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Last Name

Sean L. Simpson, Ph.D.

TitleAssociate Professor
InstitutionWake Forest School of Medicine
DepartmentBiostats-Data Science Faculty
Address
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    Collapse Research 
    Collapse research activities and funding
    K25EB012236     (SIMPSON, SEAN L)Sep 1, 2012 - Aug 31, 2017
    NIH/NIBIB
    Statistical Methods for Whole-Brain Connectivety Networks
    Role: Principal Investigator

    R01EB024559     (SIMPSON, SEAN L)Jun 15, 2018 - Feb 28, 2022
    NIH/NIBIB
    Analytical Tools for Complex Brain Networks: Fusing Novel Statistical Methods and Network Science to Understand Brain Function
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Tegeler CL, Shaltout HA, Lee SW, Simpson SL, Gerdes L, Tegeler CH. High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM) improves symptoms and autonomic function for insomnia: A randomized, placebo-controlled clinical trial. Brain Behav. 2020 Sep 17; e01826. PMID: 32940419.
      View in: PubMed
    2. Tegeler CL, Shaltout HA, Lee SW, Simpson SL, Gerdes L, Tegeler CH. Pilot Trial of a Noninvasive Closed-Loop Neurotechnology for Stress-Related Symptoms in Law Enforcement: Improvements in Self-Reported Symptoms and Autonomic Function. Glob Adv Health Med. 2020; 9:2164956120923288. PMID: 32426179.
      View in: PubMed
    3. Garg RK, Khan J, Dawe RJ, Conners J, John S, Prabhakaran S, Kocak M, Bhabad S, Simpson SL, Ouyang B, Jhaveri M, Bleck TP. The Influence of Diffusion Weighted Imaging Lesions on Outcomes in Patients with Acute Spontaneous Intracerebral Hemorrhage. Neurocrit Care. 2020 Feb 18. PMID: 32072457.
      View in: PubMed
    4. Bahrami M, Lyday RG, Casanova R, Burdette JH, Simpson SL, Laurienti PJ. Using Low-Dimensional Manifolds to Map Relationships Between Dynamic Brain Networks. Front Hum Neurosci. 2019; 13:430. PMID: 31920590.
      View in: PubMed
    5. Peterson H, Simpson SL, Laurienti PJ. Wake Forest Alcohol Imagery Set: Development and Validation of a Large Standardized Alcohol Imagery Dataset. Alcohol Clin Exp Res. 2019 12; 43(12):2559-2567. PMID: 31595975.
      View in: PubMed
    6. Bahrami M, Laurienti PJ, Simpson SL. Analysis of brain subnetworks within the context of their whole-brain networks. Hum Brain Mapp. 2019 12 01; 40(17):5123-5141. PMID: 31441167.
      View in: PubMed
    7. Echouffo-Tcheugui JB, Chen H, Kalyani RR, Sims M, Simpson S, Effoe VS, Correa A, Bertoni AG, Golden SH. Glycemic Markers and Subclinical Cardiovascular Disease: The Jackson Heart Study. Circ Cardiovasc Imaging. 2019 03; 12(3):e008641. PMID: 30879330.
      View in: PubMed
    8. Mokhtari F, Akhlaghi MI, Simpson SL, Wu G, Laurienti PJ. Sliding window correlation analysis: Modulating window shape for dynamic brain connectivity in resting state. Neuroimage. 2019 04 01; 189:655-666. PMID: 30721750.
      View in: PubMed
    9. Simpson SL, Bahrami M, Laurienti PJ. A mixed-modeling framework for analyzing multitask whole-brain network data. Netw Neurosci. 2019; 3(2):307-324. PMID: 30793084.
      View in: PubMed
    10. Lee SW, Laurienti PJ, Burdette JH, Tegeler CL, Morgan AR, Simpson SL, Gerdes L, Tegeler CH. Functional Brain Network Changes Following Use of an Allostatic, Closed-Loop, Acoustic Stimulation Neurotechnology for Military-Related Traumatic Stress. J Neuroimaging. 2019 Jan; 29(1):70-78. PMID: 30302866.
      View in: PubMed
    11. Bahrami M, Laurienti PJ, Simpson SL. A MATLAB toolbox for multivariate analysis of brain networks. Hum Brain Mapp. 2019 Jan; 40(1):175-186. PMID: 30256496.
      View in: PubMed
    12. Solo V, Poline JB, Lindquist MA, Simpson SL, Bowman FD, Chung MK, Cassidy B. Connectivity in fMRI: Blind Spots and Breakthroughs. IEEE Trans Med Imaging. 2018 07; 37(7):1537-1550. PMID: 29969406.
      View in: PubMed
    13. Shaltout HA, Lee SW, Tegeler CL, Hirsch JR, Simpson SL, Gerdes L, Tegeler CH. Improvements in Heart Rate Variability, Baroreflex Sensitivity, and Sleep After Use of Closed-Loop Allostatic Neurotechnology by a Heterogeneous Cohort. Front Public Health. 2018; 6:116. PMID: 29922641.
      View in: PubMed
    14. Mokhtari F, Rejeski WJ, Zhu Y, Wu G, Simpson SL, Burdette JH, Laurienti PJ. Dynamic fMRI networks predict success in a behavioral weight loss program among older adults. Neuroimage. 2018 06; 173:421-433. PMID: 29471100.
      View in: PubMed
    15. Tegeler CL, Gerdes L, Shaltout HA, Cook JF, Simpson SL, Lee SW, Tegeler CH. Successful use of closed-loop allostatic neurotechnology for post-traumatic stress symptoms in military personnel: self-reported and autonomic improvements. Mil Med Res. 2017 12 22; 4(1):38. PMID: 29502530.
      View in: PubMed
    16. McCrory MC, Spaeder MC, Gower EW, Nakagawa TA, Simpson SL, Coleman MA, Morris PE. Time of Admission to the PICU and Mortality. Pediatr Crit Care Med. 2017 Oct; 18(10):915-923. PMID: 28737595.
      View in: PubMed
    17. Bahrami M, Laurienti PJ, Quandt SA, Talton J, Pope CN, Summers P, Burdette JH, Chen H, Liu J, Howard TD, Arcury TA, Simpson SL. The impacts of pesticide and nicotine exposures on functional brain networks in Latino immigrant workers. Neurotoxicology. 2017 Sep; 62:138-150. PMID: 28583619.
      View in: PubMed
    18. Tegeler CH, Cook JF, Tegeler CL, Hirsch JR, Shaltout HA, Simpson SL, Fidali BC, Gerdes L, Lee SW. Clinical, hemispheric, and autonomic changes associated with use of closed-loop, allostatic neurotechnology by a case series of individuals with self-reported symptoms of post-traumatic stress. BMC Psychiatry. 2017 04 19; 17(1):141. PMID: 28420362.
      View in: PubMed
    19. 3. Bowman FD, Simpson SL, Drake DF . Handbook of Modern Statistical Methods: Handbook of Neuroimaging Data Analysis. Joint fMRI and DTI Models for Brain Connectivity. 2017; 495-516.
    20. Casanova R, Saldana S, Simpson SL, Lacy ME, Subauste AR, Blackshear C, Wagenknecht L, Bertoni AG. Prediction of Incident Diabetes in the Jackson Heart Study Using High-Dimensional Machine Learning. PLoS One. 2016; 11(10):e0163942. PMID: 27727289.
      View in: PubMed
    21. Tegeler CH, Tegeler CL, Cook JF, Lee SW, Gerdes L, Shaltout HA, Miles CM, Simpson SL. A Preliminary Study of the Effectiveness of an Allostatic, Closed-Loop, Acoustic Stimulation Neurotechnology in the Treatment of Athletes with Persisting Post-concussion Symptoms. Sports Med Open. 2016 Dec; 2(1):39. PMID: 27747793.
      View in: PubMed
    22. Mayhugh RE, Moussa MN, Simpson SL, Lyday RG, Burdette JH, Porrino LJ, Laurienti PJ. Moderate-Heavy Alcohol Consumption Lifestyle in Older Adults Is Associated with Altered Central Executive Network Community Structure during Cognitive Task. PLoS One. 2016; 11(8):e0160214. PMID: 27494180.
      View in: PubMed
    23. Simpson SL, Laurienti PJ. Disentangling Brain Graphs: A Note on the Conflation of Network and Connectivity Analyses. Brain Connect. 2016 Mar; 6(2):95-8. PMID: 26414952.
      View in: PubMed
    24. Ip EH, Zhang Q, Sowinski T, Simpson SL. Analysis of Feedback Mechanisms with Unknown Delay Using Sparse Multivariate Autoregressive Method. PLoS One. 2015; 10(8):e0131371. PMID: 26252637.
      View in: PubMed
    25. Simpson S, Burdette J, Laurienti P. The brain science interface. Signif (Oxf). 2015 Aug; 12(4):34-39. PMID: 27441037.
      View in: PubMed
    26. Telesford QK, Simpson SL, Kolaczyk ED. Editorial: Complexity and emergence in brain network analyses. Front Comput Neurosci. 2015; 9:65. PMID: 26082712.
      View in: PubMed
    27. Paolini BM, Laurienti PJ, Simpson SL, Burdette JH, Lyday RG, Rejeski WJ. Global integration of the hot-state brain network of appetite predicts short term weight loss in older adult. Front Aging Neurosci. 2015; 7:70. PMID: 25999855.
      View in: PubMed
    28. Stanley ML, Simpson SL, Dagenbach D, Lyday RG, Burdette JH, Laurienti PJ. Changes in brain network efficiency and working memory performance in aging. PLoS One. 2015; 10(4):e0123950. PMID: 25875001.
      View in: PubMed
    29. Simpson SL, Laurienti PJ. A two-part mixed-effects modeling framework for analyzing whole-brain network data. Neuroimage. 2015 Jun; 113:310-9. PMID: 25796135.
      View in: PubMed
    30. Moussa MN, Simpson SL, Mayhugh RE, Grata ME, Burdette JH, Porrino LJ, Laurienti PJ. Long-term moderate alcohol consumption does not exacerbate age-related cognitive decline in healthy, community-dwelling older adults. Front Aging Neurosci. 2014; 6:341. PMID: 25601835.
      View in: PubMed
    31. McCrory MC, Gower EW, Simpson SL, Nakagawa TA, Mou SS, Morris PE. Off-hours admission to pediatric intensive care and mortality. Pediatrics. 2014 Nov; 134(5):e1345-53. PMID: 25287463.
      View in: PubMed
    32. Fetterhoff D, Opris I, Simpson SL, Deadwyler SA, Hampson RE, Kraft RA. Multifractal analysis of information processing in hippocampal neural ensembles during working memory under ??-tetrahydrocannabinol administration. J Neurosci Methods. 2015 Apr 15; 244:136-53. PMID: 25086297.
      View in: PubMed
    33. Edwards LJ, Simpson SL. An analysis of 24-h ambulatory blood pressure monitoring data using orthonormal polynomials in the linear mixed model. Blood Press Monit. 2014 Jun; 19(3):153-63. PMID: 24667908.
      View in: PubMed
    34. Simpson SL, Edwards LJ, Styner MA, Muller KE. Kronecker product linear exponent AR(1) correlation structures for multivariate repeated measures. PLoS One. 2014; 9(2):e88864. PMID: 24586419.
      View in: PubMed
    35. Simpson SL, Edwards LJ, Styner MA, Muller KE. Separability tests for high-dimensional, low sample size multivariate repeated measures data. J Appl Stat. 2014; 41(11):2450-2461. PMID: 25342869.
      View in: PubMed
    36. Vaughan L, Leng I, Dagenbach D, Resnick SM, Rapp SR, Jennings JM, Brunner RL, Simpson SL, Beavers DP, Coker LH, Gaussoin SA, Sink KM, Espeland MA. Intraindividual variability in domain-specific cognition and risk of mild cognitive impairment and dementia. Curr Gerontol Geriatr Res. 2013; 2013:495793. PMID: 24454359.
      View in: PubMed
    37. Simpson SL, Lyday RG, Hayasaka S, Marsh AP, Laurienti PJ. A permutation testing framework to compare groups of brain networks. Front Comput Neurosci. 2013; 7:171. PMID: 24324431.
      View in: PubMed
    38. Bruce MA, Beech BM, Crook ED, Sims M, Griffith DM, Simpson SL, Ard J, Norris KC. Sex, weight status, and chronic kidney disease among African Americans: the Jackson Heart Study. J Investig Med. 2013 Apr; 61(4):701-7. PMID: 23524947.
      View in: PubMed
    39. Simpson SL, Bowman FD, Laurienti PJ. Analyzing complex functional brain networks: Fusing statistics and network science to understand the brain*† Stat Surv. 2013; 7:1-36. PMID: 25309643.
      View in: PubMed
    40. Simpson SL, Moussa MN, Laurienti PJ. An exponential random graph modeling approach to creating group-based representative whole-brain connectivity networks. Neuroimage. 2012 Apr 02; 60(2):1117-26. PMID: 22281670.
      View in: PubMed
    41. Simpson SL, Hayasaka S, Laurienti PJ. Exponential random graph modeling for complex brain networks. PLoS One. 2011; 6(5):e20039. PMID: 21647450.
      View in: PubMed
    42. Webb BC, Simpson SL, Hairston KG. From politics to parity: using a health disparities index to guide legislative efforts for health equity. Am J Public Health. 2011 Mar; 101(3):554-60. PMID: 21233445.
      View in: PubMed
    43. Simpson SL, Edwards LJ. A circular LEAR correlation structure for cyclical longitudinal data. Stat Methods Med Res. 2013 Jun; 22(3):296-306. PMID: 21216801.
      View in: PubMed
    44. Telesford QK, Simpson SL, Burdette JH, Hayasaka S, Laurienti PJ. The brain as a complex system: using network science as a tool for understanding the brain. Brain Connect. 2011; 1(4):295-308. PMID: 22432419.
      View in: PubMed
    45. Telesford QK, Morgan AR, Hayasaka S, Simpson SL, Barret W, Kraft RA, Mozolic JL, Laurienti PJ. Reproducibility of graph metrics in FMRI networks. Front Neuroinform. 2010; 4:117. PMID: 21165174.
      View in: PubMed
    46. Simpson, Sean L. An adjusted likelihood ratio test for separability in unbalanced multivariate repeated measures data. Statistical Methodology. 2010; 7(5):511-519.
    47. Simpson SL, Edwards LJ, Muller KE, Sen PK, Styner MA. A linear exponent AR(1) family of correlation structures. Stat Med. 2010 Jul 30; 29(17):1825-38. PMID: 20658550.
      View in: PubMed
    48. Slager RE, Simpson SL, Levan TD, Poole JA, Sandler DP, Hoppin JA. Rhinitis associated with pesticide use among private pesticide applicators in the agricultural health study. J Toxicol Environ Health A. 2010; 73(20):1382-93. PMID: 20818537.
      View in: PubMed
    49. Johnson JL, Muller KE, Slaughter JC, Gurka MJ, Gribbin MJ, Simpson SL. POWERLIB: SAS/IML Software for Computing Power in Multivariate Linear Models. J Stat Softw. 2009 Apr 01; 30(5). PMID: 25400516.
      View in: PubMed
    50. Thomas KB, Simpson SL, Tarver WL, Gwede CK. Is social support from family associated with PSA testing? An exploratory analysis using the Health Information National Trends Survey (HINTS) 2005. Am J Mens Health. 2010 Mar; 4(1):50-9. PMID: 19477731.
      View in: PubMed
    51. Muller KE, Edwards LJ, Simpson SL, Taylor DJ. Statistical tests with accurate size and power for balanced linear mixed models. Stat Med. 2007 Aug 30; 26(19):3639-60. PMID: 17394132.
      View in: PubMed
    52. Lark RK, Williams CL, Stadler D, Simpson SL, Henderson RC, Samson-Fang L, Worley G. Serum prealbumin and albumin concentrations do not reflect nutritional state in children with cerebral palsy. J Pediatr. 2005 Nov; 147(5):695-7. PMID: 16291366.
      View in: PubMed
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