Tumor Necrosis Factor-alpha
"Tumor Necrosis Factor-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.
| Descriptor ID |
D014409
|
| MeSH Number(s) |
D12.644.276.374.500.800 D12.644.276.374.750.626 D12.644.276.972.626 D12.776.124.900 D12.776.395.930 D12.776.467.374.500.800 D12.776.467.374.750.626 D12.776.467.972.626 D23.529.374.500.800 D23.529.374.750.626 D23.529.972.626
|
| Concept/Terms |
Tumor Necrosis Factor-alpha- Tumor Necrosis Factor-alpha
- Tumor Necrosis Factor alpha
- Cachectin-Tumor Necrosis Factor
- Cachectin Tumor Necrosis Factor
- TNFalpha
- TNF-alpha
- Tumor Necrosis Factor
- Tumor Necrosis Factor Ligand Superfamily Member 2
- Cachectin
- TNF Superfamily, Member 2
|
Below are MeSH descriptors whose meaning is more general than "Tumor Necrosis Factor-alpha".
Below are MeSH descriptors whose meaning is more specific than "Tumor Necrosis Factor-alpha".
This graph shows the total number of publications written about "Tumor Necrosis Factor-alpha" by people in this website by year, and whether "Tumor Necrosis Factor-alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 |
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 2 | 3 |
| 2000 | 0 | 1 | 1 |
| 2001 | 3 | 1 | 4 |
| 2002 | 3 | 3 | 6 |
| 2003 | 4 | 3 | 7 |
| 2004 | 3 | 7 | 10 |
| 2005 | 2 | 7 | 9 |
| 2006 | 2 | 4 | 6 |
| 2007 | 1 | 6 | 7 |
| 2008 | 1 | 9 | 10 |
| 2009 | 3 | 10 | 13 |
| 2010 | 4 | 11 | 15 |
| 2011 | 5 | 4 | 9 |
| 2012 | 3 | 4 | 7 |
| 2013 | 3 | 4 | 7 |
| 2014 | 3 | 4 | 7 |
| 2015 | 6 | 2 | 8 |
| 2016 | 3 | 5 | 8 |
| 2017 | 0 | 5 | 5 |
| 2018 | 3 | 4 | 7 |
| 2019 | 1 | 5 | 6 |
| 2020 | 1 | 1 | 2 |
| 2021 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tumor Necrosis Factor-alpha" by people in Profiles.