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Kiran Kumar Solingapuram Sai PhD

TitleAssociate Professor
InstitutionWake Forest School of Medicine
DepartmentDiagnostic Radiology
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    Other Positions
    TitleAssociate Professor
    InstitutionWake Forest School of Medicine
    DepartmentBiomedical Engineering

    TitleAssociate Professor
    InstitutionWake Forest School of Medicine
    DepartmentTranslational Neuroscience


    Collapse Research 
    Collapse research activities and funding
    1R01AG065839-01     (SOLINGAPURAM SAI, KIRAN)
    NATIONAL INSTITUTE ON AGING
    EVALUATING MICROTUBULE BINDING AS A POTENTIAL IMAGING BIOMARKER FOR ALZHEIMER'S DISEASE
    R21AG089125     (Solingapuram Sai Kiran)
    NIH/NIA
    Developing novel PET radioligands to image GPR39 in Alzheimer's Disease
    Role: PI
    R56AG081860     (Solingapuram Sai, Kiran)
    NIH/NIA
    PET Imaging of microtubules in cognitively normal and impaired older adults
    Role: PI

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kawas MI, Atcheson KM, Flood WC, Sheridan CA, Barcus RA, Flashman LA, McAllister TW, Lipford ME, Kim J, Urban JE, Davenport EM, Vaughan CG, Solingapuram Sai KK, Stitzel JD, Maldjian JA, Whitlow CT. Cognitive and Salience Network Connectivity Changes following a Single Season of Repetitive Head Impact Exposure in High School Football. AJNR Am J Neuroradiol. 2024 Jul 25. PMID: 39054293.
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    2. Krizan I, Solingapuram Sai KK, Damuka N, Macauley SL, Maria Thurman B, Long M, Kavanagh K. Exploratory Dual PET imaging of [18F] fluorodeoxyglucose and [11C]acetoacetate in type 2 diabetic nonhuman primates. Bioorg Med Chem Lett. 2024 Jul 25; 111:129906. PMID: 39059565.
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    3. Damuka N, Irmen RE, Krizan I, Miller M, Gollapelli KK, Bhoopal B, Deep O, Bansode A, Lockhart SN, Orr ME, Jadiya P, Bashetti N, Kumar JVS, Mintz A, Whitlow CT, Craft S, Macauley SL, Solingapuram Sai KK. Exploring microtubule dynamics in Alzheimer's disease: Longitudinal assessment using [11C]MPC-6827 PET imaging in rodent models of Alzheimer's-related pathology. Alzheimers Dement. 2024 Jul 05. PMID: 38967283.
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    4. Rudolph MD, Sutphen CL, Register TC, Whitlow CT, Solingapuram Sai KK, Hughes TM, Bateman JR, Dage JL, Russ KA, Mielke MM, Craft S, Lockhart SN. Associations among plasma, MRI, and amyloid PET biomarkers of Alzheimer's disease and related dementias and the impact of health-related comorbidities in a community-dwelling cohort. Alzheimers Dement. 2024 May 15. PMID: 38747525.
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    5. Deycmar S, Johnson BJ, Ray K, Schaaf GW, Ryan DP, Cullin C, Dozier BL, Ferguson B, Bimber BN, Olson JD, Caudell DL, Whitlow CT, Solingapuram Sai KK, Romero EC, Villinger FJ, Burgos AG, Ainsworth HC, Miller LD, Hawkins GA, Chou JW, Gomes B, Hettich M, Ceppi M, Charo J, Cline JM. Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques. J Transl Med. 2024 Mar 19; 22(1):292. PMID: 38504345.
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    6. Myburgh PJ, Solingapuram Sai KK. Two decades of [11C]PiB synthesis, 2003-2023: a review. Am J Nucl Med Mol Imaging. 2024; 14(1):48-62. PMID: 38500746.
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    7. Zuo Y, Solingapuram Sai KK, Jazic A, Bansode AH, Rose JE, Mukhin AG. Comparison of brain nicotine accumulation from traditional combustible cigarettes and electronic cigarettes with different formulations. Neuropsychopharmacology. 2024 Jan 15. PMID: 38225397.
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    8. Solingapuram Sai KK, Erichsen JM, Gollapelli KK, Krizan I, Miller M, Bansode A, Jorgensen MJ, Register T, Cazzola C, Gandhi R, Suman J, Craft S. First Biodistribution Study of [68Ga]Ga-NOTA-Insulin Following Intranasal Administration in Adult Vervet Monkeys. J Alzheimers Dis. 2024; 101(1):309-320. PMID: 39213084.
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    9. Rather HA, Almousa S, Kumar A, Sharma M, Pennington I, Kim S, Su Y, He Y, Ghara AR, Sai KKS, Navone NM, Vander Griend DJ, Deep G. The ß-Secretase 1 Enzyme as a Novel Therapeutic Target for Prostate Cancer. Cancers (Basel). 2023 Dec 19; 16(1). PMID: 38201438.
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    10. Myburgh PJ, Sai KKS. Development and Optimization of 11C-Labeled Radiotracers: A Review of the Modern Quality Control Design Process. ACS Pharmacol Transl Sci. 2023 Nov 10; 6(11):1616-1631. PMID: 37974626.
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    11. Myburgh PJ, Moore MD, Pathirannahel BL, Grace LR, Solingapuram Sai KK. Fully automated production of [11C]PiB for clinical use on Trasis-AllinOne synthesizer module. Appl Radiat Isot. 2023 Sep 28; 202:111040. PMID: 37788544.
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    12. Bhoopal B, Gollapelli KK, Damuka N, Miller M, Krizan I, Bansode A, Register T, Frye BM, Kim J, Mintz A, Orr M, Craft S, Whitlow C, Lockhart SN, Shively C, Solingapuram Sai KK. Preliminary PET Imaging of Microtubule-Based PET Radioligand [11C]MPC-6827 in a Nonhuman Primate Model of Alzheimer's Disease. ACS Chem Neurosci. 2023 Sep 19. PMID: 37724996.
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    13. Jed E Rose, Arkadiusz K. Kuczaj, Alexey G. Mukhin, Julia Hoeng, Kiran Kumar Solingapuram Sai. Deposition of 11C-radiolabeled nicotine-containing aerosol in an airway cast model using positron emission tomography (PET). Aerosol Science and Technology. 2023; 1-12. View Publication.
    14. Allen MI, Duke AN, Nader SH, Adler-Neal A, Solingapuram Sai KK, Reboussin BA, Gage HD, Voll RJ, Mintz A, Goodman MM, Nader MA. PET imaging of dopamine transporters and D2/D3 receptors in female monkeys: effects of chronic cocaine self-administration. Neuropsychopharmacology. 2023 Jun 22. PMID: 37349473.
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    15. Bansode AH, Damuka N, Bashetti N, Gollapelli KK, Krizan I, Bhoopal B, Miller M, Jv SK, Whitlow CT, McClain D, Ma T, Jorgensen MJ, Solingapuram Sai KK. First GPR119 PET Imaging Ligand: Synthesis, Radiochemistry, and Preliminary Evaluations. J Med Chem. 2023 Jun 14. PMID: 37315328.
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    16. Bansode AH, Bhoopal B, Gollapelli KK, Damuka N, Krizan I, Miller M, Craft S, Mintz A, Solingapuram Sai KK. Binding Parameters of [11C]MPC-6827, a Microtubule-Imaging PET Radiopharmaceutical in Rodents. Pharmaceuticals (Basel). 2023 Mar 27; 16(4). PMID: 37111252.
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    17. Solingapuram Sai KK, Rose JE, Mukhin AG. Effect Of Electronic Cigarette Liquid Ph On Retention Of 11c-Nicotine In A Respiratory Tract Model. Nicotine Tob Res. 2023 Mar 11. PMID: 36905343.
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    18. Czoty PW, Tryhus AM, Solingapuram Sai KK, Nader SH, Epperly PM. Association of dopamine D2-like and D3 receptor function with initial sensitivity to cocaine reinforcement in male rhesus monkeys. Brain Res. 2023 Mar 11; 148323. PMID: 36914041.
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    19. Nerella SG, Kumar M, Solingapuram Sai KK, Digwal CS. Editorial: Development of selective carbon-11 radioligands for target-based PET molecular imaging in oncology, cardiology and neurology. Front Med (Lausanne). 2023; 10:1137088. PMID: 36756181.
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    20. Maracaja L, Khanna AK, Murphy SV, Maracaja DLV, Lane MR, Khoury O, Tan J, Damuka N, Crawford FF, Bottoms JA, Miller MD, Kaczka DW, Jordam JE, Sai KKS. Positron Emission Tomography-Computed Tomography Imaging of Selective Lobar Delivery of Stem Cells in Ex Vivo Lung Model of Mechanical Ventilation. J Aerosol Med Pulm Drug Deliv. 2022 Dec 30. PMID: 36594924.
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    21. Damuka N, Bashetti N, Mintz A, Bansode AH, Miller M, Krizan I, Furdui C, Bhoopal B, Gollapelli KK, Shanmukha Kumar JV, Deep G, Dugan G, Cline M, Solingapuram Sai KK. [18F]KS1, a novel ascorbate-based ligand images ROS in tumor models of rodents and nonhuman primates. Biomed Pharmacother. 2022 Dec; 156:113937. PMID: 36411624.
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    22. Lyu Q, Namjoshi SV, McTyre E, Topaloglu U, Barcus R, Chan MD, Cramer CK, Debinski W, Gurcan MN, Lesser GJ, Lin HK, Munden RF, Pasche BC, Sai KKS, Strowd RE, Tatter SB, Watabe K, Zhang W, Wang G, Whitlow CT. A transformer-based deep-learning approach for classifying brain metastases into primary organ sites using clinical whole-brain MRI images. Patterns (N Y). 2022 Nov 11; 3(11):100613. PMID: 36419451.
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    23. Johnson BN, Kumar A, Su Y, Singh S, Sai KKS, Nader SH, Li S, Reboussin BA, Huang Y, Deep G, Nader MA. PET imaging of kappa opioid receptors and receptor expression quantified in neuron-derived extracellular vesicles in socially housed female and male cynomolgus macaques. Neuropsychopharmacology. 2022 Sep 13. PMID: 36100655.
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    24. Say FM, Tryhus AM, Epperly PM, Nader SH, Solingapuram Sai KK, George BE, Kirse HA, Czoty PW. Effects of chronic cocaine and ethanol self-administration on brain dopamine receptors in a rhesus monkey model of polysubstance abuse. Addict Biol. 2022 Sep; 27(5):e13219. PMID: 36001440.
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    25. Zuo Y, Mukhin AG, Berg H, Morgan JD, Mintz A, Rose JE, Solingapuram Sai KK. Comparison of brain nicotine uptake from electronic cigarettes and combustible cigarettes. Neuropsychopharmacology. 2022 Aug 12. PMID: 35962133.
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    26. Damuka N, Orr ME, Bansode AH, Krizan I, Miller M, Lee J, Macauley SL, Whitlow CT, Mintz A, Craft S, Solingapuram Sai KK. Preliminary mechanistic insights of a brain-penetrant microtubule imaging PET ligand in a tau-knockout mouse model. EJNMMI Res. 2022 Jul 26; 12(1):41. PMID: 35881263.
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    27. Frye BM, Craft S, Register TC, Kim J, Whitlow CT, Barcus RA, Lockhart SN, Sai KKS, Shively CA. Early Alzheimer's disease-like reductions in gray matter and cognitive function with aging in nonhuman primates. Alzheimers Dement (N Y). 2022; 8(1):e12284. PMID: 35310523.
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    28. Damuka N, Martin TJ, Bansode AH, Krizan I, Martin CW, Miller M, Whitlow CT, Nader MA, Solingapuram Sai KK. Initial Evaluations of the Microtubule-Based PET Radiotracer, [11C]MPC-6827 in a Rodent Model of Cocaine Abuse. Front Med (Lausanne). 2022; 9:817274. PMID: 35295607.
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    29. Damuka N, Solingapuram Sai KK. Method to Development of PET Radiopharmaceutical for Cancer Imaging. Methods Mol Biol. 2022; 2413:13-22. PMID: 35044650.
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    30. Damuka N, Dodda M, Solingapuram Sai KK. PET Use in Cancer Diagnosis, Treatment, and Prognosis. Methods Mol Biol. 2022; 2413:23-35. PMID: 35044651.
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    31. Solingapuram Sai KK, Chen X, Li Z, Zhu C, Shukla K, Forshaw TE, Wu H, Vance SA, Pathirannahel BL, Madonna M, Dewhirst MW, Tsang AW, Poole LB, Ramanujam N, King SB, Furdui CM. [18F]Fluoro-DCP, a first generation PET radiotracer for monitoring protein sulfenylation in vivo. Redox Biol. 2021 Dec 18; 49:102218. PMID: 34952463.
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    32. Lockhart SN, Schaich CL, Craft S, Sachs BC, Rapp SR, Jung Y, Whitlow CT, Solingapuram Sai KK, Cleveland M, Williams BJ, Burke GL, Bertoni A, Hayden KM, Hughes TM. Associations among vascular risk factors, neuroimaging biomarkers, and cognition: Preliminary analyses from the Multi-Ethnic Study of Atherosclerosis (MESA). Alzheimers Dement. 2021 Sep 05. PMID: 34482601.
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    33. Chen DL, Agapov E, Wu K, Engle JT, Solingapuram Sai KK, Arentson E, Spayd KJ, Moreland KT, Toth K, Byers DE, Pierce RA, Atkinson JJ, Laforest R, Gelman AE, Holtzman MJ. Selective Imaging of Lung Macrophages Using [11C]PBR28-Based Positron Emission Tomography. Mol Imaging Biol. 2021 Jun 16. PMID: 34137002.
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    34. Damuka N, Orr M, Czoty PW, Weiner JL, Martin TJ, Nader MA, Bansode AH, Liyana Pathirannahel BS, Mintz A, Macauley SL, Craft S, Solingapuram Sai KK. Effect of ethanol and cocaine on [11C]MPC-6827 uptake in SH-SY5Y cells. Mol Biol Rep. 2021 Apr; 48(4):3871-3876. PMID: 33880672.
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    35. Petropoulou PI, Mosialou I, Shikhel S, Hao L, Panitsas K, Bisikirska B, Luo N, Bahna F, Kim J, Carberry P, Zanderigo F, Simpson N, Bakalian M, Kassir S, Shapiro L, Underwood MD, May CM, Soligapuram Sai KK, Jorgensen MJ, Confavreux CB, Shapses S, Laferrère B, Mintz A, Mann JJ, Rubin M, Kousteni S. Lipocalin-2 is an anorexigenic signal in primates. Elife. 2020 11 24; 9. PMID: 33231171.
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    36. Hsiaoju Lee, Naresh Damuka, John A Katzenellenbogen, Bhuddhika Liyana Pathirannahel, Jinbin Xu, Robert H Mach, Kiran Kumar Solingapuram Sai* . Initial Biological Evaluations of [18F]KS-7-51 to Image PPAR-? in Tumor Mice Model. Journal of Radiology & Radiation therapy. 2020; 1(7):1086. View Publication.
    37. Kiran Kumar Solingapuram Sai,*Jaya Prabhakaran,Naresh Damuka, Suzanne Craft, Shamyaa A. Rajagopal, Akiva Mintz, John Mann, and Dileep Kumar. Synthesis and Initial In Vivo Evaluations of [11C]WX-132-18B, a Microtubule PET Imaging Agent. Chemistry Select. 2020; 5:9623-9625. View Publication.
    38. Naresh Damuka, Paul W. Czoty, Ashley T. Davis, Michael A. Nader, Susan H. Nader, Suzanne Craft, Shannon L. Macauley, Lindsey K. Galbo, Phillip M. Epperly, Christopher T. Whitlow, April T. Davenport, Thomas J. Martin, James B. Daunais, Akiva Mintz and Kiran Kumar Solingapuram Sai*. PET Imaging of [11C]MPC-6827, a Microtubule-Based Radiotracer in Non-Human Primate Brains . Molecules . 2020; 2289(25):1-7. View Publication.
    39. J S Dileep Kumar, Jaya Prabhakaran, Naresh Damuka, Justin Wayne Hines, Skylar Norman, Meghana Dodda, J John Mann, Akiva Mintz, Kiran Kumar Solingapuram Sai* . In vivo comparison of N- 11 CH 3 vs O- 11 CH 3 radiolabeled microtubule targeted PET ligands. Bioorg Med Chem Lett. 2020; 2(30):126785. View Publication.
    40. J. S. DILEEP KUMAR, JAYA PRABHAKARAN, NARESH DAMUKA JUSTIN W. HINES, STEVEN J. KRIDEL, J. JOHN MANN, AKIVA MINTZ, KIRAN KUMAR SOLINGAPURAM SAI*. EVALUATION OF [11C]MPC-6827 AS A MICROTUBULE TARGETING PET RADIOTRACER IN CANCER CELL LINES. International Journal of Pharmacy and Pharmaceutical Sciences. 2020; 12(1):43-47. View Publication.
    41. Dileep Kumar JS, Prabhakaran J, Damuka N, Hines JW, Norman S, Dodda M, John Mann J, Mintz A, Sai KKS. In vivo comparison of N-11CH3 vs O-11CH3 radiolabeled microtubule targeted PET ligands. Bioorg Med Chem Lett. 2020 01 15; 30(2):126785. PMID: 31753695.
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    42. Solingapuram Sai KK, Zuo Y, Rose JE, Garg PK, Garg S, Nazih R, Mintz A, Mukhin AG. Rapid Brain Nicotine Uptake from Electronic Cigarettes. J Nucl Med. 2020 06; 61(6):928-930. PMID: 31676729.
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    43. Solingapuram Sai JKK, Hurley RA, Dodda M, Taber KH. Positron Emission Tomography: Updates on Imaging of Addiction. J Neuropsychiatry Clin Neurosci. 2019 Fall; 31(4):A6-288. PMID: 31613195.
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    44. Neth BJ, Mintz A, Whitlow C, Jung Y, Solingapuram Sai K, Register TC, Kellar D, Lockhart SN, Hoscheidt S, Maldjian J, Heslegrave AJ, Blennow K, Cunnane SC, Castellano CA, Zetterberg H, Craft S. Modified ketogenic diet is associated with improved cerebrospinal fluid biomarker profile, cerebral perfusion, and cerebral ketone body uptake in older adults at risk for Alzheimer's disease: a pilot study. Neurobiol Aging. 2020 02; 86:54-63. PMID: 31757576.
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    45. Bashetti N, Shanmukha Kumar JV, Seelam NV, Prasanna B, Mintz A, Damuka N, Devanathan S, Solingapuram Sai KK. One-pot synthesis of novel tert-butyl-4-substituted phenyl-1H-1,2,3-triazolo piperazine/piperidine carboxylates, potential GPR119 agonists. Bioorg Med Chem Lett. 2019 12 01; 29(23):126707. PMID: 31630858.
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    46. Claus C, Ferrara C, Xu W, Sam J, Lang S, Uhlenbrock F, Albrecht R, Herter S, Schlenker R, Hüsser T, Diggelmann S, Challier J, Mössner E, Hosse RJ, Hofer T, Brünker P, Joseph C, Benz J, Ringler P, Stahlberg H, Lauer M, Perro M, Chen S, Küttel C, Bhavani Mohan PL, Nicolini V, Birk MC, Ongaro A, Prince C, Gianotti R, Dugan G, Whitlow CT, Solingapuram Sai KK, Caudell DL, Burgos-Rodriguez AG, Cline JM, Hettich M, Ceppi M, Giusti AM, Crameri F, Driessen W, Morcos PN, Freimoser-Grundschober A, Levitsky V, Amann M, Grau-Richards S, von Hirschheydt T, Tournaviti S, Mølhøj M, Fauti T, Heinzelmann-Schwarz V, Teichgräber V, Colombetti S, Bacac M, Zippelius A, Klein C, Umaña P. Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy. Sci Transl Med. 2019 06 12; 11(496). PMID: 31189721.
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    47. Solingapuram Sai KK, Bashetti N, Chen X, Norman S, Hines JW, Meka O, Kumar JVS, Devanathan S, Deep G, Furdui CM, Mintz A. Initial biological evaluations of 18F-KS1, a novel ascorbate derivative to image oxidative stress in cancer. EJNMMI Res. 2019 May 17; 9(1):43. PMID: 31101996.
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    48. Prabhakaran J, Sai KKS, Sattiraju A, Mintz A, Mann JJ, Kumar JSD. Radiosynthesis and evaluation of [11C]CMP, a high affinity GSK3 ligand. Bioorg Med Chem Lett. 2019 03 15; 29(6):778-781. PMID: 30709652.
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    49. Pandya DN, Bhatt NB, Almaguel F, Rideout-Danner S, Gage HD, Solingapuram Sai KK, Wadas TJ. 89Zr-Chloride Can Be Used for Immuno-PET Radiochemistry Without Loss of Antigen Reactivity In Vivo. J Nucl Med. 2019 05; 60(5):696-701. PMID: 30442753.
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    50. Solingapuram Sai KK, Prabhakaran J, Ramanathan G, Rideout S, Whitlow C, Mintz A, Mann JJ, Kumar JSD. Radiosynthesis and Evaluation of [11C]HD-800, a High Affinity Brain Penetrant PET Tracer for Imaging Microtubules. ACS Med Chem Lett. 2018 May 10; 9(5):452-456. PMID: 29795758.
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    51. Prudner BC, Sun F, Kremer JC, Xu J, Huang C, Sai KKS, Morgan Z, Leeds H, McConathy J, Van Tine BA. Amino Acid Uptake Measured by [18F]AFETP Increases in Response to Arginine Starvation in ASS1-Deficient Sarcomas. Theranostics. 2018; 8(8):2107-2116. PMID: 29721066.
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    52. Kumar JSD, Solingapuram Sai KK, Prabhakaran J, Oufkir HR, Ramanathan G, Whitlow CT, Dileep H, Mintz A, Mann JJ. Radiosynthesis and in Vivo Evaluation of [11C]MPC-6827, the First Brain Penetrant Microtubule PET Ligand. J Med Chem. 2018 03 08; 61(5):2118-2123. PMID: 29457976.
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    53. John WS, Martin TJ, Solingapuram Sai KK, Nader SH, Gage HD, Mintz A, Nader MA. Chronic ?9-THC in Rhesus Monkeys: Effects on Cognitive Performance and Dopamine D2/D3 Receptor Availability. J Pharmacol Exp Ther. 2018 02; 364(2):300-310. PMID: 29203575.
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    54. Solingapuram Sai KK, Donald Gage H, Almaguel F, Neth B, Hughes TM, Tremblay S, Castellano CA, Cunnane SC, Jorgensen MJ, Craft S, Mintz A. Automated synthesis of 1-[11C]acetoacetate on a TRASIS AIO module. Appl Radiat Isot. 2017 Nov; 129:57-61. PMID: 28806598.
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    55. Sattiraju A, Solingapuram Sai KK, Xuan A, Pandya DN, Almaguel FG, Wadas TJ, Herpai DM, Debinski W, Mintz A. IL13RA2 targeted alpha particle therapy against glioblastomas. Oncotarget. 2017 Jun 27; 8(26):42997-43007. PMID: 28562337.
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    56. Sattiraju A, Xiong X, Pandya DN, Wadas TJ, Xuan A, Sun Y, Jung Y, Sai KKS, Dorsey JF, Li KC, Mintz A. Alpha Particle Enhanced Blood Brain/Tumor Barrier Permeabilization in Glioblastomas Using Integrin Alpha-v Beta-3-Targeted Liposomes. . 2017 10; 16(10):2191-2200. PMID: 28619756.
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    57. Prabhakaran J, Zanderigo F, Sai KKS, Rubin-Falcone H, Jorgensen MJ, Kaplan JR, Mintz A, Mann JJ, Kumar JSD. Radiosynthesis and in Vivo Evaluation of [11C]A1070722, a High Affinity GSK-3 PET Tracer in Primate Brain. ACS Chem Neurosci. 2017 08 16; 8(8):1697-1703. PMID: 28485573.
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    58. Sai KKS, Zachar Z, Bingham PM, Mintz A. Metabolic PET Imaging in Oncology. AJR Am J Roentgenol. 2017 Aug; 209(2):270-276. PMID: 28463521.
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    59. Solingapuram Sai KK, Prabhakaran J, Sattiraju A, Mann JJ, Mintz A, Kumar JSD. Radiosynthesis and evaluation of IGF1R PET ligand [11C]GSK1838705A. Bioorg Med Chem Lett. 2017 07 01; 27(13):2895-2897. PMID: 28479199.
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    60. Sai KKS, Sattiraju A, Almaguel FG, Xuan A, Rideout S, Krishnaswamy RS, Zhang J, Herpai DM, Debinski W, Mintz A. Peptide-based PET imaging of the tumor restricted IL13RA2 biomarker. Oncotarget. 2017 Aug 01; 8(31):50997-51007. PMID: 28881623.
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    61. Solingapuram Sai KK, Das BC, Sattiraju A, Almaguel FG, Craft S, Mintz A. Radiolabeling and initial biological evaluation of [18F]KBM-1 for imaging RAR-a receptors in neuroblastoma. Bioorg Med Chem Lett. 2017 03 15; 27(6):1425-1427. PMID: 28216044.
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    62. Sattiraju A, Sai KKS, Mintz A. Glioblastoma Stem Cells and Their Microenvironment. Adv Exp Med Biol. 2017; 1041:119-140. PMID: 29204831.
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    63. Prabhakaran J, Solingapuram Sai KK, Zanderigo F, Rubin-Falcone H, Jorgensen MJ, Kaplan JR, Tooke KI, Mintz A, Mann JJ, Kumar JSD. In vivo evaluation of [18F]FECIMBI-36, an agonist 5-HT2A/2C receptor PET radioligand in nonhuman primate. Bioorg Med Chem Lett. 2017 01 01; 27(1):21-23. PMID: 27889455.
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    64. Birbrair A, Sattiraju A, Zhu D, Zulato G, Batista I, Nguyen VT, Messi ML, Solingapuram Sai KK, Marini FC, Delbono O, Mintz A. Novel Peripherally Derived Neural-Like Stem Cells as Therapeutic Carriers for Treating Glioblastomas. Stem Cells Transl Med. 2017 02; 6(2):471-481. PMID: 28191774.
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    65. Kiran Kumar Solingapuram Sai *, Don Gage , Mike Nader, Robert H. Mach , Akiva Mintz . Improved Automated Radiosynthesis of [11C]PBR28. Sci. Pharm. 2015; (83):413-427.
    66. Solingapuram Sai KK, Gage D, Nader M, Mach RH, Mintz A. Improved Automated Radiosynthesis of [(11)C]PBR28. Sci Pharm. 2015 Jul-Sep; 83(3):413-27. PMID: 26839827.
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    67. Wadas TJ, Pandya DN, Solingapuram Sai KK, Mintz A. Molecular targeted a-particle therapy for oncologic applications. AJR Am J Roentgenol. 2014 Aug; 203(2):253-60. PMID: 25055256.
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    68. Sai KK, Fan J, Tu Z, Zerkel P, Mach RH, Kharasch ED. Automated radiochemical synthesis and biodistribution of [¹¹C]l-a-acetylmethadol ([¹¹C]LAAM). Appl Radiat Isot. 2014 Sep; 91:135-40. PMID: 24935116.
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    69. Sai KK, Huang C, Yuan L, Zhou D, Piwnica-Worms D, Garbow JR, Engelbach JA, Mach RH, Rich KM, McConathy J. 18F-AFETP, 18F-FET, and 18F-FDG imaging of mouse DBT gliomas. J Nucl Med. 2013 Jul; 54(7):1120-6. PMID: 23650628.
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    70. Sai KK, Jones LA, Mach RH. Development of (18)F-labeled PET probes for imaging cell proliferation. Curr Top Med Chem. 2013; 13(8):892-908. PMID: 23590172.
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    71. Solingapuram Sai KK, Kil KE, Tu Z, Chu W, Finck BN, Rothfuss JM, Shoghi KI, Welch MJ, Gropler RJ, Mach RH. Synthesis, radiolabeling and initial in vivo evaluation of [(11)C]KSM-01 for imaging PPAR-a receptors. Bioorg Med Chem Lett. 2012 Oct 01; 22(19):6233-6. PMID: 22939697.
      Citations:    
    72. Sai KK, O'Connor MJ, Klumpp DA. Aza-Nazarov cyclization cascades. Tetrahedron Lett. 2011 Apr 27; 52(17):2195-2198. PMID: 21660198.
      Citations:    
    73. Sai KK, Tokarz MJ, Malunchuk AP, Zheng C, Gilbert TM, Klumpp DA. N-heterocyclic superelectrophiles and evidence for single electron transfer chemistry. J Am Chem Soc. 2008 Nov 05; 130(44):14388-9. PMID: 18841889.
      Citations:    
    74. Sai KK, Esteves PM, da Penha ET, Klumpp DA. Superacid-promoted reactions of alpha-ketoamides and related systems. J Org Chem. 2008 Sep 05; 73(17):6506-12. PMID: 18665649.
      Citations:    
    75. Sai KK, Gilbert TM, Klumpp DA. Knorr cyclizations and distonic superelectrophiles. J Org Chem. 2007 Dec 07; 72(25):9761-4. PMID: 17999519.
      Citations:    
    76. Zhang Y, DeSchepper DJ, Gilbert TM, Sai KK, Klumpp DA. Superacid promoted reactions of N-acyliminium salts and evidence for the involvement of superelectrophiles. Chem Commun (Camb). 2007 Oct 21; (39):4032-4. PMID: 17912406.
      Citations:    
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