Core Binding Factor alpha Subunits

"Core Binding Factor alpha Subunits" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression.

Descriptor ID	D050657
MeSH Number(s)	D12.776.930.155.200
Concept/Terms	Core Binding Factor alpha Subunits Core Binding Factor alpha Subunits Core Binding Factor alpha Proteins Runx Proteins Polyomavirus Enhancer A Binding Protein 2 Polyomavirus Enhancer Binding Protein 2, Alpha Subunit Runt Domain Factor Acute Myeloid Leukemia Proteins PEBP2A Transcription Factors Transcription Factors, PEBP2A

Below are MeSH descriptors whose meaning is more general than "Core Binding Factor alpha Subunits".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Transcription Factors [D12.776.930]
Core Binding Factors [D12.776.930.155]
Core Binding Factor alpha Subunits [D12.776.930.155.200]

Below are MeSH descriptors whose meaning is related to "Core Binding Factor alpha Subunits".

Below are MeSH descriptors whose meaning is more specific than "Core Binding Factor alpha Subunits".

publications

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