"Microbial Collagenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.
Descriptor ID |
D003012
|
MeSH Number(s) |
D08.811.277.656.300.480.205.500 D08.811.277.656.675.374.205.500
|
Concept/Terms |
Microbial Collagenase- Microbial Collagenase
- Collalysine
- Clostridium histolyticum Collagenase
- Collagenase, Clostridium histolyticum
- Collagenase, Microbial
- Clostridiopeptidase A
- Nucleolysin
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Below are MeSH descriptors whose meaning is more general than "Microbial Collagenase".
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