A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))

Descriptor ID	D007562
MeSH Number(s)	C10.228.140.380.165 C10.228.228.800.230 F03.087.400.300
Concept/Terms	Creutzfeldt-Jakob Syndrome Creutzfeldt-Jakob Syndrome Creutzfeldt Jakob Syndrome Syndrome, Creutzfeldt-Jakob Creutzfeldt Jacob Disease Disease, Creutzfeldt Jacob Jacob Disease, Creutzfeldt Creutzfeldt-Jakob Disease Creutzfeldt Jakob Disease Disease, Creutzfeldt-Jakob Jakob-Creutzfeldt Syndrome Jakob Creutzfeldt Syndrome Syndrome, Jakob-Creutzfeldt Spongiform Encephalopathy, Subacute Encephalopathies, Subacute Spongiform Encephalopathy, Subacute Spongiform Spongiform Encephalopathies, Subacute Subacute Spongiform Encephalopathies Subacute Spongiform Encephalopathy CJD (Creutzfeldt-Jakob Disease) CJD (Creutzfeldt Jakob Disease) Jakob-Creutzfeldt Disease Disease, Jakob-Creutzfeldt Jakob Creutzfeldt Disease Creutzfeldt-Jakob Disease, Familial Creutzfeldt-Jakob Disease, Familial Creutzfeldt Jakob Disease, Familial Creutzfeldt-Jakob Diseases, Familial Disease, Familial Creutzfeldt-Jakob Familial Creutzfeldt-Jakob Diseases Familial Creutzfeldt-Jakob Disease Familial Creutzfeldt Jakob Disease New Variant Creutzfeldt-Jakob Disease New Variant Creutzfeldt-Jakob Disease New Variant Creutzfeldt Jakob Disease Variant Creutzfeldt-Jakob Disease Variant Creutzfeldt Jakob Disease V-CJD (Variant-Creutzfeldt-Jakob Disease) V CJD (Variant Creutzfeldt Jakob Disease) Creutzfeldt-Jakob Disease, New Variant Creutzfeldt Jakob Disease, New Variant Creutzfeldt-Jakob Disease, Variant Creutzfeldt Jakob Disease, Variant

Below are MeSH descriptors whose meaning is more general than "Creutzfeldt-Jakob Syndrome".

Below are MeSH descriptors whose meaning is related to "Creutzfeldt-Jakob Syndrome".

Below are MeSH descriptors whose meaning is more specific than "Creutzfeldt-Jakob Syndrome".