An autosomal dominant disorder caused by deletion of the proximal long arm of the paternal chromosome 15 (15q11-q13) or by inheritance of both of the pair of chromosomes 15 from the mother (UNIPARENTAL DISOMY) which are imprinted (GENETIC IMPRINTING) and hence silenced. Clinical manifestations include MENTAL RETARDATION; MUSCULAR HYPOTONIA; HYPERPHAGIA; OBESITY; short stature; HYPOGONADISM; STRABISMUS; and HYPERSOMNOLENCE. (Menkes, Textbook of Child Neurology, 5th ed, p229)

Descriptor ID	D011218
MeSH Number(s)	C10.597.606.643.690 C16.131.077.730 C16.131.260.700 C16.320.180.700 C18.654.726.500.740
Concept/Terms	Prader-Willi Syndrome Prader-Willi Syndrome Prader Willi Syndrome Syndrome, Prader-Willi Willi-Prader Syndrome Syndrome, Willi-Prader Willi Prader Syndrome Prader Labhart Willi Syndrome Prader-Labhart-Willi Syndrome Syndrome, Prader-Labhart-Willi Labhart-Willi Syndrome Labhart Willi Syndrome Syndrome, Labhart-Willi Labhart-Willi-Prader-Fanconi Syndrome Labhart Willi Prader Fanconi Syndrome Syndrome, Labhart-Willi-Prader-Fanconi Royer Syndrome Royer Syndrome Syndrome, Royer Royer's Syndrome Royers Syndrome Syndrome, Royer's

Below are MeSH descriptors whose meaning is more general than "Prader-Willi Syndrome".

Below are MeSH descriptors whose meaning is related to "Prader-Willi Syndrome".

Below are MeSH descriptors whose meaning is more specific than "Prader-Willi Syndrome".