Protein Tyrosine Phosphatase, Non-Receptor Type 12
"Protein Tyrosine Phosphatase, Non-Receptor Type 12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of a N-terminal catalytic domain and a large C-terminal domain that is enriched in PROLINE, GLUTAMIC ACID, SERINE, and THREONINE residues (PEST sequences). The phosphatase subtype is ubiquitously expressed and implicated in the regulation of a variety of biological processes such as CELL MOVEMENT; CYTOKINESIS; focal adhesion disassembly; and LYMPHOCYTE ACTIVATION.
| Descriptor ID |
D054594
|
| MeSH Number(s) |
D08.811.277.352.650.775.300.850 D12.644.360.585.850 D12.776.476.564.850
|
| Concept/Terms |
Protein Tyrosine Phosphatase, Non-Receptor Type 12- Protein Tyrosine Phosphatase, Non-Receptor Type 12
- Protein Tyrosine Phosphatase, Non Receptor Type 12
- PTP-PEST
- PEST-Enriched Phosphatase
- PEST Enriched Phosphatase
- Phosphatase, PEST-Enriched
- PEP Protein Tyrosine Phosphatase
- PEP PTPase
- PTPase, PEP
|
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