"Antigens, CD40" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. It is found on mature B-LYMPHOCYTES and some EPITHELIAL CELLS, lymphoid DENDRITIC CELLS. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centers. Mutations of the gene for CD40 antigen result in HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 3. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
| Descriptor ID |
D019013
|
| MeSH Number(s) |
D12.776.543.750.705.852.760.097 D23.050.301.264.035.140 D23.050.301.264.051.140 D23.101.100.110.140 D23.101.100.150.140
|
| Concept/Terms |
Antigens, CD40- Antigens, CD40
- CD40 Antigens
- TNFRSF5 Receptor
- Receptor, TNFRSF5
- Tumor Necrosis Factor Receptor Superfamily, Member 5
- CD40 Antigen
- Antigen, CD40
- CDw40 Antigen
- Antigen, CDw40
|
Below are MeSH descriptors whose meaning is more general than "Antigens, CD40".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Tumor Necrosis Factor [D12.776.543.750.705.852.760]
- Antigens, CD40 [D12.776.543.750.705.852.760.097]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, CD [D23.050.301.264.035]
- Antigens, CD40 [D23.050.301.264.035.140]
- Antigens, Differentiation, B-Lymphocyte [D23.050.301.264.051]
- Antigens, CD40 [D23.050.301.264.051.140]
- Biological Markers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, CD [D23.101.100.110]
- Antigens, CD40 [D23.101.100.110.140]
- Antigens, Differentiation, B-Lymphocyte [D23.101.100.150]
- Antigens, CD40 [D23.101.100.150.140]
Below are MeSH descriptors whose meaning is more specific than "Antigens, CD40".
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Below are the most recent publications written about "Antigens, CD40" by people in Profiles.