A mixed-function oxygenase that catalyzes the hydroxylation of a prolyl-glycyl-containing-peptide, usually in PROTOCOLLAGEN, to a hydroxyprolylglycyl-containing-peptide. The enzyme utilizes molecular OXYGEN with a concomitant oxidative decarboxylation of 2-oxoglutarate to SUCCINATE. The enzyme occurs as a tetramer of two alpha and two beta subunits. The beta subunit of procollagen-proline dioxygenase is identical to the enzyme PROTEIN DISULFIDE-ISOMERASES.

Descriptor ID	D011393
MeSH Number(s)	D08.811.682.690.708.673
Concept/Terms	Procollagen-Proline Dioxygenase Procollagen-Proline Dioxygenase Dioxygenase, Procollagen-Proline Procollagen Proline Dioxygenase Procollagen Prolyl 4-Hydroxylase 4-Hydroxylase, Procollagen Prolyl Procollagen Prolyl 4 Hydroxylase Prolyl 4-Hydroxylase, Procollagen Protocollagen Prolyl Hydroxylase Hydroxylase, Protocollagen Prolyl Prolyl Hydroxylase, Protocollagen Proline,2-Oxoglutarate 4-Dioxygenase 4-Dioxygenase, Proline,2-Oxoglutarate Proline,2 Oxoglutarate 4 Dioxygenase Prolyl 4-Hydroxylase 4-Hydroxylase, Prolyl Prolyl 4 Hydroxylase Prolyl Hydroxylase Hydroxylase, Prolyl Peptidyl Prolyl Hydroxylase Hydroxylase, Peptidyl Prolyl Prolyl Hydroxylase, Peptidyl Proline Hydroxylase Hydroxylase, Proline

Below are MeSH descriptors whose meaning is more general than "Procollagen-Proline Dioxygenase".

Below are MeSH descriptors whose meaning is related to "Procollagen-Proline Dioxygenase".

Below are MeSH descriptors whose meaning is more specific than "Procollagen-Proline Dioxygenase".