Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS, AVIAN), v-erbA. In cells, erbA genes encode thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsiveness but not DNA binding capacity.

Descriptor ID	D018776
MeSH Number(s)	G05.360.340.024.340.375.500.791.290
Concept/Terms	Genes, erbA Genes, erbA erbA Gene erbA Genes Genes, erbA-beta Genes, erbA-beta erbA-beta Gene erbA-beta Genes Genes, erbA beta beta Gene, erbA beta Genes, erbA erbA beta Gene erbA beta Genes Genes, TR-beta TR-beta Gene TR-beta Genes Genes, TR beta TR beta Gene TR beta Genes beta Gene, TR beta Genes, TR Genes, THRB Gene, THRB THRB Gene THRB Genes Genes, erbA-alpha Genes, erbA-alpha erbA-alpha Gene erbA-alpha Genes Genes, erbA alpha alpha Gene, erbA alpha Genes, erbA erbA alpha Gene erbA alpha Genes Genes, TR-alpha TR-alpha Gene TR-alpha Genes Genes, TR alpha TR alpha Gene TR alpha Genes alpha Gene, TR alpha Genes, TR Genes, THRA Gene, THRA THRA Gene THRA Genes v-erbA Genes v-erbA Genes v erbA Genes v-erbA Gene v-erbA Oncogenes v erbA Oncogenes v-erbA Oncogene c-erbA Genes c-erbA Genes c erbA Genes c-erbA Gene c-erbA Proto-Oncogenes c erbA Proto Oncogenes c-erbA Proto-Oncogene

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