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Kridel, Steven

One or more keywords matched the following properties of Kridel, Steven

Property	Value
first name	Steven
full name	Steven J. Kridel PhD
label	Kridel, Steven

One or more keywords matched the following items that are connected to Kridel, Steven

Item Type	Name
Academic Article	A substrate phage enzyme-linked immunosorbent assay to profile panels of proteases.
Academic Article	A unique substrate recognition profile for matrix metalloproteinase-2.
Academic Article	A unique substrate binding mode discriminates membrane type-1 matrix metalloproteinase from other matrix metalloproteinases.
Academic Article	Fatty acid synthase: a novel target for antiglioma therapy.
Academic Article	Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat.
Academic Article	Identification and biological evaluation of a novel and potent small molecule radiation sensitizer via an unbiased screen of a chemical library.
Academic Article	1-11C-acetate as a PET radiopharmaceutical for imaging fatty acid synthase expression in prostate cancer.
Academic Article	Disruption of crosstalk between the fatty acid synthesis and proteasome pathways enhances unfolded protein response signaling and cell death.
Academic Article	Nicotinamide phosphoribosyl transferase (Nampt) is required for de novo lipogenesis in tumor cells.
Academic Article	Substrate hydrolysis by matrix metalloproteinase-9.
Academic Article	S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death.
Academic Article	Orlistat is a novel inhibitor of fatty acid synthase with antitumor activity.
Academic Article	Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells.
Academic Article	Dietary fat-gene interactions in cancer.
Academic Article	Fatty acid synthase inhibitors: new directions for oncology.
Academic Article	Fatty acid synthase activity in tumor cells.
Academic Article	Preferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways.
Academic Article	An interleukin 13 receptor a 2-specific peptide homes to human Glioblastoma multiforme xenografts.
Academic Article	Polyunsaturated fatty acid metabolism in prostate cancer.
Academic Article	Metabolic regulation of invadopodia and invasion by acetyl-CoA carboxylase 1 and de novo lipogenesis.
Academic Article	The potential of ¹¹C-acetate PET for monitoring the Fatty acid synthesis pathway in Tumors.
Academic Article	Requirement of lysine residues outside of the proposed pentasaccharide binding region for high affinity heparin binding and activation of human antithrombin III.
Academic Article	Lysine residue 114 in human antithrombin III is required for heparin pentasaccharide-mediated activation.
Concept	Hematopoietic Stem Cells
Concept	Protein Structure, Tertiary
Concept	Catalytic Domain
Concept	Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Concept	Protein Stability
Concept	Binding Sites
Concept	Computer Simulation
Concept	Fatty Acid Synthesis Inhibitors
Concept	Amino Acid Sequence
Concept	Stress, Physiological
Concept	Organ Specificity
Concept	Nitric Oxide Synthase
Concept	Drug Synergism
Concept	Signal Transduction
Concept	Bile Acids and Salts
Concept	Gene Expression Profiling
Concept	RNA, Small Interfering
Concept	Heat-Shock Proteins
Concept	Genetic Association Studies
Concept	Prostaglandin-Endoperoxide Synthases
Concept	Sulfhydryl Compounds
Concept	Mutagenesis, Site-Directed
Concept	Polymorphism, Single Nucleotide
Concept	Cell Survival
Concept	Sirtuins
Concept	DNA Breaks, Double-Stranded
Concept	S-Nitrosothiols
Concept	Nitric Oxide Synthase Type I
Concept	Sequence Homology, Amino Acid
Concept	Radiation-Sensitizing Agents
Concept	Substrate Specificity
Concept	Cell Surface Extensions
Concept	Genes, src
Concept	Structure-Activity Relationship
Concept	Secretory Pathway
Concept	Interleukin-13 Receptor alpha2 Subunit
Concept	Base Sequence
Concept	Molecular Sequence Data
Academic Article	Fatty acid synthase is required for mammary gland development and milk production during lactation.
Academic Article	Inhibition of the thioesterase activity of human fatty acid synthase by 1,4- and 9,10-diones.
Academic Article	A Comprehensive Analysis of Common and Rare Variants to Identify Adiposity Loci in Hispanic Americans: The IRAS Family Study (IRASFS).
Academic Article	Development of a Self-Assembled Nanoparticle Formulation of Orlistat, Nano-ORL, with Increased Cytotoxicity against Human Tumor Cell Lines.
Academic Article	Crystal Structure and Substrate Specificity of Human Thioesterase 2: INSIGHTS INTO THE MOLECULAR BASIS FOR THE MODULATION OF FATTY ACID SYNTHASE.
Academic Article	Yin Yang 1 promotes mTORC2-mediated AKT phosphorylation.
Academic Article	Palmitoylation regulates the intracellular trafficking and stability of c-Met.
Academic Article	Fatty acid synthase is a primary target of MiR-15a and MiR-16-1 in breast cancer.
Grant	Training Program in Cancer Biology
Grant	NAD+ metabolism in prostate cancer
Grant	Fatty acid synthase inhibitors and prostate cancer
Academic Article	Combination Treatment with Orlistat-Containing Nanoparticles and Taxanes Is Synergistic and Enhances Microtubule Stability in Taxane-Resistant Prostate Cancer Cells.
Academic Article	Atad3a suppresses Pink1-dependent mitophagy to maintain homeostasis of hematopoietic progenitor cells.
Academic Article	CD38 Inhibits Prostate Cancer Metabolism and Proliferation by Reducing Cellular NAD+ Pools.
Grant	Training program to promote diversity in cancer research
Academic Article	SPARC Inhibits Metabolic Plasticity in Ovarian Cancer.

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