Tissue Inhibitor of Metalloproteinase-2
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"Tissue Inhibitor of Metalloproteinase-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21-kDa nonglycosylated protein found in tissue fluid and is secreted as a complex with progelatinase A by human fibroblast and uncomplexed from alveolar macrophages. An overexpression of TIMP-2 has been shown to inhibit invasive and metastatic activity of tumor cells and decrease tumor growth in vivo.
    
			
			
				
				
					
						| Descriptor ID | D019716 | 
					
						| MeSH Number(s) | D12.776.645.875.500 | 
					
						| Concept/Terms |  | 
					
				
			 
			
				Below are MeSH descriptors whose meaning is more general than "Tissue Inhibitor of Metalloproteinase-2".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Tissue Inhibitor of Metalloproteinase-2".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 2019 | 1 | 0 | 1 | 
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				Below are the most recent publications written about "Tissue Inhibitor of Metalloproteinase-2" by people in Profiles.