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Orr, Miranda
One or more keywords matched the following items that are connected to Orr, Miranda
Item TypeName
Concept tau Proteins
Concept Tauopathies
Academic Article Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology.
Academic Article A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies.
Academic Article Genotype-specific differences between mouse CNS stem cell lines expressing frontotemporal dementia mutant or wild type human tau.
Academic Article Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent.
Academic Article Tau protein aggregation is associated with cellular senescence in the brain.
Grant Novel Stem Cell and Mouse Models to Study Frontotemporal Dementia
Grant Alzheimer's Disease Associated Tau Toxicity Induces Cellular Senescence in Brain
Grant High Resolution Profiling of Senescent Neurons and Their Microenvironments in Postmortem Human Brain Tissue Spanning Eight Decades of Life
Academic Article Preliminary mechanistic insights of a brain-penetrant microtubule imaging PET ligand in a tau-knockout mouse model.
Grant Development of an Innovative Vervet (Chlorocebus aethiops sabaeus) Model of Early Alzheimer's-like Neuropathology and Symptomatology
Grant Investigating the Role of Tau Protein in Neuronal Senescence Induction and Maintenance
Grant Evaluating microtubule binding as a potential imaging biomarker for Alzheimer's disease
Grant Alzheimer’s disease-associated tau toxicity induces cellular senescence in the brain.
Academic Article Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology.
Academic Article Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD): A Pilot Clinical Trial.
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  • Tau