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Last Name

Marlena Moors Westcott, Ph.D.

TitleAssistant Professor
InstitutionWake Forest School of Medicine
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    R03AI153841     (WESTCOTT, MARLENA MOORS)Jun 1, 2020 - May 31, 2021
    Preclinical evaluation of psoralen inactivation as a platform for developing a killed, whole cell vaccine for Enterotoxigenic E. coli (ETEC)
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Westcott MM, Smedberg J, Jorgensen MJ, Puckett S, Lyles DS. Immunogenicity in African Green Monkeys of M Protein Mutant Vesicular Stomatitis Virus Vectors and Contribution of Vector-Encoded Flagellin. Vaccines (Basel). 2018 Mar 19; 6(1). PMID: 29562688.
      View in: PubMed
    2. Westcott MM, Clemens EA, Holbrook BC, King SB, Alexander-Miller MA. The choice of linker for conjugating R848 to inactivated influenza virus determines the stimulatory capacity for innate immune cells. Vaccine. 2018 02 21; 36(9):1174-1182. PMID: 29398273.
      View in: PubMed
    3. Westcott MM, Liu J, Rajani K, D'Agostino R, Lyles DS, Porosnicu M. Interferon Beta and Interferon Alpha 2a Differentially Protect Head and Neck Cancer Cells from Vesicular Stomatitis Virus-Induced Oncolysis. J Virol. 2015 Aug; 89(15):7944-54. PMID: 25995245.
      View in: PubMed
    4. Smedberg JR, Westcott MM, Ahmed M, Lyles DS. Signaling pathways in murine dendritic cells that regulate the response to vesicular stomatitis virus vectors that express flagellin. J Virol. 2014 Jan; 88(2):777-85. PMID: 24198430.
      View in: PubMed
    5. Westcott MM, Ahmed M, Smedberg JR, Rajani KR, Hiltbold EM, Lyles DS. Preservation of dendritic cell function during vesicular stomatitis virus infection reflects both intrinsic and acquired mechanisms of resistance to suppression of host gene expression by viral M protein. J Virol. 2013 Nov; 87(21):11730-40. PMID: 23986580.
      View in: PubMed
    6. Zhu X, Westcott MM, Bi X, Liu M, Gowdy KM, Seo J, Cao Q, Gebre AK, Fessler MB, Hiltbold EM, Hitbold EM, Parks JS. Myeloid cell-specific ABCA1 deletion protects mice from bacterial infection. Circ Res. 2012 Nov 09; 111(11):1398-409. PMID: 22955730.
      View in: PubMed
    7. Henry CJ, Grayson JM, Brzoza-Lewis KL, Mitchell LM, Westcott MM, Cook AS, Hiltbold EM. The roles of IL-12 and IL-23 in CD8+ T cell-mediated immunity against Listeria monocytogenes: Insights from a DC vaccination model. Cell Immunol. 2010; 264(1):23-31. PMID: 20483409.
      View in: PubMed
    8. Westcott MM, Henry CJ, Amis JE, Hiltbold EM. Dendritic cells inhibit the progression of Listeria monocytogenes intracellular infection by retaining bacteria in major histocompatibility complex class II-rich phagosomes and by limiting cytosolic growth. Infect Immun. 2010 Jul; 78(7):2956-65. PMID: 20404078.
      View in: PubMed
    9. Westcott MM, Henry CJ, Cook AS, Grant KW, Hiltbold EM. Differential susceptibility of bone marrow-derived dendritic cells and macrophages to productive infection with Listeria monocytogenes. Cell Microbiol. 2007 Jun; 9(6):1397-411. PMID: 17250592.
      View in: PubMed
    10. Westcott MM, Abi-Habib RJ, Cohen KA, Willingham MC, Liu S, Bugge TH, Leppla SH, Frankel AE. Diphtheria toxin-murine granulocyte-macrophage colony-stimulating factor-induced hepatotoxicity is mediated by Kupffer cells. . 2004 Dec; 3(12):1681-9. PMID: 15634662.
      View in: PubMed
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