Intravenous paclitaxel administration in the rat induces a peripheral sensory neuropathy characterized by macrophage infiltration and injury to sensory neurons and their supporting cells.
Peters CM, Jimenez-Andrade JM, Jonas BM, Sevcik MA, Koewler NJ, Ghilardi JR, Wong GY, Mantyh PW. Intravenous paclitaxel administration in the rat induces a peripheral sensory neuropathy characterized by macrophage infiltration and injury to sensory neurons and their supporting cells. Exp Neurol. 2007 Jan; 203(1):42-54.
-
Activating Transcription Factor 3
-
Animals
-
Antigens, CD
-
Antigens, Differentiation, Myelomonocytic
-
Antineoplastic Agents, Phytogenic
-
Chemotaxis, Leukocyte
-
Disease Models, Animal
-
Ganglia, Spinal
-
Glial Fibrillary Acidic Protein
-
Hyperalgesia
-
Injections, Intravenous
-
Macrophages
-
Male
-
Microglia
-
Neurons, Afferent
-
Paclitaxel
-
Peripheral Nerves
-
Peripheral Nervous System Diseases
-
Posterior Horn Cells
-
Rats
-
Rats, Sprague-Dawley
-
Satellite Cells, Perineuronal
-
Schwann Cells