"Nuclear Reprogramming" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process that reverts CELL NUCLEI of fully differentiated somatic cells to a pluripotent or totipotent state. This process can be achieved to a certain extent by NUCLEAR TRANSFER TECHNIQUES, such as fusing somatic cell nuclei with enucleated pluripotent embryonic stem cells or enucleated totipotent oocytes. GENE EXPRESSION PROFILING of the fused hybrid cells is used to determine the degree of reprogramming. Dramatic results of nuclear reprogramming include the generation of cloned mammals, such as Dolly the sheep in 1997.
| Descriptor ID |
D053708
|
| MeSH Number(s) |
G05.355.680
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nuclear Reprogramming".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Reprogramming".
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Below are the most recent publications written about "Nuclear Reprogramming" by people in Profiles.