"Presenilins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Integral membrane proteins and essential components of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PEPTIDES precursors. Mutations of presenilins lead to presenile ALZHEIMER DISEASE with onset before age 65 years.
| Descriptor ID |
D053763
|
| MeSH Number(s) |
D12.776.543.696
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Presenilins".
Below are MeSH descriptors whose meaning is more specific than "Presenilins".
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Below are the most recent publications written about "Presenilins" by people in Profiles.