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Kucera, Gregory
One or more keywords matched the following items that are connected to Kucera, Gregory
Item TypeName
Academic Article Synthesis, biological activity, and DNA-damage profile of platinum-threading intercalator conjugates designed to target adenine.
Academic Article A non-cross-linking platinum-acridine agent with potent activity in non-small-cell lung cancer.
Academic Article Using a build-and-click approach for producing structural and functional diversity in DNA-targeted hybrid anticancer agents.
Academic Article Using fluorescent post-labeling to probe the subcellular localization of DNA-targeted platinum anticancer agents.
Academic Article Effect of the diamine nonleaving group in platinum-acridinylthiourea conjugates on DNA damage and cytotoxicity.
Academic Article Tuning the DNA conformational perturbations induced by cytotoxic platinum-acridine bisintercalators: effect of metal cis/trans isomerism and DNA threading groups.
Academic Article Effect of linkage geometry on biological activity in thiourea- and guanidine-substituted acridines and platinum-acridines.
Academic Article Synthesis and biological evaluation of platinum-acridine hybrid agents modified with bipyridine non-leaving groups.
Academic Article Gold(I) analogues of a platinum-acridine antitumor agent are only moderately cytotoxic but show potent activity against Mycobacterium tuberculosis.
Academic Article Probing platinum-adenine-n3 adduct formation with DNA minor-groove binding agents.
Academic Article Analysis of the DNA damage produced by a platinum-acridine antitumor agent and its effects in NCI-H460 lung cancer cells.
Academic Article Synthesis, aqueous reactivity, and biological evaluation of carboxylic acid ester-functionalized platinum-acridine hybrid anticancer agents.
Academic Article Design of a platinum-acridine-endoxifen conjugate targeted at hormone-dependent breast cancer.
Concept Platinum Compounds
Concept Platinum
Academic Article Investigating the cellular fate of a DNA-targeted platinum-based anticancer agent by orthogonal double-click chemistry.
Academic Article Redesigning the DNA-targeted chromophore in platinum-acridine anticancer agents: a structure-activity relationship study.
Academic Article Design of enzymatically cleavable prodrugs of a potent platinum-containing anticancer agent.
Academic Article Inhibition of DNA Synthesis by a Platinum-Acridine Hybrid Agent Leads to Potent Cell Kill in Non-Small Cell Lung Cancer.
Academic Article Unusual Reactivity of a Potent Platinum-Acridine Hybrid Antitumor Agent.
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  • Platinum