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RNaseH2 mutants that cause Aicardi-Goutieres syndrome are active nucleases.
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RNaseH2 mutants that cause Aicardi-Goutieres syndrome are active nucleases.
Perrino FW, Harvey S, Shaban NM, Hollis T. RNaseH2 mutants that cause Aicardi-Goutieres syndrome are active nucleases. J Mol Med (Berl). 2009 Jan; 87(1):25-30.
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PubMed
subject areas
Amino Acid Substitution
Brain Diseases, Metabolic, Inborn
Catalytic Domain
Humans
Mutation, Missense
Protein Structure, Quaternary
Ribonuclease H
Syndrome
authors with profiles
Thomas Hollis PhD