A hereditary motor and sensory neuropathy transmitted most often as an autosomal dominant trait and characterized by progressive distal wasting and loss of reflexes in the muscles of the legs (and occasionally involving the arms). Onset is usually in the second to fourth decade of life. This condition has been divided into two subtypes, hereditary motor and sensory neuropathy (HMSN) types I and II. HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. (Adams et al., Principles of Neurology, 6th ed, p1343)

Descriptor ID	D002607
MeSH Number(s)	C10.500.300.200 C10.574.500.495.200 C10.668.829.800.300.200 C16.131.666.300.200 C16.320.400.375.200
Concept/Terms	Charcot-Marie-Tooth Disease Charcot-Marie-Tooth Disease Charcot Marie Tooth Disease Peroneal Muscular Atrophy Muscular Atrophy, Peroneal Atrophies, Peroneal Muscular Atrophy, Peroneal Muscular Muscular Atrophies, Peroneal Peroneal Muscular Atrophies Atrophy, Muscular, Peroneal Charcot-Marie Disease Charcot Marie Disease Roussy-Levy Syndrome Roussy-Levy Syndrome Roussy Levy Syndrome Syndrome, Roussy-Levy Roussy-Levy Hereditary Areflexic Dystasia Roussy-Levy Disease Roussy Levy Disease Hereditary Areflexic Dystasia Areflexic Dystasia, Hereditary Areflexic Dystasias, Hereditary Dystasia, Hereditary Areflexic Dystasias, Hereditary Areflexic Hereditary Areflexic Dystasias Roussy Levy Hereditary Areflexic Dystasia Hereditary Type I Motor and Sensory Neuropathy Hereditary Type I Motor and Sensory Neuropathy Hereditary Motor, and Sensory Neuropathy Type I HMN Distal Type I HMSN Type I HMSN Type Is Neuropathy, Type I Hereditary Motor and Sensory Charcot-Marie-Tooth Disease, Type I Charcot Marie Tooth Disease, Type I HMSN I HMSN Is HMSN Type II HMSN Type II HMSN Type IIs HMSN II HMSN IIs Neuropathy, Type II Hereditary Motor and Sensory Charcot-Marie-Tooth Disease, Type II Charcot Marie Tooth Disease, Type II Hereditary Motor and Sensory-Neuropathy Type II Hereditary Motor and Sensory Neuropathy Type II Charcot-Marie-Tooth Disease, Type Ia Charcot-Marie-Tooth Disease, Type Ia Charcot Marie Tooth Disease, Type Ia Charcot-Marie-Tooth Disease, Demyelinating, Type 1A Charcot-Marie-Tooth Disease, Type 1A Charcot Marie Tooth Disease, Type 1A HMSN1a Hereditary Motor and Sensory Neuropathy 1A Hereditary Motor And Sensory Neuropathy Ia HMSN 1A HMSN 1As HMSN Ia Charcot-Marie-Tooth Disease, Autosomal Dominant, With Focally Folded Myelin Sheaths, Type 1a Charcot-Marie-Tooth Neuropathy, Type 1a Charcot Marie Tooth Neuropathy, Type 1a Charcot-Marie-Tooth Disease, Type Ib Charcot-Marie-Tooth Disease, Type Ib Charcot Marie Tooth Disease, Type Ib Charcot-Marie-Tooth Disease, Demyelinating, Type 1B Charcot-Marie-Tooth Disease, Slow Nerve Conduction Type, Linked To Duffy Charcot-Marie-Tooth Disease, Type 1B Charcot Marie Tooth Disease, Type 1B HMSN1b Hereditary Motor and Sensory Neuropathy 1B Hereditary Motor And Sensory Neuropathy I Hereditary Motor And Sensory Neuropathy Ib HMSN 1B HMSN 1Bs HMSN Ib Charcot-Marie-Tooth Disease, Autosomal Dominant, With Focally Folded Myelin Sheaths, Type 1b Charcot-Marie-Tooth Neuropathy, Type 1b Charcot Marie Tooth Neuropathy, Type 1b

Below are MeSH descriptors whose meaning is more general than "Charcot-Marie-Tooth Disease".

Below are MeSH descriptors whose meaning is related to "Charcot-Marie-Tooth Disease".

Below are MeSH descriptors whose meaning is more specific than "Charcot-Marie-Tooth Disease".