| Item Type | Name |
|
Concept
|
Mice, Knockout
|
|
Concept
|
Mice
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Mice, Obese
|
|
Concept
|
Mice, Mutant Strains
|
|
Academic Article
|
PAS kinase is required for normal cellular energy balance.
|
|
Academic Article
|
A role for the transcriptional coactivator PGC-1alpha in muscle refueling.
|
|
Academic Article
|
Early mitochondrial adaptations in skeletal muscle to diet-induced obesity are strain dependent and determine oxidative stress and energy expenditure but not insulin sensitivity.
|
|
Academic Article
|
Increased glucose disposal and AMP-dependent kinase signaling in a mouse model of hemochromatosis.
|
|
Academic Article
|
Protein modification by O-linked GlcNAc reduces angiogenesis by inhibiting Akt activity in endothelial cells.
|
|
Academic Article
|
Iron-mediated inhibition of mitochondrial manganese uptake mediates mitochondrial dysfunction in a mouse model of hemochromatosis.
|
|
Academic Article
|
Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance.
|
|
Academic Article
|
Systemic PPAR? deletion impairs circadian rhythms of behavior and metabolism.
|
|
Academic Article
|
MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity.
|
|
Academic Article
|
Adipocyte iron regulates adiponectin and insulin sensitivity.
|
|
Academic Article
|
Hyperglycemia and inhibition of glycogen synthase in streptozotocin-treated mice: role of O-linked N-acetylglucosamine.
|
|
Academic Article
|
Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: a role for HIF in glucose metabolism.
|
|
Academic Article
|
Saturated fatty acids inhibit hepatic insulin action by modulating insulin receptor expression and post-receptor signalling.
|
|
Academic Article
|
Regulation of Akt signaling by O-GlcNAc in euglycemia.
|
|
Academic Article
|
Oxidative stress, beta-cell apoptosis, and decreased insulin secretory capacity in mouse models of hemochromatosis.
|
|
Academic Article
|
Cardiac expression of kinase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase inhibits glycolysis, promotes hypertrophy, impairs myocyte function, and reduces insulin sensitivity.
|
|
Academic Article
|
Manganese supplementation protects against diet-induced diabetes in wild type mice by enhancing insulin secretion.
|
|
Academic Article
|
Overexpression of nuclear receptor SHP in adipose tissues affects diet-induced obesity and adaptive thermogenesis.
|
|
Academic Article
|
Adipocytes with increased hexosamine flux exhibit insulin resistance, increased glucose uptake, and increased synthesis and storage of lipid.
|
|
Academic Article
|
Iron regulates glucose homeostasis in liver and muscle via AMP-activated protein kinase in mice.
|
|
Academic Article
|
Dietary iron restriction or iron chelation protects from diabetes and loss of beta-cell function in the obese (ob/ob lep-/-) mouse.
|
|
Academic Article
|
The role of mPer2 clock gene in glucocorticoid and feeding rhythms.
|
|
Academic Article
|
Analysis of hepatic glycogen-associated proteins.
|
|
Academic Article
|
Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity.
|
|
Academic Article
|
Regulation of fatty acid metabolism by mTOR in adult murine hearts occurs independently of changes in PGC-1a.
|
|
Academic Article
|
Contribution of insulin and Akt1 signaling to endothelial nitric oxide synthase in the regulation of endothelial function and blood pressure.
|
|
Academic Article
|
Increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathway.
|
|
Academic Article
|
Hexosamines regulate sensitivity of glucose-stimulated insulin secretion in beta-cells.
|
|
Academic Article
|
Iron overload and diabetes risk: a shift from glucose to Fatty Acid oxidation and increased hepatic glucose production in a mouse model of hereditary hemochromatosis.
|
|
Academic Article
|
Pleiotropic and age-dependent effects of decreased protein modification by O-linked N-acetylglucosamine on pancreatic ß-cell function and vascularization.
|
|
Academic Article
|
Hexosamines as mediators of nutrient sensing and regulation in diabetes.
|
|
Academic Article
|
Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression.
|
|
Academic Article
|
Chronic hexosamine flux stimulates fatty acid oxidation by activating AMP-activated protein kinase in adipocytes.
|
|
Academic Article
|
Transgenic mice overexpressing the rate-limiting enzyme for hexosamine synthesis in skeletal muscle or adipose tissue exhibit total body insulin resistance.
|
|
Academic Article
|
Dietary iron controls circadian hepatic glucose metabolism through heme synthesis.
|
|
Academic Article
|
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia.
|
|
Academic Article
|
Recipes for creating animal models of diabetic cardiovascular disease.
|
|
Academic Article
|
Insulin resistance of glycogen synthase mediated by o-linked N-acetylglucosamine.
|
|
Academic Article
|
MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling, and glucose intolerance.
|
|
Academic Article
|
Adipocyte iron regulates leptin and food intake.
|
|
Academic Article
|
Synergistic Inhibitory Effects of Hypoxia and Iron Deficiency on Hepatic Glucose Response in Mouse Liver.
|
|
Grant
|
Iron And Metabolism: Altered Fuel Oxidation And Mitochondrial Dysfunction
|
|
Grant
|
Hexosamines, Glucose Toxicity and Insulin Resistance
|
|
Grant
|
DIABETES IN HEMOCHROMATOSIS: PREVALENCE AND MECHANISMS
|
|
Grant
|
Diabetes in Hemochromatosis: Prevalence and Mechanisms
|
|
Academic Article
|
Comparative Microbiome Signatures and Short-Chain Fatty Acids in Mouse, Rat, Non-human Primate, and Human Feces.
|
|
Grant
|
Iron Reduction for the Treatment of Diabetes and Nonalcoholic Fatty Liver Disease
|
|
Academic Article
|
Iron down-regulates leptin by suppressing protein O-GlcNAc modification in adipocytes, resulting in decreased levels of O-glycosylated CREB.
|
|
Grant
|
Mechanism of Integrative Metabolic Regulation by Iron and Hypoxia
|