An acylated inactive complex of streptokinase and human lysine-plasminogen. After injection, the acyl group is slowly hydrolyzed, producing an activator that converts plasminogen to plasmin, thereby initiating fibrinolysis. Its half-life is about 90 minutes compared to 5 minutes for TPA; (TISSUE PLASMINOGEN ACTIVATOR); 16 minutes for UROKINASE-TYPE PLASMINOGEN ACTIVATOR and 23 minutes for STREPTOKINASE. If treatment is initiated within 3 hours of onset of symptoms for acute myocardial infarction, the drug preserves myocardial tissue and left ventricular function and increases coronary artery patency. Bleeding complications are similar to other thrombolytic agents.

Descriptor ID	D016255
MeSH Number(s)	D08.811.277.656.300.760.635.075 D08.811.277.656.300.775.075 D08.811.277.656.959.350.635.075 D12.776.124.125.662.537.075
Concept/Terms	Anistreplase Anistreplase APSAC Anisoylated Plasminogen-Streptokinase Activator Complex Iminase Iminase Madaus Brand of Anistreplase Anistreplase Madaus Brand BRL-26921 BRL-26921 BRL 26921 BRL26921 Eminase Eminase SmithKline Beecham Brand of Anistreplase Roberts Brand of Anistreplase Anistreplase Roberts Brand Monmouth Brand Anistreplase Anistreplase, Monmouth Brand Brand Anistreplase, Monmouth Reusch Brand of Anistreplase Anistreplase Reusch Brand

Below are MeSH descriptors whose meaning is more general than "Anistreplase".

Below are MeSH descriptors whose meaning is related to "Anistreplase".

Below are MeSH descriptors whose meaning is more specific than "Anistreplase".