| Item Type | Name |
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Concept
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Ubiquitin-Protein Ligases
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Concept
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Oncogene Protein v-akt
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Concept
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Cyclic AMP Response Element-Binding Protein
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Concept
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SKP Cullin F-Box Protein Ligases
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Concept
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Mitogen-Activated Protein Kinase 1
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Concept
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Protein Biosynthesis
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Concept
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Protein-Serine-Threonine Kinases
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Concept
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AMP-Activated Protein Kinases
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Concept
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Mitogen-Activated Protein Kinase 3
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Concept
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Protein Processing, Post-Translational
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Concept
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p38 Mitogen-Activated Protein Kinases
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Concept
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Von Hippel-Lindau Tumor Suppressor Protein
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Academic Article
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PAS kinase is required for normal cellular energy balance.
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Academic Article
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Early mitochondrial adaptations in skeletal muscle to diet-induced obesity are strain dependent and determine oxidative stress and energy expenditure but not insulin sensitivity.
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Academic Article
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Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase.
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Academic Article
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Protein modification by O-linked GlcNAc reduces angiogenesis by inhibiting Akt activity in endothelial cells.
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Academic Article
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Iron-mediated inhibition of mitochondrial manganese uptake mediates mitochondrial dysfunction in a mouse model of hemochromatosis.
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Academic Article
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Adipocyte iron regulates adiponectin and insulin sensitivity.
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Academic Article
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Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: a role for HIF in glucose metabolism.
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Academic Article
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Saturated fatty acids inhibit hepatic insulin action by modulating insulin receptor expression and post-receptor signalling.
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Academic Article
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Regulation of Akt signaling by O-GlcNAc in euglycemia.
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Academic Article
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Oxidative stress, beta-cell apoptosis, and decreased insulin secretory capacity in mouse models of hemochromatosis.
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Academic Article
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Cardiac expression of kinase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase inhibits glycolysis, promotes hypertrophy, impairs myocyte function, and reduces insulin sensitivity.
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Academic Article
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Up-regulation of O-GlcNAc transferase with glucose deprivation in HepG2 cells is mediated by decreased hexosamine pathway flux.
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Academic Article
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Iron regulates glucose homeostasis in liver and muscle via AMP-activated protein kinase in mice.
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Academic Article
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Contribution of insulin and Akt1 signaling to endothelial nitric oxide synthase in the regulation of endothelial function and blood pressure.
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Academic Article
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Iron overload and diabetes risk: a shift from glucose to Fatty Acid oxidation and increased hepatic glucose production in a mouse model of hereditary hemochromatosis.
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Academic Article
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Downregulation of E3 ubiquitin ligases and mitophagy-related genes in skeletal muscle of physically inactive, frail older women: a cross-sectional comparison.
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Academic Article
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Pleiotropic and age-dependent effects of decreased protein modification by O-linked N-acetylglucosamine on pancreatic ß-cell function and vascularization.
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Academic Article
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Skeletal muscle Ras-related GTP binding B mRNA and protein expression is increased after essential amino acid ingestion in healthy humans.
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Academic Article
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Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression.
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Academic Article
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Chronic hexosamine flux stimulates fatty acid oxidation by activating AMP-activated protein kinase in adipocytes.
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Academic Article
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Adipocyte iron regulates leptin and food intake.
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Grant
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Hexosamines, Glucose Toxicity and Insulin Resistance
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Academic Article
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Iron down-regulates leptin by suppressing protein O-GlcNAc modification in adipocytes, resulting in decreased levels of O-glycosylated CREB.
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Grant
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Mechanism of Integrative Metabolic Regulation by Iron and Hypoxia
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