| Item Type | Name |
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Academic Article
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Phase I safety assessment of intrathecal injection of an American formulation of adenosine in humans.
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Academic Article
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Preliminary efficacy assessment of intrathecal injection of an American formulation of adenosine in humans.
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Academic Article
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Intrathecal adenosine following spinal nerve ligation in rat: short residence time in cerebrospinal fluid and no change in A(1) receptor binding.
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Academic Article
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Peripheral nerve injury alters the alpha2 adrenoceptor subtype activated by clonidine for analgesia.
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Academic Article
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Safety in numbers: how do we study toxicity of spinal analgesics?
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Academic Article
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Analgesia from a peripherally active kappa-opioid receptor agonist in patients with chronic pancreatitis.
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Academic Article
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Clonidine-induced neuronal activation in the spinal cord is altered after peripheral nerve injury.
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Academic Article
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Individual differences in pain sensitivity: implications for treatment decisions.
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Academic Article
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Intrathecal, but not intravenous adenosine reduces allodynia in patients with neuropathic pain.
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Academic Article
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Polyanalgesic Consensus Conference 2003: an update on the management of pain by intraspinal drug delivery-- report of an expert panel.
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Academic Article
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Effects of laparotomy on spontaneous exploratory activity and conditioned operant responding in the rat: a model for postoperative pain.
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Academic Article
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The antinociceptive effects of spinal cyclooxygenase inhibitors on uterine cervical distension.
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Academic Article
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Intrathecal morphine and ketorolac analgesia after surgery: comparison of spontaneous and elicited responses in rats.
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Academic Article
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Intravenous butorphanol, meperidine, and their combination relieve pain and distress in women in labor.
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Academic Article
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Clonidine maintains intrathecal self-administration in rats following spinal nerve ligation.
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Academic Article
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Clonidine reduces hypersensitivity and alters the balance of pro- and anti-inflammatory leukocytes after local injection at the site of inflammatory neuritis.
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Academic Article
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Opioid self-administration in the nerve-injured rat: relevance of antiallodynic effects to drug consumption and effects of intrathecal analgesics.
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Academic Article
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Gabapentin activates spinal noradrenergic activity in rats and humans and reduces hypersensitivity after surgery.
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Academic Article
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Brain derived nerve growth factor induces spinal noradrenergic fiber sprouting and enhances clonidine analgesia following nerve injury in rats.
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Academic Article
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Epidural neostigmine: will it replace lipid soluble opioids for postoperative and labor analgesia?
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Academic Article
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Up-regulation of spinal glutamate transporters contributes to anti-hypersensitive effects of valproate in rats after peripheral nerve injury.
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Academic Article
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Estrogen reduces efficacy of mu- but Not kappa-opioid agonist inhibition in response to uterine cervical distension.
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Academic Article
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Effect of kappa opioid agonists on visceral nociception induced by uterine cervical distension in rats.
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Academic Article
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Dose response of intrathecal adenosine in experimental pain and allodynia.
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Academic Article
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Pharmacology of opioid inhibition to noxious uterine cervical distension.
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Academic Article
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Spinal adrenergic and cholinergic receptor interactions activated by clonidine in postincisional pain.
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Academic Article
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Intrathecal morphine reduces the visceromotor response to acute uterine cervical distension in an estrogen-independent manner.
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Academic Article
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Cephalad movement of morphine and fentanyl in humans after intrathecal injection.
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Academic Article
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Plasticity in action of intrathecal clonidine to mechanical but not thermal nociception after peripheral nerve injury.
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Academic Article
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Intravenous remifentanil produces withdrawal hyperalgesia in volunteers with capsaicin-induced hyperalgesia.
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Academic Article
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Intrathecal but not intravenous opioids release adenosine from the spinal cord.
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Academic Article
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alpha2-Adrenoceptor activation by clonidine enhances stimulation-evoked acetylcholine release from spinal cord tissue after nerve ligation in rats.
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Academic Article
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Multifactorial preoperative predictors for postcesarean section pain and analgesic requirement.
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Academic Article
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Treating and preventing chronic pain: a view from the spinal cord--Bonica Lecture, ASRA Annual Meeting, 2005.
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Academic Article
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Analgesia induced by perineural clonidine is enhanced in persistent neuritis.
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Academic Article
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Oral gabapentin activates spinal cholinergic circuits to reduce hypersensitivity after peripheral nerve injury and interacts synergistically with oral donepezil.
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Academic Article
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ST91 [2-(2,6-diethylphenylamino)-2-imidazoline hydrochloride]-mediated spinal antinociception and synergy with opioids persists in the absence of functional alpha-2A- or alpha-2C-adrenergic receptors.
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Academic Article
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Assessment of behavior during labor in rats and effect of intrathecal morphine.
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Academic Article
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Animal models and the prediction of efficacy in clinical trials of analgesic drugs: a critical appraisal and call for uniform reporting standards.
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Academic Article
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Multiplicative interactions to enhance gabapentin to treat neuropathic pain.
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Academic Article
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The effect of peripherally administered CDP-choline in an acute inflammatory pain model: the role of alpha7 nicotinic acetylcholine receptor.
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Academic Article
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Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat.
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Academic Article
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A tropomyosine receptor kinase inhibitor blocks spinal neuroplasticity essential for the anti-hypersensitivity effects of gabapentin and clonidine in rats with peripheral nerve injury.
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Academic Article
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Oxytocin inhibits the membrane depolarization-induced increase in intracellular calcium in capsaicin sensitive sensory neurons: a peripheral mechanism of analgesic action.
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Academic Article
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Depletion of endogenous noradrenaline does not prevent spinal cord plasticity following peripheral nerve injury.
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Academic Article
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Opioid-independent mechanisms supporting offset analgesia and temporal sharpening of nociceptive information.
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Concept
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Analgesics, Opioid
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Concept
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Analgesics, Non-Narcotic
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Concept
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Analgesics
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Academic Article
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Peripheral nerve injury and gabapentin, but not their combination, impair attentional behavior via direct effects on noradrenergic signaling in the brain.
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Academic Article
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Phase 1 safety assessment of intrathecal oxytocin.
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Academic Article
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Failure of intrathecal ketorolac to reduce remifentanil-induced postinfusion hyperalgesia in humans.
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Academic Article
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Intrathecal clonidine and adenosine: effects on pain and sensory processing in patients with chronic regional pain syndrome.
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Academic Article
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Wherefore Gabapentinoids?: Was There Rush Too Soon to Judgment?
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Academic Article
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Mindfulness-Meditation-Based Pain Relief Is Not Mediated by Endogenous Opioids.
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Academic Article
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Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations.
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Academic Article
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Gabapentin loses efficacy over time after nerve injury in rats: role of glutamate transporter-1 in the locus coeruleus.
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Grant
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Receptor Selective Spinal Analgesia
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Academic Article
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Epidural Neostigmine versus Fentanyl to Decrease Bupivacaine Use in Patient-controlled Epidural Analgesia during Labor: A Randomized, Double-blind, Controlled Study.
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Academic Article
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Assessment of Behavioral Disruption in Rats with Abdominal Inflammation Using Visual Cue Titration and the Five-choice Serial-reaction Time Task.
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Academic Article
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Incisional Nociceptive Input Impairs Attention-related Behavior and Is Associated with Reduced Neuronal Activity in the Prefrontal Cortex in Rats.
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Academic Article
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Liposomal Bupivacaine Infiltration for Knee Arthroplasty: Significant Analgesic Benefits or Just a Bunch of Fat?
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Academic Article
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Pain after surgery.
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Academic Article
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Improving Preclinical Development of Novel Interventions to Treat Pain: Insanity Is Doing the Same Thing Over and Over and Expecting Different Results.
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