Cimetidine

"Cimetidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRINS output. It also blocks the activity of CYTOCHROME P-450 which might explain proposals for use in NEOADJUVANT THERAPY.

Descriptor ID	D002927
MeSH Number(s)	D02.078.370.200 D03.383.129.308.130
Concept/Terms	Cimetidine Cimetidine N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine Biomet Biomet Biomet400 Biomet400 Cimetidine Hydrochloride Cimetidine Hydrochloride Hydrochloride, Cimetidine Cimetidine HCl HCl, Cimetidine Tagamet Tagamet Histodil Histodil SK&F-92334 SK&F-92334 SK&F 92334 SK&F92334 SKF-92334 SKF 92334 SKF92334 Altramet Altramet Eureceptor Eureceptor

Below are MeSH descriptors whose meaning is more general than "Cimetidine".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Amidines [D02.078]
Guanidines [D02.078.370]
Cimetidine [D02.078.370.200]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Azoles [D03.383.129]
Imidazoles [D03.383.129.308]
Cimetidine [D03.383.129.308.130]

Below are MeSH descriptors whose meaning is more specific than "Cimetidine".

publications

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