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Nancy D. Kock DVM, PhD

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentPathology, Comparative Medicine
Address
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Thakur P, DeBo R, Dugan GO, Bourland JD, Michalson KT, Olson JD, Register TC, Kock ND, Cline JM. Clinicopathologic and Transcriptomic Analysis of Radiation-Induced Lung Injury in Nonhuman Primates. Int J Radiat Oncol Biol Phys. 2021 Apr 20. PMID: 33848608.
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    2. Saenkham P, Jennings-Gee J, Hanson B, Kock ND, Adams LG, Subashchandrabose S. Hyperglucosuria induced by dapagliflozin augments bacterial colonization in the murine urinary tract. Diabetes Obes Metab. 2020 09; 22(9):1548-1555. PMID: 32314507.
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    3. Dadhich P, Bohl JL, Tamburrini R, Zakhem E, Scott C, Kock N, Mitchell E, Gilliam J, Bitar KN. BioSphincters to treat Fecal Incontinence in Nonhuman Primates. Sci Rep. 2019 12 02; 9(1):18096. PMID: 31792260.
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    4. Pen OV, Antinozzi PA, Kock ND, Robinson MB, Willey JS, Bourland JD. Automated, quantitative assessment of epidermal necrosis expression resulting from skin exposure to beta radiation. Biomed Phys Eng Express. 2019 11 25; 6(1):015007. PMID: 33438595.
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    5. Murphy SV, Skardal A, Nelson RA, Sunnon K, Reid T, Clouse C, Kock ND, Jackson J, Soker S, Atala A. Amnion membrane hydrogel and amnion membrane powder accelerate wound healing in a full thickness porcine skin wound model. Stem Cells Transl Med. 2020 01; 9(1):80-92. PMID: 31328435.
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    6. Tafreshi NK, Tichacek CJ, Pandya DN, Doligalski ML, Budzevich MM, Kil H, Bhatt NB, Kock ND, Messina JL, Ruiz EE, Delva NC, Weaver A, Gibbons WR, Boulware DC, Khushalani NI, El-Haddad G, Triozzi PL, Moros EG, McLaughlin ML, Wadas TJ, Morse DL. Melanocortin 1 Receptor-Targeted a-Particle Therapy for Metastatic Uveal Melanoma. J Nucl Med. 2019 08; 60(8):1124-1133. PMID: 30733316.
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    7. Graham-Gurysh E, Kelkar S, McCabe-Lankford E, Kuthirummal N, Brown T, Kock ND, Mohs AM, Levi-Polyachenko N. Hybrid Donor-Acceptor Polymer Particles with Amplified Energy Transfer for Detection and On-Demand Treatment of Breast Cancer. ACS Appl Mater Interfaces. 2018 Mar 07; 10(9):7697-7703. PMID: 29457709.
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    8. Atkins HM, Caudell DL, Hutchison AR, LeGrande AC, Kock ND. Abdominal Wall Endometriosis in a Rhesus Macaque (Macaca mulatta). Comp Med. 2017 Jun 01; 67(3):277-280. PMID: 28662757.
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    9. Hyre AN, Kavanagh K, Kock ND, Donati GL, Subashchandrabose S. Copper Is a Host Effector Mobilized to Urine during Urinary Tract Infection To Impair Bacterial Colonization. Infect Immun. 2017 03; 85(3). PMID: 28031261.
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    10. Kiguchi N, Ding H, Peters CM, Kock ND, Kishioka S, Cline JM, Wagner JD, Ko MC. Altered expression of glial markers, chemokines, and opioid receptors in the spinal cord of type 2 diabetic monkeys. Biochim Biophys Acta Mol Basis Dis. 2017 01; 1863(1):274-283. PMID: 27751964.
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    11. Holbrook BC, Kim JR, Blevins LK, Jorgensen MJ, Kock ND, D'Agostino RB, Aycock ST, Hadimani MB, King SB, Parks GD, Alexander-Miller MA. A Novel R848-Conjugated Inactivated Influenza Virus Vaccine Is Efficacious and Safe in a Neonate Nonhuman Primate Model. J Immunol. 2016 07 15; 197(2):555-64. PMID: 27279374.
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    12. Pandya DN, Hantgan R, Budzevich MM, Kock ND, Morse DL, Batista I, Mintz A, Li KC, Wadas TJ. Preliminary Therapy Evaluation of (225)Ac-DOTA-c(RGDyK) Demonstrates that Cerenkov Radiation Derived from (225)Ac Daughter Decay Can Be Detected by Optical Imaging for In Vivo Tumor Visualization. Theranostics. 2016; 6(5):698-709. PMID: 27022417.
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    13. Kim JR, Holbrook BC, Hayward SL, Blevins LK, Jorgensen MJ, Kock ND, De Paris K, D'Agostino RB, Aycock ST, Mizel SB, Parks GD, Alexander-Miller MA. Inclusion of Flagellin during Vaccination against Influenza Enhances Recall Responses in Nonhuman Primate Neonates. J Virol. 2015 Jul; 89(14):7291-303. PMID: 25948746.
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    14. Holbrook BC, Hayward SL, Blevins LK, Kock N, Aycock T, Parks GD, Alexander-Miller MA. Nonhuman primate infants have an impaired respiratory but not systemic IgG antibody response following influenza virus infection. Virology. 2015 Feb; 476:124-133. PMID: 25543963.
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    15. Suburu J, Shi L, Wu J, Wang S, Samuel M, Thomas MJ, Kock ND, Yang G, Kridel S, Chen YQ. Fatty acid synthase is required for mammary gland development and milk production during lactation. Am J Physiol Endocrinol Metab. 2014 May 15; 306(10):E1132-43. PMID: 24668799.
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    16. Ganguly T, Johnson JB, Kock ND, Parks GD, Deora R. The Bordetella pertussis Bps polysaccharide enhances lung colonization by conferring protection from complement-mediated killing. Cell Microbiol. 2014 Jul; 16(7):1105-18. PMID: 24438122.
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    17. Eckman DM, Stacey RB, Rowe R, D'Agostino R, Kock ND, Sane DC, Torti FM, Yeboah J, Workman S, Lane KS, Hundley WG. Weekly doxorubicin increases coronary arteriolar wall and adventitial thickness. PLoS One. 2013; 8(2):e57554. PMID: 23437398.
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    18. McDaniel AL, Alger HM, Sawyer JK, Kelley KL, Kock ND, Brown JM, Temel RE, Rudel LL. Phytosterol feeding causes toxicity in ABCG5/G8 knockout mice. Am J Pathol. 2013 Apr; 182(4):1131-8. PMID: 23380580.
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    19. Miller MS, Moore JE, Walb MC, Kock ND, Attia A, Isom S, McBride JE, Munley MT. Chemoprevention by N-acetylcysteine of low-dose CT-induced murine lung tumorigenesis. Carcinogenesis. 2013 Feb; 34(2):319-24. PMID: 23104176.
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    20. Pang B, Hong W, Kock ND, Swords WE. Dps promotes survival of nontypeable Haemophilus influenzae in biofilm communities in vitro and resistance to clearance in vivo. Front Cell Infect Microbiol. 2012; 2:58. PMID: 22919649.
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    21. Lan T, Rao A, Haywood J, Kock ND, Dawson PA. Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism. J Hepatol. 2012 Aug; 57(2):359-65. PMID: 22542490.
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    22. Munley MT, Moore JE, Walb MC, Isom SP, Olson JD, Zora JG, Kock ND, Wheeler KT, Miller MS. Cancer-prone mice expressing the Ki-rasG12C gene show increased lung carcinogenesis after CT screening exposures. Radiat Res. 2011 Dec; 176(6):842-8. PMID: 21962004.
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    23. Clark KM, Johnson JB, Kock ND, Mizel SB, Parks GD. Parainfluenza virus 5-based vaccine vectors expressing vaccinia virus (VACV) antigens provide long-term protection in mice from lethal intranasal VACV challenge. Virology. 2011 Oct 25; 419(2):97-106. PMID: 21885079.
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    24. Burke AR, Singh RN, Carroll DL, Owen JD, Kock ND, D'Agostino R, Torti FM, Torti SV. Determinants of the thrombogenic potential of multiwalled carbon nanotubes. Biomaterials. 2011 Sep; 32(26):5970-8. PMID: 21663954.
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    25. Byrd MS, Pang B, Hong W, Waligora EA, Juneau RA, Armbruster CE, Weimer KE, Murrah K, Mann EE, Lu H, Sprinkle A, Parsek MR, Kock ND, Wozniak DJ, Swords WE. Direct evaluation of Pseudomonas aeruginosa biofilm mediators in a chronic infection model. Infect Immun. 2011 Aug; 79(8):3087-95. PMID: 21646454.
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    26. Arnold AC, Shaltout HA, Gilliam-Davis S, Kock ND, Diz DI. Autonomic control of the heart is altered in Sprague-Dawley rats with spontaneous hydronephrosis. . 2011 Jun; 300(6):H2206-13. PMID: 21460193.
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    27. Appt SE, Clarkson TB, Hoyer PB, Kock ND, Goode AK, May MC, Persyn JT, Vail NK, Ethun KF, Chen H, Sen N, Kaplan JR. Experimental induction of reduced ovarian reserve in a nonhuman primate model (Macaca fascicularis). Comp Med. 2010 Oct; 60(5):380-8. PMID: 21262124.
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    28. Yang Q, Kock ND. Effects of dietary fish oil on intestinal adaptation in 20-day-old weanling rats after massive ileocecal resection. Pediatr Res. 2010 Sep; 68(3):183-7. PMID: 20531250.
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    29. Lightfoot JC, D'Agostino RB, Hamilton CA, Jordan J, Torti FM, Kock ND, Jordan J, Workman S, Hundley WG. Novel approach to early detection of doxorubicin cardiotoxicity by gadolinium-enhanced cardiovascular magnetic resonance imaging in an experimental model. Circ Cardiovasc Imaging. 2010 Sep; 3(5):550-8. PMID: 20622140.
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    30. Neal RE, Singh R, Hatcher HC, Kock ND, Torti SV, Davalos RV. Treatment of breast cancer through the application of irreversible electroporation using a novel minimally invasive single needle electrode. Breast Cancer Res Treat. 2010 Aug; 123(1):295-301. PMID: 20191380.
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    31. Sukumar N, Sloan GP, Conover MS, Love CF, Mattoo S, Kock ND, Deora R. Cross-species protection mediated by a Bordetella bronchiseptica strain lacking antigenic homologs present in acellular pertussis vaccines. Infect Immun. 2010 May; 78(5):2008-16. PMID: 20176797.
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    32. Yang Q, Kock ND. Intestinal adaptation following massive ileocecal resection in 20-day-old weanling rats. J Pediatr Gastroenterol Nutr. 2010 Jan; 50(1):16-21. PMID: 19949347.
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    33. Burke A, Ding X, Singh R, Kraft RA, Levi-Polyachenko N, Rylander MN, Szot C, Buchanan C, Whitney J, Fisher J, Hatcher HC, D'Agostino R, Kock ND, Ajayan PM, Carroll DL, Akman S, Torti FM, Torti SV. Long-term survival following a single treatment of kidney tumors with multiwalled carbon nanotubes and near-infrared radiation. Proc Natl Acad Sci U S A. 2009 Aug 04; 106(31):12897-902. PMID: 19620717.
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    34. Armbruster CE, Hong W, Pang B, Dew KE, Juneau RA, Byrd MS, Love CF, Kock ND, Swords WE. LuxS promotes biofilm maturation and persistence of nontypeable haemophilus influenzae in vivo via modulation of lipooligosaccharides on the bacterial surface. Infect Immun. 2009 Sep; 77(9):4081-91. PMID: 19564381.
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    35. Dance-Barnes ST, Kock ND, Moore JE, Lin EY, Mosley LJ, D'Agostino RB, McCoy TP, Townsend AJ, Miller MS. Lung tumor promotion by curcumin. Carcinogenesis. 2009 Jun; 30(6):1016-23. PMID: 19359593.
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    36. Weimer ET, Lu H, Kock ND, Wozniak DJ, Mizel SB. A fusion protein vaccine containing OprF epitope 8, OprI, and type A and B flagellins promotes enhanced clearance of nonmucoid Pseudomonas aeruginosa. Infect Immun. 2009 Jun; 77(6):2356-66. PMID: 19349426.
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    37. Muhammad FS, Goode AK, Kock ND, Arifin EA, Cline JM, Adams MR, Hoyer PB, Christian PJ, Isom S, Kaplan JR, Appt SE. Effects of 4-vinylcyclohexene diepoxide on peripubertal and adult Sprague-Dawley rats: ovarian, clinical, and pathologic outcomes. Comp Med. 2009 Feb; 59(1):46-59. PMID: 19295054.
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    38. Sukumar N, Love CF, Conover MS, Kock ND, Dubey P, Deora R. Active and passive immunizations with Bordetella colonization factor A protect mice against respiratory challenge with Bordetella bronchiseptica. Infect Immun. 2009 Feb; 77(2):885-95. PMID: 19064638.
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    39. Scott LM, Xu X, Veenstra TD, Tooze JA, Wood CE, Register TC, Kock ND, Cline JM. Past oral contraceptive use and current dietary soy isoflavones influence estrogen metabolism in postmenopausal monkeys (Macaca fascicularis). Cancer Epidemiol Biomarkers Prev. 2008 Oct; 17(10):2594-602. PMID: 18843000.
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    40. Jiao Y, Wilkinson J, Di X, Wang W, Hatcher H, Kock ND, D'Agostino R, Knovich MA, Torti FM, Torti SV. Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator. Blood. 2009 Jan 08; 113(2):462-9. PMID: 18815282.
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    41. Pang B, Hong W, West-Barnette SL, Kock ND, Swords WE. Diminished ICAM-1 expression and impaired pulmonary clearance of nontypeable Haemophilus influenzae in a mouse model of chronic obstructive pulmonary disease/emphysema. Infect Immun. 2008 Nov; 76(11):4959-67. PMID: 18794286.
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    42. Ahmed M, Marino TR, Puckett S, Kock ND, Lyles DS. Immune response in the absence of neurovirulence in mice infected with m protein mutant vesicular stomatitis virus. J Virol. 2008 Sep; 82(18):9273-7. PMID: 18614644.
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    43. Sikoski P, Trybus J, Cline JM, Muhammad FS, Eckhoff A, Tan J, Lockard M, Jolley T, Britt S, Kock ND. Cystic mammary adenocarcinoma associated with a prolactin-secreting pituitary adenoma in a New Zealand white rabbit (Oryctolagus cuniculus). Comp Med. 2008 Jun; 58(3):297-300. PMID: 18589874.
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    44. Capraro GA, Johnson JB, Kock ND, Parks GD. Virus growth and antibody responses following respiratory tract infection of ferrets and mice with WT and P/V mutants of the paramyxovirus Simian Virus 5. Virology. 2008 Jul 05; 376(2):416-28. PMID: 18456301.
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    45. Dance-Barnes ST, Kock ND, Floyd HS, Moore JE, Mosley LJ, D'Agostino RB, Pettenati MJ, Miller MS. Effects of mutant human Ki-ras(G12C) gene dosage on murine lung tumorigenesis and signaling to its downstream effectors. Toxicol Appl Pharmacol. 2008 Aug 15; 231(1):77-84. PMID: 18565564.
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    46. Pang B, Winn D, Johnson R, Hong W, West-Barnette S, Kock N, Swords WE. Lipooligosaccharides containing phosphorylcholine delay pulmonary clearance of nontypeable Haemophilus influenzae. Infect Immun. 2008 May; 76(5):2037-43. PMID: 18347044.
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    47. Bates JT, Honko AN, Graff AH, Kock ND, Mizel SB. Mucosal adjuvant activity of flagellin in aged mice. Mech Ageing Dev. 2008 May; 129(5):271-81. PMID: 18367233.
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    48. Lally BE, Geiger GA, Kridel S, Arcury-Quandt AE, Robbins ME, Kock ND, Wheeler K, Peddi P, Georgakilas A, Kao GD, Koumenis C. Identification and biological evaluation of a novel and potent small molecule radiation sensitizer via an unbiased screen of a chemical library. Cancer Res. 2007 Sep 15; 67(18):8791-9. PMID: 17875720.
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    49. Jennings-Gee JE, Moore JE, Xu M, Dance ST, Kock ND, McCoy TP, Carr JJ, Miller MS. Strain-specific induction of murine lung tumors following in utero exposure to 3-methylcholanthrene. Mol Carcinog. 2006 Sep; 45(9):676-84. PMID: 16652375.
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    50. Floyd HS, Jennings-Gee JE, Kock ND, Miller MS. Genetic and epigenetic alterations in lung tumors from bitransgenic Ki-rasG12C expressing mice. Mol Carcinog. 2006 Jul; 45(7):506-17. PMID: 16482519.
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    51. Wilkinson J, Di X, Schönig K, Buss JL, Kock ND, Cline JM, Saunders TL, Bujard H, Torti SV, Torti FM. Tissue-specific expression of ferritin H regulates cellular iron homoeostasis in vivo. Biochem J. 2006 May 01; 395(3):501-7. PMID: 16448386.
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    52. Floyd HS, Farnsworth CL, Kock ND, Mizesko MC, Little JL, Dance ST, Everitt J, Tichelaar J, Whitsett JA, Miller MS. Conditional expression of the mutant Ki-rasG12C allele results in formation of benign lung adenomas: development of a novel mouse lung tumor model. Carcinogenesis. 2005 Dec; 26(12):2196-206. PMID: 16051643.
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    53. Wood CE, Register TC, Anthony MS, Kock ND, Cline JM. Breast and uterine effects of soy isoflavones and conjugated equine estrogens in postmenopausal female monkeys. J Clin Endocrinol Metab. 2004 Jul; 89(7):3462-8. PMID: 15240632.
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    54. Couillard N, Wallace J, Young R, Kock N. Cecal volvulus in two African green monkeys (Cercopithecus athiops sabeus). Comp Med. 2004 Jun; 54(3):324-6. PMID: 15253280.
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