beta-N-Acetylhexosaminidases
"beta-N-Acetylhexosaminidases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hexosaminidase specific for non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. It acts on GLUCOSIDES; GALACTOSIDES; and several OLIGOSACCHARIDES. Two specific mammalian isoenzymes of beta-N-acetylhexoaminidase are referred to as HEXOSAMINIDASE A and HEXOSAMINIDASE B. Deficiency of the type A isoenzyme causes TAY-SACHS DISEASE, while deficiency of both A and B isozymes causes SANDHOFF DISEASE. The enzyme has also been used as a tumor marker to distinguish between malignant and benign disease.
| Descriptor ID |
D001619
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| MeSH Number(s) |
D08.811.277.450.483.180
|
| Concept/Terms |
beta-N-Acetylhexosaminidases- beta-N-Acetylhexosaminidases
- beta N Acetylhexosaminidases
- N-Acetyl-beta-D-hexosaminidase
- N Acetyl beta D hexosaminidase
- beta-N-Acetyl-hexosaminidase
- beta N Acetyl hexosaminidase
- beta-N-Acetylhexosaminidase
- beta N Acetylhexosaminidase
- beta-Hexosaminidase
- beta Hexosaminidase
- beta-N-Acetyl-D-hexosaminidase
- beta N Acetyl D hexosaminidase
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Below are MeSH descriptors whose meaning is more general than "beta-N-Acetylhexosaminidases".
Below are MeSH descriptors whose meaning is more specific than "beta-N-Acetylhexosaminidases".
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
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