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Parks, John

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Item Type	Name
Academic Article	Dietary n-3 polyunsaturated fat increases the fractional catabolic rate of medium-sized HDL particles in African green monkeys.
Academic Article	Alteration of plasma HDL cholesteryl ester composition with transgenic expression of a point mutation (E149A) of human LCAT.
Academic Article	Lecithin:cholesterol acyltransferase deficiency increases atherosclerosis in the low density lipoprotein receptor and apolipoprotein E knockout mice.
Academic Article	Dietary fish oil effects on biliary lipid secretion and cholesterol gallstone formation in the African green monkey.
Academic Article	Reduced proteoglycan binding of low density lipoproteins from monkeys (Macaca fascicularis) fed a fish oil versus lard diet.
Academic Article	Isolation and characterization of high density lipoprotein apoproteins in the non-human primate (vervet).
Academic Article	Dietary hydrogenated fat increases high-density lipoprotein apoA-I catabolism and decreases low-density lipoprotein apoB-100 catabolism in hypercholesterolemic women.
Academic Article	Studies on the effect of dietary fish oil on the physical and chemical properties of low density lipoproteins in cynomolgus monkeys.
Academic Article	ACAT2 contributes cholesteryl esters to newly secreted VLDL, whereas LCAT adds cholesteryl ester to LDL in mice.
Academic Article	Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I.
Academic Article	HDLs in apoA-I transgenic Abca1 knockout mice are remodeled normally in plasma but are hypercatabolized by the kidney.
Academic Article	Oral contraceptives, lipoproteins, and atherosclerosis.
Academic Article	Inhibition of coronary artery atherosclerosis by 17-beta estradiol in ovariectomized monkeys. Lack of an effect of added progesterone.
Academic Article	Effect of dietary fish oil on coronary artery and aortic atherosclerosis in African green monkeys.
Academic Article	Reduction in ABCG1 in Type 2 diabetic mice increases macrophage foam cell formation.
Academic Article	Fish oil decreases hepatic cholesteryl ester secretion but not apoB secretion in African green monkeys.
Academic Article	Targeted deletion of hepatocyte ABCA1 leads to very low density lipoprotein triglyceride overproduction and low density lipoprotein hypercatabolism.
Academic Article	Adipose tissue ATP binding cassette transporter A1 contributes to high-density lipoprotein biogenesis in vivo.
Academic Article	Hepatic ABCA1 and VLDL triglyceride production.
Academic Article	Contraceptive steroid effects on lipids and lipoproteins in cynomolgus monkeys.
Academic Article	Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis.
Academic Article	Lecithin:cholesterol acyltransferase-induced modifications of liver perfusate discoidal high density lipoproteins from African green monkeys.
Academic Article	Effect of fish oil versus lard diets on the chemical and physical properties of low density lipoproteins of nonhuman primates.
Academic Article	Alteration of high density lipoprotein subfraction distribution with induction of serum amyloid A protein (SAA) in the nonhuman primate.
Academic Article	Different kinetic fates of apolipoproteins A-I and A-II from lymph chylomicra of nonhuman primates. Effect of saturated versus polyunsaturated dietary fat.
Academic Article	Physical characterization of lymph chylomicrons and very low density lipoproteins from nonhuman primates fed saturated dietary fat.
Academic Article	Dietary polyunsaturated fat modifies low-density lipoproteins and reduces atherosclerosis of nonhuman primates with high and low diet responsiveness.
Academic Article	ACAT inhibitors CL 283,546 and CL 283,796 reduce LDL cholesterol without affecting cholesterol absorption in African green monkeys.
Academic Article	Dietary fatty acid modification of HDL phospholipid molecular species alters lecithin: cholesterol acyltransferase reactivity in cynomolgus monkeys.
Academic Article	Dietary polyunsaturated fat decreases interaction between low density lipoproteins and arterial proteoglycans.
Academic Article	Dietary fish oil-induced decrease in low density lipoprotein binding to fibroblasts is mediated by apolipoprotein E.
Academic Article	Effect of interleukin-1 alpha on lipoprotein lipids in cynomolgus monkeys: comparison to tumor necrosis factor.
Academic Article	Lipoprotein lipase enhances the interaction of low density lipoproteins with artery-derived extracellular matrix proteoglycans.
Academic Article	Dietary fish oil modification of cynomolgus monkey low density lipoproteins results in decreased binding and cholesteryl ester accumulation by cultured fibroblasts.
Academic Article	Plasma cholesteryl ester transfer activity is modulated by the phase transition of the lipoprotein core.
Academic Article	Long-chain polyunsaturated fatty acids in the sn-2 position of phosphatidylcholine decrease the stability of recombinant high density lipoprotein apolipoprotein A-I and the activation energy of the lecithin:cholesterol acyltransferase reaction.
Academic Article	Cloning and in vitro expression of rat lecithin:cholesterol acyltransferase.
Academic Article	Small HDL particles containing two apoA-I molecules are precursors in vivo to medium and large HDL particles containing three and four apoA-I molecules in nonhuman primates.
Academic Article	Phosphatidylcholine fluidity and structure affect lecithin:cholesterol acyltransferase activity.
Academic Article	ApoA-I secretion from HepG2 cells: evidence for the secretion of both lipid-poor apoA-I and intracellularly assembled nascent HDL.
Academic Article	In vivo contribution of LCAT to apolipoprotein B lipoprotein cholesteryl esters in LDL receptor and apolipoprotein E knockout mice.
Academic Article	Age and dietary polyunsaturated fat alter high density lipoprotein subfraction cholesterol concentrations in a pediatric population of African green monkeys.
Academic Article	Enhancement of scavenger receptor class B type I-mediated selective cholesteryl ester uptake from apoA-I(-/-) high density lipoprotein (HDL) by apolipoprotein A-I requires HDL reorganization by lecithin cholesterol acyltransferase.
Academic Article	Identification of the lipoprotein initiating domain of apolipoprotein B.
Academic Article	Harmful effects of increased LDLR expression in mice with human APOE4 but not APOE3.
Academic Article	Compared with Acyl-CoA:cholesterol O-acyltransferase (ACAT) 1 and lecithin:cholesterol acyltransferase, ACAT2 displays the greatest capacity to differentiate cholesterol from sitosterol.
Academic Article	Prebeta high density lipoprotein has two metabolic fates in human apolipoprotein A-I transgenic mice.
Academic Article	ATP-binding cassette transporter AI and its role in HDL formation.
Academic Article	Apolipoprotein E is the major physiological activator of lecithin-cholesterol acyltransferase (LCAT) on apolipoprotein B lipoproteins.
Academic Article	Hepatic ATP-binding cassette transporter A1 is a key molecule in high-density lipoprotein cholesteryl ester metabolism in mice.
Academic Article	Effect of fish oil on atherosclerosis and lipoprotein metabolism.
Academic Article	Both hepatic and extrahepatic ABCA1 have discrete and essential functions in the maintenance of plasma high-density lipoprotein cholesterol levels in vivo.
Academic Article	Effect of fish oil diet on hepatic lipid metabolism in nonhuman primates: lowering of secretion of hepatic triglyceride but not apoB.
Academic Article	A rapid and sensitive micro-assay for the enzymatic determination of plasma and lipoprotein cholesterol.
Academic Article	Minimal lipidation of pre-beta HDL by ABCA1 results in reduced ability to interact with ABCA1.
Academic Article	Lipopolysaccharide and tumor necrosis factor cause a fall in plasma concentration of lecithin: cholesterol acyltransferase in cynomolgus monkeys.
Academic Article	Initial interaction of apoA-I with ABCA1 impacts in vivo metabolic fate of nascent HDL.
Academic Article	LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins.
Academic Article	Apolipoprotein M expression increases the size of nascent pre beta HDL formed by ATP binding cassette transporter A1.
Academic Article	ATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation.
Academic Article	ABCG1 deficiency in mice promotes endothelial activation and monocyte-endothelial interactions.
Academic Article	A novel role for ABCA1-generated large pre-beta migrating nascent HDL in the regulation of hepatic VLDL triglyceride secretion.
Academic Article	Lipoprotein abnormalities associated with lipopolysaccharide-induced lecithin: cholesterol acyltransferase and lipase deficiency.
Academic Article	Apolipoprotein L1 nephropathy risk variants associate with HDL subfraction concentration in African Americans.
Academic Article	New roles of HDL in inflammation and hematopoiesis.
Academic Article	Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers.
Academic Article	ATP-binding cassette transporter G1 intrinsically regulates invariant NKT cell development.
Academic Article	Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration.
Academic Article	Low density lipoproteins in atherosclerosis.
Academic Article	Studies of low density lipoprotein molecular weight in human beings with coronary artery disease.
Academic Article	Metabolism of the serum amyloid A proteins (SSA) in high-density lipoproteins and chylomicrons of nonhuman primates (vervet monkey).
Academic Article	1H NMR studies of lymph chylomicra and very low density lipoproteins from nonhuman primates.
Academic Article	Compared with dietary monounsaturated and saturated fat, polyunsaturated fat protects African green monkeys from coronary artery atherosclerosis.
Academic Article	Lipid metabolism.
Academic Article	Interrelationships of alpha-tocopherol with plasma lipoproteins in African green monkeys: effects of dietary fats.
Academic Article	High level secretion of wild-type and mutant forms of human proapoA-I using baculovirus-mediated Sf-9 cell expression.
Academic Article	Low density lipoprotein particle size and core cholesteryl ester physical state affect the proton NMR magnetic environment of fatty acid methylene and methyl nuclei.
Academic Article	Effects of hormone replacement modalities on low density lipoprotein composition and distribution in ovariectomized cynomolgus monkeys.
Academic Article	Effects of contraceptive estrogen and progestin on the atherogenic potential of plasma LDLs in cynomolgus monkeys.
Academic Article	The hydrophobic face orientation of apolipoprotein A-I amphipathic helix domain 143-164 regulates lecithin:cholesterol acyltransferase activation.
Academic Article	Effect of long chain polyunsaturated fatty acids in the sn-2 position of phosphatidylcholine on the interaction with recombinant high density lipoprotein apolipoprotein A-I.
Academic Article	Lecithin-cholesterol acyltransferase. Assay of cholesterol esterification and phospholipase A2 activities.
Academic Article	Lipoprotein and cholesterol metabolism in diet-induced coronary artery atherosclerosis in primates. Role of cholesterol and fatty acids.
Academic Article	Determination of the tissue sites responsible for the catabolism of large high density lipoprotein in the African green monkey.
Academic Article	Low-dose contraceptive estrogen-progestin and coronary artery atherosclerosis of monkeys.
Concept	Lipoprotein Lipase
Concept	Lipoproteins, VLDL
Concept	Lipoproteins, HDL
Concept	Lipoproteins, IDL
Concept	Lipoproteins
Concept	High-Density Lipoproteins, Pre-beta
Concept	Lipoproteins, LDL
Academic Article	Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice.
Academic Article	Echium oil reduces plasma triglycerides by increasing intravascular lipolysis in apoB100-only low density lipoprotein (LDL) receptor knockout mice.
Academic Article	Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein.
Academic Article	An abundant dysfunctional apolipoprotein A1 in human atheroma.
Academic Article	Myeloid cell-specific ATP-binding cassette transporter A1 deletion has minimal impact on atherogenesis in atherogenic diet-fed low-density lipoprotein receptor knockout mice.
Academic Article	Dietary cholesterol promotes adipocyte hypertrophy and adipose tissue inflammation in visceral, but not in subcutaneous, fat in monkeys.
Academic Article	Localization of APOL1 protein and mRNA in the human kidney: nondiseased tissue, primary cells, and immortalized cell lines.
Academic Article	Uncleaved ApoM signal peptide is required for formation of large ApoM/sphingosine 1-phosphate (S1P)-enriched HDL particles.
Academic Article	Biogenesis and cytotoxicity of APOL1 renal risk variant proteins in hepatocytes and hepatoma cells.
Academic Article	Characterization of circulating APOL1 protein complexes in African Americans.
Academic Article	A Systematic Investigation of Structure/Function Requirements for the Apolipoprotein A-I/Lecithin Cholesterol Acyltransferase Interaction Loop of High-density Lipoprotein.
Academic Article	APOL1 Renal-Risk Variants Induce Mitochondrial Dysfunction.
Academic Article	Very Low Density Lipoprotein Assembly Is Required for cAMP-responsive Element-binding Protein H Processing and Hepatic Apolipoprotein A-IV Expression.
Grant	EFFECT OF N-3 FATTY ACIDS ON HDL LIPID INTERACTION
Grant	DIETARY PUFA AND HDL SUBFRACTION METABOLISM
Grant	Regulation of ApoB Lipoprotein Expansion and Hepatic Lipid Efflux by ApoA-IV
Grant	Hepatocyte Abca1, cholesterol trafficking, and lipid mobilization
Grant	Macrophage, ABCA1, Inflammation, and Atherosclerosis
Grant	ATHEROGENIC PROPERTIES OF LOW DENSITY LIPOPROTEINS
Grant	LCAT, Lipids, and Atherosclerosis
Grant	2016 Lipoprotein Metabolism Gordon Research Conference and Gordon Research Seminar
Academic Article	Hepatic ABCA1 deficiency is associated with delayed apolipoprotein B secretory trafficking and augmented VLDL triglyceride secretion.
Academic Article	Targeted Deletion of Hepatocyte Abca1 Increases Plasma HDL (High-Density Lipoprotein) Reverse Cholesterol Transport via the LDL (Low-Density Lipoprotein) Receptor.
Academic Article	Apolipoprotein M and Sphingosine-1-Phosphate Receptor 1 Promote the Transendothelial Transport of High-Density Lipoprotein.
Academic Article	Early time-restricted feeding improves high-density lipoprotein amount and function in nonhuman primates, without effects on body composition.

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Lipoproteins