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Langefeld, Carl
One or more keywords matched the following items that are connected to Langefeld, Carl
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Academic Article Genetic linkage and association of Fcgamma receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus.
Academic Article Association of an IL-1A 3'UTR polymorphism with end-stage renal disease and IL-1 alpha expression.
Academic Article Exploring pleiotropy using principal components.
Academic Article Power for genetic association studies with random allele frequencies and genotype distributions.
Academic Article Association analysis of the plasminogen activator inhibitor-1 4G/5G polymorphism in Hispanics and African Americans: the IRAS family study.
Academic Article Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes.
Academic Article Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study.
Academic Article T-786C polymorphism of the endothelial nitric oxide synthase gene is associated with albuminuria in the diabetes heart study.
Academic Article P-selectin gene haplotype associations with albuminuria in the Diabetes Heart Study.
Academic Article Two-locus genome-wide linkage scan for prostate cancer susceptibility genes with an interaction effect.
Academic Article A functional polymorphism in the lymphotoxin-alpha gene is associated with carotid artery wall thickness: the Diabetes Heart Study.
Academic Article Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data.
Academic Article A leucine repeat in the carnosinase gene CNDP1 is associated with diabetic end-stage renal disease in European Americans.
Academic Article The association between innate immunity gene (IRAK1) and C-reactive protein in the Diabetes Heart Study.
Academic Article Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy.
Academic Article Association of the proprotein convertase subtilisin/kexin-type 2 (PCSK2) gene with type 2 diabetes in an African American population.
Academic Article Comprehensive evaluation of the estrogen receptor alpha gene reveals further evidence for association with type 2 diabetes enriched for nephropathy in an African American population.
Academic Article Association analysis of the ephrin-B2 gene in African-Americans with end-stage renal disease.
Academic Article Polymorphisms near SOCS3 are associated with obesity and glucose homeostasis traits in Hispanic Americans from the Insulin Resistance Atherosclerosis Family Study.
Academic Article Relationship between genetic variants in myocardial sodium and potassium channel genes and QT interval duration in diabetics: the Diabetes Heart Study.
Academic Article Polymorphisms in the nonmuscle myosin heavy chain 9 gene (MYH9) are associated with albuminuria in hypertensive African Americans: the HyperGEN study.
Academic Article Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study.
Academic Article Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus.
Academic Article The influence of carnosinase gene polymorphisms on diabetic nephropathy risk in African-Americans.
Academic Article Bone morphogenetic protein 7 (BMP7) gene polymorphisms are associated with inverse relationships between vascular calcification and BMD: the Diabetes Heart Study.
Academic Article Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD.
Academic Article Variant in the 3' region of the IkappaBalpha gene associated with insulin resistance in Hispanic Americans: The IRAS Family Study.
Academic Article Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study.
Academic Article Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans.
Academic Article Molecular basis of a linkage peak: exome sequencing and family-based analysis identify a rare genetic variant in the ADIPOQ gene in the IRAS Family Study.
Academic Article Single-nucleotide polymorphisms in the TNF gene are associated with obesity-related phenotypes in vervet monkeys.
Academic Article Common variants in the periostin gene influence development of atherosclerosis in young persons.
Academic Article The impact of FADS genetic variants on ?6 polyunsaturated fatty acid metabolism in African Americans.
Academic Article Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.
Academic Article Identification of ATPAF1 as a novel candidate gene for asthma in children.
Academic Article Sickle cell trait is not independently associated with susceptibility to end-stage renal disease in African Americans.
Academic Article Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus.
Academic Article Genetic association and gene-gene interaction analyses in African American dialysis patients with nondiabetic nephropathy.
Academic Article Genetic variation in the peroxisome proliferator activated receptor-gamma gene is associated with histologically advanced NAFLD.
Academic Article Evaluation of TRAF6 in a large multiancestral lupus cohort.
Academic Article Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap.
Academic Article Immune function genes CD99L2, JARID2 and TPO show association with autism spectrum disorder.
Academic Article Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans.
Academic Article Brief report: enrichment of associations in genes with fibrosis, apoptosis, and innate immunity functions with cardiac manifestations of neonatal lupus.
Academic Article Relevance of the ACTN4 gene in African-Americans with non-diabetic end-stage renal disease.
Academic Article Estimating the contributions of rare and common genetic variations and clinical measures to a model trait: adiponectin.
Academic Article Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study.
Academic Article MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus.
Academic Article Nucleotide variation, haplotype structure, and association with end-stage renal disease of the human interleukin-1 gene cluster.
Academic Article A genome-wide search for allergic response (atopy) genes in three ethnic groups: Collaborative Study on the Genetics of Asthma.
Academic Article Interaction effect of PTEN and CDKN1B chromosomal regions on prostate cancer linkage.
Academic Article Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.
Academic Article Association of the mu-opioid receptor gene with type 2 diabetes mellitus in an African American population.
Academic Article Association of proopiomelanocortin gene polymorphisms with obesity in the IRAS family study.
Academic Article Variants of the CD40 gene but not of the CD40L gene are associated with coronary artery calcification in the Diabetes Heart Study (DHS).
Academic Article Genome-wide linkage of plasma adiponectin reveals a major locus on chromosome 3q distinct from the adiponectin structural gene: the IRAS family study.
Academic Article Investigation of the estrogen receptor-alpha gene with type 2 diabetes and/or nephropathy in African-American and European-American populations.
Academic Article Association of the estrogen receptor-alpha gene with the metabolic syndrome and its component traits in African-American families: the Insulin Resistance Atherosclerosis Family Study.
Academic Article Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans.
Academic Article Association of the distal region of the ectonucleotide pyrophosphatase/phosphodiesterase 1 gene with type 2 diabetes in an African-American population enriched for nephropathy.
Academic Article Genetic analysis of the soluble epoxide hydrolase gene, EPHX2, in subclinical cardiovascular disease in the Diabetes Heart Study.
Academic Article Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease.
Academic Article Genetic admixture: a tool to identify diabetic nephropathy genes in African Americans.
Academic Article Association of the Kir6.2 E23K variant with reduced acute insulin response in African-Americans.
Academic Article Association of adiponectin gene polymorphisms with type 2 diabetes in an African American population enriched for nephropathy.
Academic Article Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African Americans.
Academic Article Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease.
Academic Article Juvenile idiopathic arthritis and HLA class I and class II interactions and age-at-onset effects.
Academic Article Association of polymorphisms in the klotho gene with severity of non-diabetic ESRD in African Americans.
Academic Article The acetyl-coenzyme A carboxylase beta (ACACB) gene is associated with nephropathy in Chinese patients with type 2 diabetes.
Academic Article The non-muscle Myosin heavy chain 9 gene (MYH9) is not associated with lupus nephritis in African Americans.
Academic Article Candidate genes for non-diabetic ESRD in African Americans: a genome-wide association study using pooled DNA.
Academic Article Association of trypanolytic ApoL1 variants with kidney disease in African Americans.
Academic Article The apolipoprotein L1 (APOL1) gene and nondiabetic nephropathy in African Americans.
Academic Article The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1.
Academic Article Resequencing and analysis of variation in the TCF7L2 gene in African Americans suggests that SNP rs7903146 is the causal diabetes susceptibility variant.
Academic Article A genome-wide association study for diabetic nephropathy genes in African Americans.
Academic Article Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus.
Academic Article Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans.
Academic Article Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome.
Academic Article Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study.
Academic Article Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus.
Academic Article A genome-wide association search for type 2 diabetes genes in African Americans.
Academic Article Association of APOL1 variants with mild kidney disease in the first-degree relatives of African American patients with non-diabetic end-stage renal disease.
Academic Article Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans.
Academic Article Polymorphisms in the Selenoprotein S gene and subclinical cardiovascular disease in the Diabetes Heart Study.
Concept Major Histocompatibility Complex
Concept Genome Components
Concept Gene Expression Regulation, Enzymologic
Concept Genome, Human
Concept Open Reading Frames
Concept Amino Acid Sequence
Concept Genetic Loci
Concept Genome
Concept Gene Expression Regulation
Concept Gene Expression Profiling
Concept Gene Regulatory Networks
Concept Multigene Family
Concept Genes, Tumor Suppressor
Concept Epistasis, Genetic
Concept Gene Expression
Concept Polymorphism, Single Nucleotide
Concept Genes, Dominant
Concept Quantitative Trait Loci
Concept Gene Frequency
Concept Gene Deletion
Concept Base Sequence
Concept Alleles
Concept Genes, Recessive
Concept Gene Knockdown Techniques
Concept Molecular Sequence Data
Academic Article A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
Academic Article Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
Academic Article Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.
Academic Article Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry.
Academic Article PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes.
Academic Article Characterization of European ancestry nonalcoholic fatty liver disease-associated variants in individuals of African and Hispanic descent.
Academic Article Variants in adiponectin signaling pathway genes show little association with subclinical CVD in the diabetes heart study.
Academic Article Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
Academic Article JC polyoma virus interacts with APOL1 in African Americans with nondiabetic nephropathy.
Academic Article Genetic variants in selenoprotein P plasma 1 gene (SEPP1) are associated with fasting insulin and first phase insulin response in Hispanics.
Academic Article Testing gene-environment interactions in family-based association studies using trait-based ascertained samples.
Academic Article Gene-gene interactions in APOL1-associated nephropathy.
Academic Article Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease.
Academic Article Complement factor H gene associations with end-stage kidney disease in African Americans.
Academic Article Genes associated with SLE are targets of recent positive selection.
Academic Article Coding variants in nephrin (NPHS1) and susceptibility to nephropathy in African Americans.
Academic Article The ras responsive transcription factor RREB1 is a novel candidate gene for type 2 diabetes associated end-stage kidney disease.
Academic Article Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial.
Academic Article A comparison of type 2 diabetes risk allele load between African Americans and European Americans.
Academic Article Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium.
Academic Article IL-6 trans-signaling increases expression of airways disease genes in airway smooth muscle.
Academic Article An Islet-Targeted Genome-Wide Association Scan Identifies Novel Genes Implicated in Cytokine-Mediated Islet Stress in Type 2 Diabetes.
Academic Article Deceased donor multidrug resistance protein 1 and caveolin 1 gene variants may influence allograft survival in kidney transplantation.
Academic Article Re-Sequencing of the APOL1-APOL4 and MYH9 Gene Regions in African Americans Does Not Identify Additional Risks for CKD Progression.
Academic Article HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis.
Academic Article Tissue-Specific and Genetic Regulation of Insulin Sensitivity-Associated Transcripts in African Americans.
Academic Article Genetic analysis of advanced glycation end products in the DHS MIND study.
Academic Article Genome-wide imputation study identifies novel HLA locus for pulmonary fibrosis and potential role for auto-immunity in fibrotic idiopathic interstitial pneumonia.
Academic Article Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin.
Academic Article Mapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity.
Academic Article APOL1 Renal-Risk Variants Induce Mitochondrial Dysfunction.
Academic Article Analysis of Whole Exome Sequencing with Cardiometabolic Traits Using Family-Based Linkage and Association in the IRAS Family Study.
Academic Article Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.
Academic Article Rare and low-frequency coding variants alter human adult height.
Grant Genetic Architecture of Obesity and Inflammation in Hispanic Americans
Grant Genetics of Juvenile Idiopathic Arthritis and Subtypes
Grant Exome Sequencing to Identify CVD Risk Variants in Hispanics & African Americans
Academic Article A genome-wide linkage and association analysis of imputed insertions and deletions with cardiometabolic phenotypes in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study.
Academic Article A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy.
Academic Article The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue.
Academic Article Genetic regulation of adipose tissue transcript expression is involved in modulating serum triglyceride and HDL-cholesterol.
Grant Genetics and the Microbiome in Anti-Ro Preclinical and Established Autoimmunity
Academic Article Genetic architecture of lipid traits in the Hispanic community health study/study of Latinos.
Academic Article Early-life environmental exposures interact with genetic susceptibility variants in pediatric patients with eosinophilic esophagitis.
Academic Article Adipose Tissue Transferrin and Insulin Resistance.
Academic Article The African Descent and Glaucoma Evaluation Study (ADAGES) III: Contribution of Genotype to Glaucoma Phenotype in African Americans: Study Design and Baseline Data.
Academic Article Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions.
Academic Article Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations.
Academic Article Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
Academic Article Trans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks.
Academic Article Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Academic Article Genetic Architecture of Primary Open-Angle Glaucoma in Individuals of African Descent: The African Descent and Glaucoma Evaluation Study III.
Academic Article Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
Academic Article Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
Academic Article A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.
Academic Article A molecular biomarker for prediction of clinical outcome in children with ASD, constipation, and intestinal inflammation.
Academic Article Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients.
Academic Article Integrative analysis of DNA methylation in discordant twins unveils distinct architectures of systemic sclerosis subsets.
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