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Last Name

Fei Xing, Ph.D.

TitleAssistant Professor
InstitutionWake Forest School of Medicine
DepartmentCancer Biology
Address
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    Collapse Biography 
    Collapse education and training
    Shandong UniversityB.S06/2007biotechnology
    Southern Illinois UniversityPh.D.05/2012molecular oncology

    Collapse Research 
    Collapse research activities and funding
    5R37CA230451-02     (fei xing)Aug 1, 2018 - Jul 30, 2023
    NCI
    Roles of neutrophils in c-Met mediated breast cancer brain metastases
    Role: PI

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Sharma S, Wu SY, Jimenez H, Xing F, Zhu D, Liu Y, Wu K, Tyagi A, Zhao D, Lo HW, Metheny-Barlow L, Sun P, Bourland JD, Chan MD, Thomas A, Barbault A, D'Agostino RB, Whitlow CT, Kirchner V, Blackman C, Pasche B, Watabe K. Ca2+ and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF. EBioMedicine. 2019 Jun; 44:194-208. PMID: 31129098.
      View in: PubMed
    2. Dohm A, Su J, McTyre ER, Taylor JM, Miller LD, Petty WJ, Xing F, Lo HW, Metheny-Barlow LJ, O'Neill S, Bellinger C, Dotson T, Pasche B, Watabe K, Chan MD, Ruiz J. Identification of CD37, cystatin A, and IL-23A gene expression in association with brain metastasis: analysis of a prospective trial. Int J Biol Markers. 2019 Mar; 34(1):90-97. PMID: 30854931.
      View in: PubMed
    3. Liu Y, Pandey PR, Sharma S, Xing F, Wu K, Chittiboyina A, Wu SY, Tyagi A, Watabe K. ID2 and GJB2 promote early-stage breast cancer progression by regulating cancer stemness. Breast Cancer Res Treat. 2019 May; 175(1):77-90. PMID: 30725231.
      View in: PubMed
    4. Shenker RF, McTyre ER, Taksler GB, D'Agostino RB, Cramer CK, Ruiz J, Alphonse-Sullivan NK, Farris M, Watabe K, Xing F, Laxton AW, Tatter SB, Chan MD. Analysis of the drivers of cost of management when patients with brain metastases are treated with upfront radiosurgery. Clin Neurol Neurosurg. 2019 Jan; 176:10-14. PMID: 30468997.
      View in: PubMed
    5. Dohm AE, Hughes R, Wheless W, Lecompte M, Lanier C, Ruiz J, Watabe K, Xing F, Su J, Cramer C, Laxton A, Tatter S, Chan MD. Surgical resection and postoperative radiosurgery versus staged radiosurgery for large brain metastases. J Neurooncol. 2018 Dec; 140(3):749-756. PMID: 30367382.
      View in: PubMed
    6. Fu H, Xing F, Lv Y, Zeng B, You P, Liu J. ICBP90 mediates Notch signaling to facilitate human hepatocellular carcinoma growth. Tissue Cell. 2018 Oct; 54:65-71. PMID: 30309512.
      View in: PubMed
    7. Xing F, Liu Y, Wu SY, Wu K, Sharma S, Mo YY, Feng J, Sanders S, Jin G, Singh R, Vidi PA, Tyagi A, Chan MD, Ruiz J, Debinski W, Pasche BC, Lo HW, Metheny-Barlow LJ, D'Agostino RB, Watabe K. Loss of XIST in Breast Cancer Activates MSN-c-Met and Reprograms Microglia via Exosomal miRNA to Promote Brain Metastasis. Cancer Res. 2018 08 01; 78(15):4316-4330. PMID: 30026327.
      View in: PubMed
    8. Xing F, Liu Y, Sharma S, Wu K, Chan MD, Lo HW, Carpenter RL, Metheny-Barlow LJ, Zhou X, Qasem SA, Pasche B, Watabe K. Activation of the c-Met Pathway Mobilizes an Inflammatory Network in the Brain Microenvironment to Promote Brain Metastasis of Breast Cancer. Cancer Res. 2016 09 01; 76(17):4970-80. PMID: 27364556.
      View in: PubMed
    9. Zeng C, Xing R, Liu J, Xing F. Role of CSL-dependent and independent Notch signaling pathways in cell apoptosis. Apoptosis. 2016 Jan; 21(1):1-12. PMID: 26496776.
      View in: PubMed
    10. Wu K, Fukuda K, Xing F, Zhang Y, Sharma S, Liu Y, Chan MD, Zhou X, Qasem SA, Pochampally R, Mo YY, Watabe K. Roles of the cyclooxygenase 2 matrix metalloproteinase 1 pathway in brain metastasis of breast cancer. J Biol Chem. 2015 Apr 10; 290(15):9842-54. PMID: 25691572.
      View in: PubMed
    11. Wang Y, Xing F, Ye S, Xiao J, Di J, Zeng S, Liu J. Jagged-1 signaling suppresses the IL-6 and TGF-ß treatment-induced Th17 cell differentiation via the reduction of ROR?t/IL-17A/IL-17F/IL-23a/IL-12rb1. Sci Rep. 2015 Feb 04; 5:8234. PMID: 25648768.
      View in: PubMed
    12. Xing F, Kobayashi A, Okuda H, Watabe M, Pai SK, Pandey PR, Hirota S, Wilber A, Mo YY, Moore BE, Liu W, Fukuda K, Iiizumi M, Sharma S, Liu Y, Wu K, Peralta E, Watabe K. Reactive astrocytes promote the metastatic growth of breast cancer stem-like cells by activating Notch signalling in brain. EMBO Mol Med. 2013 Mar; 5(3):384-96. PMID: 23495140.
      View in: PubMed
    13. Okuda H, Xing F, Pandey PR, Sharma S, Watabe M, Pai SK, Mo YY, Iiizumi-Gairani M, Hirota S, Liu Y, Wu K, Pochampally R, Watabe K. miR-7 suppresses brain metastasis of breast cancer stem-like cells by modulating KLF4. Cancer Res. 2013 Feb 15; 73(4):1434-44. PMID: 23384942.
      View in: PubMed
    14. Yu C, Xing F, Tang Z, Bronner C, Lu X, Di J, Zeng S, Liu J. Anisomycin suppresses Jurkat T cell growth by the cell cycle-regulating proteins. Pharmacol Rep. 2013; 65(2):435-44. PMID: 23744428.
      View in: PubMed
    15. Liu W, Xing F, Iiizumi-Gairani M, Okuda H, Watabe M, Pai SK, Pandey PR, Hirota S, Kobayashi A, Mo YY, Fukuda K, Li Y, Watabe K. N-myc downstream regulated gene 1 modulates Wnt-ß-catenin signalling and pleiotropically suppresses metastasis. EMBO Mol Med. 2012 Feb; 4(2):93-108. PMID: 22246988.
      View in: PubMed
    16. Kobayashi A, Okuda H, Xing F, Pandey PR, Watabe M, Hirota S, Pai SK, Liu W, Fukuda K, Chambers C, Wilber A, Watabe K. Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone. J Exp Med. 2011 Dec 19; 208(13):2641-55. PMID: 22124112.
      View in: PubMed
    17. Xing F, Okuda H, Watabe M, Kobayashi A, Pai SK, Liu W, Pandey PR, Fukuda K, Hirota S, Sugai T, Wakabayshi G, Koeda K, Kashiwaba M, Suzuki K, Chiba T, Endo M, Mo YY, Watabe K. Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells. Oncogene. 2011 Sep 29; 30(39):4075-86. PMID: 21499308.
      View in: PubMed
    18. Wang YF, Cai DH, Chen H, Mo YY, Yi N, Xing FY. [An infrared imaging system for detecting electrophoretic mobility shift of DNA-protein complexes]. Nan Fang Yi Ke Da Xue Xue Bao. 2009 Feb; 29(2):289-91. PMID: 19246302.
      View in: PubMed
    19. Fang ZY, Xing FY, Guo ZF, Chen L. [Effect of Jagged-1 on the cytokine expression of murine myeloid-derived dendritic cells]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2009 Feb; 25(2):100-3. PMID: 19174003.
      View in: PubMed
    20. Wang JK, Hu MQ, Xing FY. [Effect of Jagged1 on the morphology of DC differentiation observed by atomic force microscopy]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2008 Oct; 24(10):969-71. PMID: 18845081.
      View in: PubMed
    21. Xing F, Liu J, Mo Y, Liu Z, Qin Q, Wang J, Fan Z, Long Y, Liu N, Zhao K, Jiang Y. Lysophosphatidylcholine up-regulates human endothelial nitric oxide synthase gene transactivity by c-Jun N-terminal kinase signalling pathway. J Cell Mol Med. 2009 Jun; 13(6):1136-48. PMID: 18624763.
      View in: PubMed
    22. Xing FY, Yu Z, Liu J, Ji YH. [Effect of a soluble Jagged 1/Fc chimera protein on the activation, proliferation and cell cycle of lymphocytes in mice]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2008 Jan; 24(1):6-9. PMID: 18177607.
      View in: PubMed
    23. Xing F, Jiang Y, Liu J, Zhao K, Mo Y, Liu Z, Zeng Y. Downregulation of human endothelial nitric oxide synthase promoter activity by p38 mitogen-activated protein kinase activation. Biochem Cell Biol. 2006 Oct; 84(5):780-8. PMID: 17167542.
      View in: PubMed
    24. Xing F, Jiang Y, Liu J, Zhao K, Mo Y, Qin Q, Wang J, Ouyang J, Zeng Y. Role of AP1 element in the activation of human eNOS promoter by lysophosphatidylcholine. J Cell Biochem. 2006 Jul 01; 98(4):872-84. PMID: 16453281.
      View in: PubMed
    25. Zhang LH, Jia YH, Sun XG, Xing FY, Liu ZF, Song G, Jiang Y. [Effect of total Panax notoginseng saponins on the activity of human endothelial nitric oxide synthase gene promoter]. Di Yi Jun Yi Da Xue Xue Bao. 2004 Oct; 24(10):1113-6. PMID: 15485778.
      View in: PubMed
    26. Mo YY, Xing FY, Zhang B, Hen Y, Jiang Y. [Effect of astrocyte-conditioned medium on tert-butyl hydroperoxide-induced apoptosis of PC12 cells]. Di Yi Jun Yi Da Xue Xue Bao. 2004 Sep; 24(9):999-1000. PMID: 15447845.
      View in: PubMed
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