An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Descriptor ID	D003550
MeSH Number(s)	C06.689.202 C08.381.187 C16.320.190 C16.614.213
Concept/Terms	Cystic Fibrosis Cystic Fibrosis Fibrosis, Cystic Mucoviscidosis Pulmonary Cystic Fibrosis Pulmonary Cystic Fibrosis Cystic Fibrosis, Pulmonary Pancreatic Cystic Fibrosis Pancreatic Cystic Fibrosis Cystic Fibrosis, Pancreatic Fibrocystic Disease of Pancreas Pancreas Fibrocystic Disease Pancreas Fibrocystic Diseases

Below are MeSH descriptors whose meaning is more general than "Cystic Fibrosis".

Below are MeSH descriptors whose meaning is related to "Cystic Fibrosis".

Below are MeSH descriptors whose meaning is more specific than "Cystic Fibrosis".