"P-Glycoprotein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).
| Descriptor ID |
D020168
|
| MeSH Number(s) |
D12.776.157.530.100.652.500 D12.776.157.530.450.074.500.500.750 D12.776.395.550.020.610.610 D12.776.543.550.192.610.610 D12.776.543.585.100.610.500 D12.776.543.585.450.074.500.500.750
|
| Concept/Terms |
P-Glycoprotein- P-Glycoprotein
- P Glycoprotein
- PGY-1 Protein
- PGY 1 Protein
- Multidrug Resistance Protein 1
- ATP-Binding Cassette, Sub-Family B, Member 1
- P-gp
- MDR1 Protein
|
Below are MeSH descriptors whose meaning is more general than "P-Glycoprotein".
Below are MeSH descriptors whose meaning is more specific than "P-Glycoprotein".
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Below are the most recent publications written about "P-Glycoprotein" by people in Profiles.