2q31.1 associates with ESRD in women with type 1 diabetes.
Academic Article Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
Academic Article Genetic variants in selenoprotein P plasma 1 gene (SEPP1) are associated with fasting insulin and first phase insulin response in Hispanics.
Academic Article Genetic analysis of adiponectin variation and its association with type 2 diabetes in African Americans.
Academic Article APOL1 associations with nephropathy, atherosclerosis, and all-cause mortality in African Americans with type 2 diabetes.
Academic Article Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
Academic Article Genome-wide family-based linkage analysis of exome chip variants and cardiometabolic risk.
Academic Article Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans.
Academic Article Testing gene-environment interactions in family-based association studies using trait-based ascertained samples.
Academic Article Gene-gene interactions in APOL1-associated nephropathy.
Academic Article A genome-wide search for linkage of estimated glomerular filtration rate (eGFR) in the Family Investigation of Nephropathy and Diabetes (FIND).
Academic Article Analysis of coding variants identified from exome sequencing resources for association with diabetic and non-diabetic nephropathy in African Americans.
Academic Article Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease.
Academic Article Genetic risk score associations with cardiovascular disease and mortality in the Diabetes Heart Study.
Academic Article Complement factor H gene associations with end-stage kidney disease in African Americans.
Academic Article Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage.
Academic Article Heritability and genetic association analysis of cognition in theĀ Diabetes Heart Study.
Academic Article Analysis of common and coding variants with cardiovascular disease in the Diabetes Heart Study.
Academic Article Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
Academic Article The ras responsive transcription factor RREB1 is a novel candidate gene for type 2 diabetes associated end-stage kidney disease.
Academic Article The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
Academic Article A comparison of type 2 diabetes risk allele load between African Americans and European Americans.
Academic Article Infection after intracerebral hemorrhage: risk factors and association with outcomes in the ethnic/racial variations of intracerebral hemorrhage study.
Academic Article Heritability and genetic association analysis of neuroimaging measures in the Diabetes Heart Study.
Academic Article Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease.
Academic Article Lack of Association of the APOL1 G3 Haplotype in African Americans with ESRD.
Academic Article Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium.
Academic Article Analysis of a cardiovascular disease genetic risk score in the Diabetes Heart Study.
Academic Article Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans.
Academic Article Rare Coding Variation and Risk of Intracerebral Hemorrhage.
Academic Article An Islet-Targeted Genome-Wide Association Scan Identifies Novel Genes Implicated in Cytokine-Mediated Islet Stress in Type 2 Diabetes.
Academic Article Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND).
Academic Article Deceased donor multidrug resistance protein 1 and caveolin 1 gene variants may influence allograft survival in kidney transplantation.
Academic Article Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.
Academic Article Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus.
Academic Article A Comprehensive Analysis of Common and Rare Variants to Identify Adiposity Loci in Hispanic Americans: The IRAS Family Study (IRASFS).
Academic Article Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA.
Academic Article Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility.
Academic Article Genetic analysis of advanced glycation end products in the DHS MIND study.
Academic Article Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND).
Academic Article Genome-wide imputation study identifies novel HLA locus for pulmonary fibrosis and potential role for auto-immunity in fibrotic idiopathic interstitial pneumonia.
Academic Article Trans-ethnic Meta-analysis and Functional Annotation Illuminates theĀ Genetic Architecture of Fasting Glucose and Insulin.
Academic Article Mapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity.
Academic Article Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.
Academic Article Genome-Wide Association of CKD Progression: The Chronic Renal Insufficiency Cohort Study.
Academic Article Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation.
Academic Article Analysis of Whole Exome Sequencing with Cardiometabolic Traits Using Family-Based Linkage and Association in the IRAS Family Study.
Academic Article Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications.
Academic Article Genetic variation at 16q24.2 is associated with small vessel stroke.
Academic Article Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.
Academic Article Genome-wide linkage and association analysis of cardiometabolic phenotypes in Hispanic Americans.
Grant Genetic Architecture of Obesity and Inflammation in Hispanic Americans
Grant Genetics of Juvenile Idiopathic Arthritis and Subtypes
Grant Exome Sequencing to Identify CVD Risk Variants in Hispanics & African Americans
Academic Article Genetic epidemiology in kidney disease.
Academic Article Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
Academic Article A genome-wide linkage and association analysis of imputed insertions and deletions with cardiometabolic phenotypes in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study.
Academic Article Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci.
Grant Genetics and the Microbiome in Anti-Ro Preclinical and Established Autoimmunity
Academic Article Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke.
Academic Article Genetic architecture of lipid traits in the Hispanic community health study/study of Latinos.
Academic Article Association of Natural Killer Cell Ligand Polymorphism HLA-C Asn80Lys With the Development of Anti-SSA/Ro-Associated Congenital Heart Block.
Academic Article Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.
Academic Article The African Descent and Glaucoma Evaluation Study (ADAGES) III: Contribution of Genotype to Glaucoma Phenotype in African Americans: Study Design and Baseline Data.
Academic Article Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions.
Academic Article Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations.
Academic Article Exome Sequencing Identifies Genetic Variants Associated with Circulating Lipid Levels in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study (IRASFS).
Academic Article Genome-Wide Study of Subcutaneous and Visceral Adipose Tissue Reveals Novel Sex-Specific Adiposity Loci in Mexican Americans.
Academic Article Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
Academic Article Trans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks.
Academic Article Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans.
Academic Article Association Between Inflammatory Biomarker C-Reactive Protein and Radiotherapy-Induced Early Adverse Skin Reactions in a Multiracial/Ethnic Breast Cancer Population.
Academic Article Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Academic Article A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
Academic Article Genetic Architecture of Primary Open-Angle Glaucoma in Individuals of African Descent: The African Descent and Glaucoma Evaluation Study III.
Academic Article A catalog of genetic loci associated with kidney function from analyses of a million individuals.
Academic Article Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium.
Academic Article Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
Academic Article Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans.
Academic Article Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
Academic Article Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
Academic Article Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Academic Article Novel genetic associations with interferon in systemic lupus erythematosus identified by replication and fine-mapping of trait-stratified genome-wide screen.
Academic Article Genetic influences on susceptibility to rheumatoid arthritis in African-Americans.
Academic Article Association of Apolipoprotein E With Intracerebral Hemorrhage Risk by Race/Ethnicity: A Meta-analysis.
Academic Article Protective association between JC polyoma viruria and kidney disease.
Academic Article Subtype Specificity of Genetic Loci Associated With Stroke in 16?664 Cases and 32?792 Controls.
Academic Article GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.
Academic Article Genome-wide enriched pathway analysis of acute post-radiotherapy pain in breast cancer patients: a prospective cohort study.
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