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Hollis, Thomas
One or more keywords matched the following items that are connected to
Hollis, Thomas
Item Type
Name
Academic Article
Essential amino acid residues in the single-stranded DNA-binding protein of bacteriophage T7. Identification of the dimer interface.
Academic Article
The TREX1 exonuclease R114H mutation in Aicardi-Goutières syndrome and lupus reveals dimeric structure requirements for DNA degradation activity.
Academic Article
Sequence variants in the 3'-->5' deoxyribonuclease TREX2: identification in a genetic screen and effects on catalysis by the recombinant proteins.
Academic Article
RNaseH2 mutants that cause Aicardi-Goutieres syndrome are active nucleases.
Academic Article
Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome.
Concept
Amino Acid Substitution
Academic Article
The Arg-62 residues of the TREX1 exonuclease act across the dimer interface contributing to catalysis in the opposing protomers.
Search Criteria
Amino Acid Substitution