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Parks, John

One or more keywords matched the following items that are connected to Parks, John

Item Type	Name
Academic Article	Dietary n-3 polyunsaturated fat increases the fractional catabolic rate of medium-sized HDL particles in African green monkeys.
Academic Article	Lecithin:cholesterol acyltransferase deficiency increases atherosclerosis in the low density lipoprotein receptor and apolipoprotein E knockout mice.
Academic Article	Isolation and characterization of high density lipoprotein apoproteins in the non-human primate (vervet).
Academic Article	Dietary hydrogenated fat increases high-density lipoprotein apoA-I catabolism and decreases low-density lipoprotein apoB-100 catabolism in hypercholesterolemic women.
Academic Article	Plasma cholesteryl esters provided by lecithin:cholesterol acyltransferase and acyl-coenzyme a:cholesterol acyltransferase 2 have opposite atherosclerotic potential.
Academic Article	ACAT2 contributes cholesteryl esters to newly secreted VLDL, whereas LCAT adds cholesteryl ester to LDL in mice.
Academic Article	Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I.
Academic Article	HDLs in apoA-I transgenic Abca1 knockout mice are remodeled normally in plasma but are hypercatabolized by the kidney.
Academic Article	Fish oil decreases hepatic cholesteryl ester secretion but not apoB secretion in African green monkeys.
Academic Article	Combined therapy of dietary fish oil and stearoyl-CoA desaturase 1 inhibition prevents the metabolic syndrome and atherosclerosis.
Academic Article	Alternative splicing attenuates transgenic expression directed by the apolipoprotein E promoter-enhancer based expression vector pLIV11.
Academic Article	Targeted deletion of hepatocyte ABCA1 leads to very low density lipoprotein triglyceride overproduction and low density lipoprotein hypercatabolism.
Academic Article	Myeloid differentiation primary response protein 88 couples reverse cholesterol transport to inflammation.
Academic Article	Adipose tissue ATP binding cassette transporter A1 contributes to high-density lipoprotein biogenesis in vivo.
Academic Article	Hepatic ABCA1 and VLDL triglyceride production.
Academic Article	Omega-3 fatty acids ameliorate atherosclerosis by favorably altering monocyte subsets and limiting monocyte recruitment to aortic lesions.
Academic Article	Alteration of high density lipoprotein subfraction distribution with induction of serum amyloid A protein (SAA) in the nonhuman primate.
Academic Article	Different kinetic fates of apolipoproteins A-I and A-II from lymph chylomicra of nonhuman primates. Effect of saturated versus polyunsaturated dietary fat.
Academic Article	ACAT inhibitors CL 283,546 and CL 283,796 reduce LDL cholesterol without affecting cholesterol absorption in African green monkeys.
Academic Article	Effect of apolipoprotein A-I deficiency on lecithin:cholesterol acyltransferase activation in mouse plasma.
Academic Article	Dietary polyunsaturated fat decreases interaction between low density lipoproteins and arterial proteoglycans.
Academic Article	Dietary fish oil-induced decrease in low density lipoprotein binding to fibroblasts is mediated by apolipoprotein E.
Academic Article	Cytokines decrease apolipoprotein accumulation in medium from Hep G2 cells.
Academic Article	Dietary fish oil modification of cynomolgus monkey low density lipoproteins results in decreased binding and cholesteryl ester accumulation by cultured fibroblasts.
Academic Article	Long-chain polyunsaturated fatty acids in the sn-2 position of phosphatidylcholine decrease the stability of recombinant high density lipoprotein apolipoprotein A-I and the activation energy of the lecithin:cholesterol acyltransferase reaction.
Academic Article	Influence of vesicle surface composition on the interfacial binding of lecithin:cholesterol acyltransferase and apolipoprotein A-I.
Academic Article	Small HDL particles containing two apoA-I molecules are precursors in vivo to medium and large HDL particles containing three and four apoA-I molecules in nonhuman primates.
Academic Article	Phosphatidylcholine fluidity and structure affect lecithin:cholesterol acyltransferase activity.
Academic Article	ApoA-I secretion from HepG2 cells: evidence for the secretion of both lipid-poor apoA-I and intracellularly assembled nascent HDL.
Academic Article	In vivo contribution of LCAT to apolipoprotein B lipoprotein cholesteryl esters in LDL receptor and apolipoprotein E knockout mice.
Academic Article	Age and dietary polyunsaturated fat alter high density lipoprotein subfraction cholesterol concentrations in a pediatric population of African green monkeys.
Academic Article	Transgenic overexpression of human lecithin: cholesterol acyltransferase (LCAT) in mice does not increase aortic cholesterol deposition.
Academic Article	Enhancement of scavenger receptor class B type I-mediated selective cholesteryl ester uptake from apoA-I(-/-) high density lipoprotein (HDL) by apolipoprotein A-I requires HDL reorganization by lecithin cholesterol acyltransferase.
Academic Article	Identification of the lipoprotein initiating domain of apolipoprotein B.
Academic Article	Harmful effects of increased LDLR expression in mice with human APOE4 but not APOE3.
Academic Article	Prebeta high density lipoprotein has two metabolic fates in human apolipoprotein A-I transgenic mice.
Academic Article	ATP-binding cassette transporter AI and its role in HDL formation.
Academic Article	Apolipoprotein E is the major physiological activator of lecithin-cholesterol acyltransferase (LCAT) on apolipoprotein B lipoproteins.
Academic Article	Both hepatic and extrahepatic ABCA1 have discrete and essential functions in the maintenance of plasma high-density lipoprotein cholesterol levels in vivo.
Academic Article	Functional LCAT deficiency in human apolipoprotein A-I transgenic, SR-BI knockout mice.
Academic Article	Effect of fish oil diet on hepatic lipid metabolism in nonhuman primates: lowering of secretion of hepatic triglyceride but not apoB.
Academic Article	Minimal lipidation of pre-beta HDL by ABCA1 results in reduced ability to interact with ABCA1.
Academic Article	Echium oil reduces plasma lipids and hepatic lipogenic gene expression in apoB100-only LDL receptor knockout mice.
Academic Article	Initial interaction of apoA-I with ABCA1 impacts in vivo metabolic fate of nascent HDL.
Academic Article	LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins.
Academic Article	Tissue-specific roles of ABCA1 influence susceptibility to atherosclerosis.
Academic Article	An innate immunity signaling process suppresses macrophage ABCA1 expression through IRAK-1-mediated downregulation of retinoic acid receptor alpha and NFATc2.
Academic Article	Apolipoprotein M expression increases the size of nascent pre beta HDL formed by ATP binding cassette transporter A1.
Academic Article	A novel role for ABCA1-generated large pre-beta migrating nascent HDL in the regulation of hepatic VLDL triglyceride secretion.
Academic Article	Apolipoprotein L1 nephropathy risk variants associate with HDL subfraction concentration in African Americans.
Academic Article	Echium oil reduces atherosclerosis in apoB100-only LDLrKO mice.
Academic Article	New roles of HDL in inflammation and hematopoiesis.
Academic Article	Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers.
Academic Article	Myeloid cell-specific ABCA1 deletion protects mice from bacterial infection.
Academic Article	Detection of immunological heterogeneity of an isolated, purified protein (vervet apolipoprotein A-I).
Academic Article	Metabolism of the serum amyloid A proteins (SSA) in high-density lipoproteins and chylomicrons of nonhuman primates (vervet monkey).
Academic Article	Compared with dietary monounsaturated and saturated fat, polyunsaturated fat protects African green monkeys from coronary artery atherosclerosis.
Academic Article	Interrelationships of alpha-tocopherol with plasma lipoproteins in African green monkeys: effects of dietary fats.
Academic Article	Decreased binding of apoA-I to phosphatidylcholine monolayers containing 22:6 n-3 in the sn-2 position.
Academic Article	High level secretion of wild-type and mutant forms of human proapoA-I using baculovirus-mediated Sf-9 cell expression.
Academic Article	Alteration in apolipoprotein A-I 22-mer repeat order results in a decrease in lecithin:cholesterol acyltransferase reactivity.
Academic Article	Effects of hormone replacement modalities on low density lipoprotein composition and distribution in ovariectomized cynomolgus monkeys.
Academic Article	Effects of contraceptive estrogen and progestin on the atherogenic potential of plasma LDLs in cynomolgus monkeys.
Academic Article	The hydrophobic face orientation of apolipoprotein A-I amphipathic helix domain 143-164 regulates lecithin:cholesterol acyltransferase activation.
Academic Article	Effect of long chain polyunsaturated fatty acids in the sn-2 position of phosphatidylcholine on the interaction with recombinant high density lipoprotein apolipoprotein A-I.
Academic Article	Lecithin-cholesterol acyltransferase. Assay of cholesterol esterification and phospholipase A2 activities.
Academic Article	Vesicle-binding properties of wild-type and cysteine mutant forms of alpha(1) domain of apolipoprotein B.
Concept	Apolipoprotein A-I
Concept	Apolipoprotein E4
Concept	Apolipoproteins C
Concept	Apolipoproteins
Concept	Apolipoprotein A-II
Concept	Apolipoproteins E
Concept	Apolipoprotein B-100
Concept	Apolipoproteins B
Concept	Apolipoproteins A
Concept	Apolipoprotein E3
Academic Article	Echium oil reduces plasma triglycerides by increasing intravascular lipolysis in apoB100-only low density lipoprotein (LDL) receptor knockout mice.
Academic Article	Liver ABCA1 deletion in LDLrKO mice does not impair macrophage reverse cholesterol transport or exacerbate atherogenesis.
Academic Article	Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein.
Academic Article	An abundant dysfunctional apolipoprotein A1 in human atheroma.
Academic Article	Localization of APOL1 protein and mRNA in the human kidney: nondiseased tissue, primary cells, and immortalized cell lines.
Academic Article	Uncleaved ApoM signal peptide is required for formation of large ApoM/sphingosine 1-phosphate (S1P)-enriched HDL particles.
Academic Article	Biogenesis and cytotoxicity of APOL1 renal risk variant proteins in hepatocytes and hepatoma cells.
Academic Article	Characterization of circulating APOL1 protein complexes in African Americans.
Academic Article	A Systematic Investigation of Structure/Function Requirements for the Apolipoprotein A-I/Lecithin Cholesterol Acyltransferase Interaction Loop of High-density Lipoprotein.
Academic Article	Myeloid Deletion of a1AMPK Exacerbates Atherosclerosis in LDL Receptor Knockout (LDLRKO) Mice.
Academic Article	APOL1 Renal-Risk Variants Induce Mitochondrial Dysfunction.
Academic Article	Very Low Density Lipoprotein Assembly Is Required for cAMP-responsive Element-binding Protein H Processing and Hepatic Apolipoprotein A-IV Expression.
Grant	Regulation of ApoB Lipoprotein Expansion and Hepatic Lipid Efflux by ApoA-IV
Grant	LCAT, Lipids, and Atherosclerosis
Academic Article	Hepatic ABCA1 deficiency is associated with delayed apolipoprotein B secretory trafficking and augmented VLDL triglyceride secretion.
Academic Article	Plasma apoM and S1P levels are inversely associated with mortality in African Americans with type 2 diabetes mellitus.
Academic Article	Reduced Apolipoprotein M and Adverse Outcomes Across the Spectrum of Human Heart Failure.
Academic Article	Apolipoprotein M and Sphingosine-1-Phosphate Receptor 1 Promote the Transendothelial Transport of High-Density Lipoprotein.
Academic Article	Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury.
Academic Article	APOL1 Risk Variants Impair Multiple Mitochondrial Pathways in a Metabolomics Analysis.

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Apolipoproteins