Metabolic Detoxication, Phase II
"Metabolic Detoxication, Phase II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include GLUTATHIONE conjugation; ACYLATION; and AMINATION. Phase II enzymes include GLUTATHIONE TRANSFERASE and GLUCURONOSYLTRANSFERASE. In a sense these reactions detoxify phase I reaction products.
| Descriptor ID |
D050217
|
| MeSH Number(s) |
G03.495.244.820.750 G07.690.812.097.600.750 G07.700.680.097.600.750
|
| Concept/Terms |
Metabolic Detoxication, Phase II- Metabolic Detoxication, Phase II
- Phase II Detoxification
- Detoxification, Phase II
- Detoxifications, Phase II
- Phase II Detoxifications
- Metabolic Detoxication, Conjugative
- Conjugative Metabolic Detoxication
- Conjugative Metabolic Detoxications
- Detoxication, Conjugative Metabolic
- Detoxications, Conjugative Metabolic
- Metabolic Detoxications, Conjugative
- Metabolic Detoxification, Phase II
|
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