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Orr, Miranda

One or more keywords matched the following items that are connected to Orr, Miranda

Item Type	Name
Concept	Alzheimer Disease
Concept	Neurodegenerative Diseases
Concept	Disease Models, Animal
Concept	Disease Progression
Academic Article	Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3+ progenitors and peripheral neurons.
Academic Article	Accumulation of C-terminal fragments of transactive response DNA-binding protein 43 leads to synaptic loss and cognitive deficits in human TDP-43 transgenic mice.
Academic Article	Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology.
Academic Article	Autophagic/lysosomal dysfunction in Alzheimer's disease.
Academic Article	Mammalian Target of Rapamycin at the Crossroad Between Alzheimer's Disease and Diabetes.
Academic Article	Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent.
Academic Article	Tau protein aggregation is associated with cellular senescence in the brain.
Grant	Novel Stem Cell and Mouse Models to Study Frontotemporal Dementia
Grant	Alzheimer's Disease Associated Tau Toxicity Induces Cellular Senescence in Brain
Grant	High Resolution Profiling of Senescent Neurons and Their Microenvironments in Postmortem Human Brain Tissue Spanning Eight Decades of Life
Academic Article	Aging-related Alzheimer's disease-like neuropathology and functional decline in captive vervet monkeys (Chlorocebus aethiops sabaeus).
Grant	Development of an Innovative Vervet (Chlorocebus aethiops sabaeus) Model of Early Alzheimer's-like Neuropathology and Symptomatology
Grant	Cell Senescence and Death in Neurodegenerative Diseases
Grant	Phase II Clinical Trial to Evaluate the Safety and Feasibility of Senolytic Therapy in Alzheimer’s Disease
Grant	Evaluating microtubule binding as a potential imaging biomarker for Alzheimer's disease
Grant	Alzheimer’s disease-associated tau toxicity induces cellular senescence in the brain.
Academic Article	Biological aging processes underlying cognitive decline and neurodegenerative disease.
Academic Article	Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer's disease: review, recommendation, implementation and application.
Academic Article	Differential protein expression in the hippocampi of resilient individuals identified by digital spatial profiling.
Academic Article	Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD): A Pilot Clinical Trial.
Academic Article	A geroscience motivated approach to treat Alzheimer's disease: Senolytics move to clinical trials.
Academic Article	Can oral health and oral-derived biospecimens predict progression of dementia?

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