"Anesthetics, Local" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
| Descriptor ID |
D000779
|
| MeSH Number(s) |
D27.505.696.277.100.200 D27.505.696.663.850.025 D27.505.954.427.210.100.200
|
| Concept/Terms |
Anesthetics, Local- Anesthetics, Local
- Local Anesthetics
- Conduction-Blocking Anesthetics
- Conduction Blocking Anesthetics
- Anesthetics, Conduction-Blocking
- Anesthetics, Conduction Blocking
|
Below are MeSH descriptors whose meaning is more general than "Anesthetics, Local".
Below are MeSH descriptors whose meaning is more specific than "Anesthetics, Local".
This graph shows the total number of publications written about "Anesthetics, Local" by people in this website by year, and whether "Anesthetics, Local" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 4 | 0 | 4 |
| 2002 | 2 | 0 | 2 |
| 2003 | 3 | 0 | 3 |
| 2004 | 4 | 2 | 6 |
| 2005 | 0 | 3 | 3 |
| 2007 | 0 | 4 | 4 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 4 | 0 | 4 |
| 2013 | 2 | 0 | 2 |
| 2014 | 2 | 1 | 3 |
| 2015 | 2 | 1 | 3 |
| 2016 | 7 | 0 | 7 |
| 2017 | 0 | 1 | 1 |
| 2018 | 3 | 1 | 4 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 2 | 3 |
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Below are the most recent publications written about "Anesthetics, Local" by people in Profiles.