A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or a general medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)

Descriptor ID	D005879
MeSH Number(s)	C10.228.140.079.898 C10.228.662.825.800 C10.574.500.850 C16.320.400.820 F03.550.825.850
Concept/Terms	Tourette Syndrome Tourette Syndrome Combined Vocal and Multiple Motor Tic Disorder Gilles de la Tourette Syndrome Gilles de la Tourette's Disease Tourette's Syndrome Syndrome, Tourette's Tourettes Syndrome Tic Disorder, Combined Vocal and Multiple Motor Tourette Disease Tourette Disorder Tourette's Disease Tourettes Disease Tourette's Disorder Tourettes Disorder Combined Multiple Motor and Vocal Tic Disorder Multiple Motor and Vocal Tic Disorder, Combined

Below are MeSH descriptors whose meaning is more general than "Tourette Syndrome".

Below are MeSH descriptors whose meaning is related to "Tourette Syndrome".

Below are MeSH descriptors whose meaning is more specific than "Tourette Syndrome".