Mineralocorticoid Excess Syndrome, Apparent
"Mineralocorticoid Excess Syndrome, Apparent" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hereditary disease characterized by childhood onset HYPERTENSION, hypokalemic alkalosis, and low RENIN and ALDOSTERONE secretion. It results from a defect in the activity of the 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 enzyme which results in inadequate conversion of CORTISOL to CORTISONE. The build up of unprocessed cortisol to levels that stimulate MINERALOCORTICOID RECEPTORS creates the appearance of having excessive MINERALOCORTICOIDS.
Descriptor ID |
D043204
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MeSH Number(s) |
C16.320.565.925.500 C18.452.648.925.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mineralocorticoid Excess Syndrome, Apparent".
Below are MeSH descriptors whose meaning is more specific than "Mineralocorticoid Excess Syndrome, Apparent".
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