First Header Logo Second Header Logo

Nuclear Reprogramming

"Nuclear Reprogramming" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
The process that reverts CELL NUCLEI of fully differentiated somatic cells to a pluripotent or totipotent state. This process can be achieved to a certain extent by NUCLEAR TRANSFER TECHNIQUES, such as fusing somatic cell nuclei with enucleated pluripotent embryonic stem cells or enucleated totipotent oocytes. GENE EXPRESSION PROFILING of the fused hybrid cells is used to determine the degree of reprogramming. Dramatic results of nuclear reprogramming include the generation of cloned mammals, such as Dolly the sheep in 1997.


expand / collapse publications
This graph shows the total number of publications written about "Nuclear Reprogramming" by people in this website by year, and whether "Nuclear Reprogramming" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
_